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About the Cover
Cover: DAPI-stained dividing Euplotes aediculatus cell showing the large dividing macronucleus. This ciliated protozoa contains two types of nuclei within one cell: a large DNA-rich macronucleus and diploid micronuclei. The DNA in the macronucleus occurs in short 'gene-sized' DNA molecules, each of which is terminated by telomeric sequences. Owing to the high concentration of telomeres in its macronucleus, the E. aediculatus cell is an attractive model system in which to study telomere structure and telomere replication. M. Möllenbeck et al. (pp. 1757-1761) report that the biological function of a telomerase-associated protein is to anchor the enzyme in the replication factory of the macronucleus. This is the first study of the biological function of a telomerase-associated protein outside yeast.
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