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Almeida, E. A., Huovila, A. P., Sutherland, A. E., Stephens, L. E., Calarco, P. G., Shaw, L. M., Mercurio, A. M., A. Sonnenberg, Primakoff, P. and Myles, D. G (1995). Mouse egg integrin alpha 6 beta 1 functions as a sperm receptor. Cell 81, 1095-1104.[Medline]

Amour, A., Knight, C. G., Webster, A., Slocombe, P. M., Stephens, P. E., Knauper, V., Docherty, A. J. and Murphy, G (2000). The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3. FEBS Lett 473, 275-279.[Medline]

Amour, A., Slocombe, P. M., Webster, A., Butler, M., Knight, C. G., Smith,B. J., Stephens, P. E., Shelley, C., Hutton, M., Knauper, V., Docherty, A.J. and Murphy, G (1998). TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3. FEBS Lett 435, 39-44.[Medline]

Arribas, J., Coodly, L., Vollmer, P., Kishimoto, T. K., Rose-John, S. and Massague, J (1996). Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors. J. Biol. Chem 271, 11376-11382.[Abstract/Free Full Text]

Black, R. A., Rauch, C. T., Kozlosky, C. J., Peschon, J. J., Slack, J. L., Wolfson, M. F., Castner, B. J., Stocking, K. L., Reddy, P., Srinivasan, S., Nelson, N., Boiani, N., Schooley, K. A., Gerhart, M., Davis, R., Fitzner, J. N., Johnson, R. S., Paxton, R. J., March, C. J. and Cerretti, D. P (1997). A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 385, 729-733.[Medline]

Blobel, C. P (1997). Metalloprotease-disintegrins: links to cell adhesion and cleavage of TNF alpha and Notch. Cell 90, 589-592.[Medline]

Bond, M., Murphy, G., Bennett, M. R., Amour, A., Knaeuper, V., Newby, A. C. and Baker, A. H (2000). Localisation of the death domain of TIMP-3 to the N terminus: metalloproteinase inhibition is associated with pro-apoptotic activity. J. Biol. Chem 275, 41358-41363.[Abstract/Free Full Text]

Borland, G., Murphy, G. and Ager, A (1999). Tissue inhibitor of metalloproteinases-3 inhibits shedding of L-selectin from leukocytes. J. Biol. Chem 274, 2810-2815.[Abstract/Free Full Text]

Bosenberg, M. W. and Massague, J (1993). Juxtacrine cell signaling molecules. Curr. Opin. Cell Biol 5, 832-838.[Medline]

Carpenter, G (1999). Employment of the epidermal growth factor receptor in growth factor-independent signaling pathways. J. Cell Biol 146, 697-702.[Abstract/Free Full Text]

Cunnick, J. M., Dorsey, J. F., Standley, T., Turkson, J., Kraker, A. J., Fry, D. W., Jove, R. and Wu,J (1998). Role of tyrosine kinase activity of epidermal growth factor receptor in the lysophosphatidic acid-stimulated mitogen-activated protein kinase pathway. J. Biol. Chem 273, 14468-14475.[Abstract/Free Full Text]

Della Rocca, G. J., Maudsley, S., Daaka, Y., Lefkowitz, R. J. and Luttrell, L. M (1999). Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases. J. Biol. Chem 274, 13978-13984.[Abstract/Free Full Text]

Fan, H. and Derynck, R (1999). Ectodomain shedding of TGF-alpha and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. EMBO J 18, 6962-6972.[Medline]

Fitzgerald, M. L., Wang, Z., Park, P. W., Murphy, G. and Bernfield, M (2000). Shedding of syndecan-1 and-4 ectodomains is regulated by multiple signaling pathways and mediated by a TIMP-3-sensitive metalloproteinase. J. Cell Biol 148, 811-824.[Abstract/Free Full Text]

Galvani, A. P., Cristiani, C., Carpinelli, P., Landonio, A. and Bertolero, F (1995). Suramin modulates cellular levels of hepatocyte growth factor receptor by inducing shedding of a soluble form. Biochem. Pharmacol 50, 959-966.[Medline]

Gechtman, Z., Alonso, J. L., Raab, G., Ingber, D. E. and Klagsbrun, M (1999). The shedding of membrane-anchored heparin-binding epidermal-like growth factor is regulated by the Raf/mitogen-activated protein kinase cascade and by cell adhesion and spreading. J. Biol. Chem 274, 28828-28835.[Abstract/Free Full Text]

Giordano, S., Di Renzo, M. F., Narsimhan, R. P., Cooper, C. S., Rosa, C. and Comoglio, P. M (1989). Biosynthesis of the protein encoded by the c-met proto-oncogene. Oncogene 4, 1383-1388.[Medline]

Hargreaves, P. G., Wang, F., Antcliff, J., Murphy, G., Lawry, J., Russell, R. G. and Croucher, P. I (1998). Human myeloma cells shed the interleukin-6 receptor: inhibition by tissue inhibitor of metalloproteinase-3 and a hydroxamate-based metalloproteinase inhibitor. Br. J. Haematol 101, 694-702.[Medline]

Hooper, N. M., Karran, E. H. and Turner, A. J (1997). Membrane protein secretases. Biochem. J 321, 265-279.

Iba, K., Albrechtsen, R., Gilpin, B. J., Loechel, F. and Wewer, U. M (1999). Cysteine-rich domain of human ADAM 12 (meltrin alpha) supports tumor cell adhesion. Am. J. Pathol 154, 1489-1501.[Abstract/Free Full Text]

Izumi, Y., Hirata, M., Hasuwa, H., Iwamoto, R., Umata, T., Miyado, K., Tamai, Y., Kurisaki, T., Sehara-Fujisawa, A., Ohno, S. and Mekada, E (1998). A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. EMBO J 17, 7260-7272.[Medline]

Jeffers, M., Taylor, G. A., Weidner, K. M., Omura, S. and Vande Woude, G. F (1997). Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway. Mol. Cell Biol 17, 799-808.[Abstract]

Levitzki, A. and Gazit, A (1995). Tyrosine kinase inhibition: an approach to drug development. Science 267, 1782-1788.[Abstract/Free Full Text]

Madge, L. A., Sierra-Honigmann, M. R. and Pober, J. S (1999). Apoptosis-inducing agents cause rapid shedding of tumor necrosis factor receptor 1 (TNFR1). A nonpharmacological explanation for inhibition of TNF-mediated activation. J. Biol. Chem 274, 13643-13649.[Abstract/Free Full Text]

Moolenaar, W. H., Kranenburg, O., Postma, F. R. and Zondag, G. C (1997). Lysophosphatidic acid: G-protein signalling and cellular responses. Curr. Opin. Cell Biol 9, 168-173.[Medline]

Moro, L., Venturino, M., Bozzo, C., Silengo, L., Altruda, F., Beguinot, L., Tarone, G. and Defilippi, P (1998). Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival. EMBO J 17, 6622-6632.[Medline]

Moss, M. L., Jin, S. L., Milla, M. E., Bickett, D. M., Burkhart, W., Carter, H. L., Chen, W. J., Clay, W. C., Didsbury, J. R., Hassler, D. et al (1997). Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. Nature 385, 733-736.[Medline]

Nath, D., Slocombe, P. M., Stephens, P. E., Warn, A., Hutchinson, G. R., Yamada, K. M., Docherty, A. J. and Murphy, G (1999). Interaction of metargidin (ADAM-15) with alphavbeta3 and alpha5beta1 integrins on different haemopoietic cells. J. Cell Sci 112, 579-587.[Abstract]

Nath, D., Slocombe, P. M., Webster, A., Stephens, P. E., Docherty, A. J. and Murphy, G (2000). Meltrin gamma (ADAM-9) mediates cellular adhesion through alpha(6)beta(1)integrin, leading to a marked induction of fibroblast cell motility. J. Cell Sci 113, 2319-2328.[Abstract]

Peschon, J. J., Slack, J. L., Reddy, P., Stocking, K. L., Sunnarborg, S. W., Lee, D. C., Russell, W. E., Castner, B. J., Johnson, R. S., Fitzner, J. N. et al (1998). An essential role for ectodomain shedding in mammalian development. Science 282, 1281-1284.[Abstract/Free Full Text]

Prenzel, N., Zwick, E., Daub, H., Leserer, M., Abraham, R., Wallasch, C. and Ullrich, A (1999). EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402, 884-888.[Medline]

Schlondorff, J. and Blobel, C. P (1999). Metalloprotease-disintegrins:modular proteins capable of promoting cell-cell interactions and triggeringsignals by protein-ectodomain shedding. J. Cell Sci 112, 3603-3617.[Abstract]

Sibilia, M., J. P. Steinbach, L. Stingl, A. Aguzzi and E. F. Wagner (1998). A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor. EMBO J 17, 719-731.[Medline]

Sibilia, M. and Wagner, E. F (1995). Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269, 234-238.[Abstract/Free Full Text]

Subramanian, S. V., Fitzgerald, M. L. and Bernfield, M (1997). Regulated shedding of syndecan-1 and-4 ectodomains by thrombin and growth factor receptor activation. J. Biol. Chem 272, 14713-14720.[Abstract/Free Full Text]

Werb, Z. and Yan,Y (1998). A cellular striptease act. Science 282, 1279-1280.[Free Full Text]

Yabkowitz, R., Meyer, S., Black, T., Elliott, G., Merewether L. A., andYamane, H. K (1999). Inflammatory cytokines and vascular endothelial growth factor stimulate the release of soluble tie receptor from human endothelial cells via metalloprotease activation. Blood 93, 1969-1979.[Abstract/Free Full Text]

Yee, N. S., Langen, H. and Besmer, P (1993). Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells. J. Biol. Chem 268, 14189-14201.[Abstract/Free Full Text]

Zhang, X. P., Kamata, T., Yokoyama, K., Puzon-McLaughlin, W. and Takada, Y (1998). Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3. J. Biol. Chem 27, 3-.




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