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About the Cover
Cover: Mammalian formin Dia1 activated by RhoA localizes to cell-cell adherens junctions and strengthens them. Adherens junctions in the monolayer of MCF7 cells are visualized by immunofluorescence staining of 
-catenin (orange). Two cells, on the upper right (encircled), demonstrate an exaggerated junction with very high -catenin levels. These cells, as shown in the inset, were transfected with a GFP fusion construct of Dia1 (green) along with a constitutively active RhoA mutant, RhoA-V14. GFP-Dia1 localizes to adherens junctions and to the tips of filopodia produced along the periphery of the transfected cells. See article by L. Carramusa et al. (p. 3870).
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