Characterization and chromosomal localization of JAM-1, a platelet receptor for a stimulatory monoclonal antibody

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Naik, U. P.
	Articles by Spychala, J.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Naik, U. P.
	Articles by Spychala, J.

Baldwin, H. S., Shen, H. M., Yan, H. C., DeLisser, H. M., Chung, A., Mickanin, C., Trask, T., Kirschbaum, N. E., Newman, P. J., Albelda, S. M. et al (1994). Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development 120, 2539-2553.[Abstract/Free Full Text]

Beardsley, D. S (1990). Platelet membrane glycoproteins: role in primary hemostasis and component antigens. Yale J. Biol. Med 63, 469-475.[Medline]

Buck, C. A., Baldwin, H. S., DeLisser, H., Mickanin, C., Shen, H. M., Kennedy, G., Chen, A., Edelman, J. M. and Albelda, S. M (1993). Cell adhesion receptors and early mammalian heart development: an overview. C R Acad. Sci. III 316, 838-859.[Medline]

Carroll, R. C., Worthington, R. E. and Boucheix, C (1990). Stimulus-response coupling in human platelets activated by monoclonal antibodies to the CD9 antigen, a 24 kDa surface-membrane glycoprotein. Biochem. J 266, 527-535.[Medline]

Celi, A., Lorenzet, R., Furie, B. and Furie, B. C (1997). Platelet-leukocyte-endothelial cell interaction on the blood vessel wall. Semin. Hematol 34, 327-335.[Medline]

Chiba, R., Nakagawa, N., Kurasawa, K., Tanaka, Y., Saito, Y. and Iwamoto, I (1999). Ligation of CD31 (PECAM-1) on endothelial cells increases adhesive function of alphavbeta3 integrin and enhances beta1 integrin-mediated adhesion of eosinophils to endothelial cells. Blood 94, 1319-1329.[Abstract/Free Full Text]

Cunningham, S. A., Arrate, M. P., Rodriguez, J. M., Bjercke, R. J., Vanderslice, P., Morris, A. P. and Brock, T. A (2000). A novel protein with homology to the junctional adhesion molecule. Characterization of leukocyte interactions. J. Biol. Chem 275, 34750-34756.[Abstract/Free Full Text]

de Fougerolles, A. R. and Springer, T. A (1992). Intercellular adhesion molecule 3, a third adhesion counter-receptor for lymphocyte function-associated molecule 1 on resting lymphocytes. J. Exp. Med 175, 185-190.[Abstract/Free Full Text]

Dejana, E., Corada, M. and Lampugnani, M. G (1995). Endothelial cell-to-cell junctions. FASEB J 9, 910-918.[Abstract]

Del Maschio, A., De Luigi, A., Martin-Padura, I., Brockhaus, M., Bartfai, T., Fruscella, P., Adorini, L., Martino, G., Furlan, R., De Simoni, M. G. et al (1999). Leukocyte recruitment in the cerebrospinal fluid of mice with experimental meningitis is inhibited by an antibody to junctional adhesion molecule (JAM). J. Exp. Med 190, 1351-1356.[Abstract/Free Full Text]

Deng, X., Moran, J., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Primakoff, P. and Martin-DeLeon, P. A (1997). The mouse Spam1 maps to proximal chromosome 6 and is a candidate for the sperm dysfunction in Rb(6.16)24Lub and Rb(6.15)1Ald heterozygotes. Mamm. Genome 8, 94-97.[Medline]

Etzioni, A (1996). Adhesion molecules\320their role in health and disease. Pediatr. Res 39, 191-198.[Medline]

Fawcett, J., Holness, C. L., Needham, L. A., Turley, H., Gatter, K. C., Mason, D. Y. and Simmons, D. L (1992). Molecular cloning of ICAM-3, a third ligand for LFA-1, constitutively expressed on resting leukocytes. Nature 360, 481-484.[Medline]

Gurubhagavatula, I., Amrani, Y., Pratico, D., Ruberg, F. L., Albelda, S. M. and Panettieri, R. A., Jr (1998). Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release. J. Clin. Invest 101, 212-222.[Medline]

Harpaz, Y. and Chothia, C (1994). Many of the immunoglobulin superfamily domains in cell adhesion molecules and surface receptors belong to a new structural set which is close to that containing variable domains. J. Mol. Biol 238, 528-539.[Medline]

Jackson, D. E., Loo, R. O., Holyst, M. T. and Newman, P. J (1997). Identification and characterization of functional cation coordination sites in platelet endothelial cell adhesion molecule-1. Biochemistry 36, 9395-9404.[Medline]

Jackson, D. E., Ward, C. M., Wang, R. and Newman, P. J (1997). The protein-tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1-and integrin-mediated cellular signaling. J. Biol. Chem 272, 6986-6993.[Abstract/Free Full Text]

Jennings, L. K., Phillips, D. R. and Walker, W. S (1985). Monoclonal antibodies to human platelet glycoprotein IIb beta that initiate distinct platelet responses. Blood 65, 1112-1119.[Abstract/Free Full Text]

Kornecki, E., Walkowiak, B., Naik, U. P. and Ehrlich, Y. H (1990). Activation of human platelets by a stimulatory monoclonal antibody. J. Biol. Chem 265, 10042-10048.[Abstract/Free Full Text]

Liu, Y., Nusrat, A., Schnell, F. J., Reaves, T. A., Walsh, S., Pochet, M. and Parkos, C. A (2000). Human junction adhesion molecule regulates tight junction resealing in epithelia. J. Cell Sci 113, 2363-2374.[Abstract]

Martin-Padura, I., Lostaglio, S., Schneemann, M., Williams, L., Romano, M., Fruscella, P., Panzeri, C., Stoppacciaro, A., Ruco, L., Villa, A. et al (1998). Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J. Cell Biol 142, 117-127.[Abstract/Free Full Text]

McMillan, R (2000). The pathogenesis of chronic immune (idiopathic) thrombocytopenic purpura. Semin. Hematol 37, 5-9.[Medline]

Muller, W. A (1995). The role of PECAM-1 (CD31) in leukocyte emigration: studies in vitro and in vivo. J. Leukocyte Biol 57, 523-528.[Abstract]

Nagle, D. L., Martin-DeLeon, P., Hough, R. B. and Bucan, M (1994). Structural analysis of chromosomal rearrangements associated with the developmental mutations Ph, W19H, and Rw on mouse chromosome 5. Proc. Natl. Acad. Sci. USA 91, 7237-7241.[Abstract/Free Full Text]

Naik, U. P., Kornecki, E. and Ehrlich, Y. H (1991). Phosphorylation and dephosphorylation of human platelet surface proteins by an ecto-protein kinase/phosphatase system. Biochim. Biophys. Acta 1092, 256-264.[Medline]

Naik, U. P., Ehrlich, Y. H. and Kornecki, E (1995). Mechanisms of platelet activation by a stimulatory antibody: cross-linking of a novel platelet receptor for monoclonal antibody F11 with the FcRII receptor. Biochem. J 310, 155-162.

Newman, P. J., Hillery, C. A., Albrecht, R., Parise, L. V., Berndt, M. C., Mazurov, A. V., Dunlop, L. C., Zhang, J. and Rittenhouse, S. E (1992). Activation-dependent changes in human platelet PECAM-1: phosphorylation, cytoskeletal association, and surface membrane redistribution. J. Cell Biol 119, 239-246.[Abstract/Free Full Text]

Ozaki, H., Ishii, K., Horiuchi, H., Arai, H., Kawamoto, T., Okawa, K., Iwamatsu, A. and Kita, T (1999). Cutting edge: combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cells. J. Immunol 163, 553-557.[Abstract/Free Full Text]

Ozaki, H., Ishii, K., Arai, H., Horiuchi, H., Kawamoto, T., Suzuki, H. and Kita, T (2000). Junctional adhesion molecule (JAM) is phosphorylated by protein kinase C upon platelet activation. Biochem. Biophys. Res. Commun 276, 873-878.[Medline]

Palmeri, D., van Zante, A., Huang, C. C., Hemmerich, S. and Rosen, S. D (2000). Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells. J. Biol. Chem 275, 19139-19145.[Abstract/Free Full Text]

Perutelli, P. and Mori, P. G (1993). Activation of human platelets by monoclonal antibodies. Haematologica 78, 172-177.[Medline]

Rahuel, C., Le Van Kim, C., Mattei, M. G., Cartron, J. P. and Colin, Y (1996). A unique gene encodes spliceoforms of the B-cell adhesion molecule cell surface glycoprotein of epithelial cancer and of the Lutheran blood group glycoprotein. Blood 88, 1865-1872.[Abstract/Free Full Text]

Rosales, C., O'Brien, V., Kornberg, L. and Juliano, R (1995). Signal transduction by cell adhesion receptors. Biochim. Biophys. Acta 1242, 77-98.[Medline]

Scott, J. L., Dunn, S. M., Jin, B., Hillam, A. J., Walton, S., Berndt, M. C., Murray, A. W., Krissansen, G. W. and Burns, G. F (1989). Characterization of a novel membrane glycoprotein involved in platelet activation. J. Biol. Chem 264, 13475-13482.[Abstract/Free Full Text]

Sobocka, M. B., Sobocki, T., Banerjee, P., Weiss, C., Rushbrook, J. I., Norin, A. J., Hartwig, J., Salifu, M. O., Markell, M. S., Babinska, A. et al (2000). Cloning of the human platelet F11 receptor: a cell adhesion molecule member of the immunoglobulin superfamily involved in platelet aggregation. Blood 95, 2600-2609.[Abstract/Free Full Text]

Spychala, J., Datta, N. S., Takabayashi, K., Datta, M., Fox, I. H., Gribbin, T. and Mitchell, B. S (1996). Cloning of human adenosine kinase cDNA: sequence similarity to microbial ribokinases and fructokinases. Proc. Natl. Acad. Sci. USA 93, 1232-1237.[Abstract/Free Full Text]

Suter, D. M., Errante, L. D., Belotserkovsky, V. and Forscher, P (1998). The Ig superfamily cell adhesion molecule, apCAM, mediates growth cone steering by substrate-cytoskeletal coupling. J. Cell Biol 141, 227-240.[Abstract/Free Full Text]

Takaishi, K., Sasaki, T., Kotani, H., Nishioka, H. and Takai, Y (1997). Regulation of cell-cell adhesion by rac and rho small G proteins in MDCK cells. J. Cell Biol 139, 1047-1059.[Abstract/Free Full Text]

Vaporciyan, A. A., DeLisser, H. M., Yan, H. C., Mendiguren, II, Thom, S. R., Jones, M. L., Ward, P. A. and Albelda, S. M (1993). Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science 262, 1580-1582.[Abstract/Free Full Text]

Varon, D., Jackson, D. E., Shenkman, B., Dardik, R., Tamarin, I., Savion, N. and Newman, P. J (1998). Platelet/endothelial cell adhesion molecule-1 serves as a costimulatory agonist receptor that modulates integrin-dependent adhesion and aggregation of human platelets. Blood 91, 500-507.[Abstract/Free Full Text]

Vazeux, R., Hoffman, P. A., Tomita, J. K., Dickinson, E. S., Jasman, R. L., St. John, T. and Gallatin, W. M (1992). Cloning and characterization of a new intercellular adhesion molecule ICAM-R. Nature 360, 485-488.[Medline]

Wadenvik, H., Stockelberg, D. and Hou, M (1998). Platelet proteins as autoantibody targets in idiopathic thrombocytopenic purpura. Acta Paediatr. Suppl 424, 26-36.[Medline]

Wahl, S. M., Feldman, G. M. and McCarthy, J. B (1996). Regulation of leukocyte adhesion and signaling in inflammation and disease. J. Leukocyte Biol 59, 789-796.[Abstract]

Walsh, F. S. and Doherty, P (1997). Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance. Annu. Rev. Cell Dev. Biol 13, 425-456.[Medline]

Wang, F., Naik, U. P., Ehrlich, Y. H., Osada, S., Ohno, S. and Kornecki, E (1995). Stimulatory antibody-induced activation and selective translocation of protein kinase C isoenzymes in human platelets. Biochem. J 311, 401-406.

Williams, A. F (1987). A year in the life of the immunoglobulin superfamily. Immunol. Today 8, 298-303.

Williams, A. F. and Barclay, A. N (1988). The Immunoglobulin superfamily-domains for surface recognition. Annu. Rev. immunol 6, 381-405.[Medline]

Williams, L. A., Martin-Padura, I., Dejana, E., Hogg, N. and Simmons, D. L (1999). Identification and characterisation of human junctional adhesion molecule (JAM). Mol. Immunol 36, 1175-1188.[Medline]

Worthington, R. E., Carroll, R. C. and Boucheix, C (1990). Platelet activation by CD9 monoclonal antibodies is mediated by the Fc gamma II receptor. Br. J. Haematol 74, 216-222.[Medline]

Wu, X. W. and Lian, E. C (1997). Binding properties and inhibition of platelet aggregation by a monoclonal antibody to CD31 (PECAM-1). Arterioscler. Thromb. Vasc. Biol 17, 3154-3158.[Abstract/Free Full Text]

Wuthrich, R. P (1992). Monoclonal antibodies targeting murine LFA-1 induce LFA-1/ICAM-1-independent homotypic lymphocyte aggregation. Cell Immunol 144, 22-31.[Medline]

This article has been cited by other articles:

M. U. Naik, T. U. Naik, A. T. Suckow, M. K. Duncan, and U. P. Naik
Attenuation of Junctional Adhesion Molecule-A Is a Contributing Factor for Breast Cancer Cell Invasion
Cancer Res., April 1, 2008; 68(7): 2194 - 2203.
[Abstract] [Full Text] [PDF]

L. T. Braiterman, S. Heffernan, L. Nyasae, D. Johns, A. P. See, R. Yutzy, A. McNickle, M. Herman, A. Sharma, U. P. Naik, et al.
JAM-A is both essential and inhibitory to development of hepatic polarity in WIF-B cells
Am J Physiol Gastrointest Liver Physiol, February 1, 2008; 294(2): G576 - G588.
[Abstract] [Full Text] [PDF]

V. G. Cooke, M. U. Naik, and U. P. Naik
Fibroblast Growth Factor-2 Failed to Induce Angiogenesis in Junctional Adhesion Molecule-A-Deficient Mice
Arterioscler. Thromb. Vasc. Biol., September 1, 2006; 26(9): 2005 - 2011.
[Abstract] [Full Text] [PDF]

M. U. Naik and U. P. Naik
Junctional adhesion molecule-A-induced endothelial cell migration on vitronectin is integrin {alpha}v{beta}3 specific
J. Cell Sci., February 1, 2006; 119(3): 490 - 499.
[Abstract] [Full Text] [PDF]

S. Sheikh, R. S. Parhar, R. Bakheet, S. Saleh, K. Collison, and F. Al-Mohanna
Immobilization of rolling NK cells on platelet-borne P-selectin under flow by proinflammatory stimuli, interleukin-12, and leukotriene B4
J. Leukoc. Biol., September 1, 2004; 76(3): 603 - 608.
[Abstract] [Full Text] [PDF]

K. Ebnet, A. Suzuki, S. Ohno, and D. Vestweber
Junctional adhesion molecules (JAMs): more molecules with dual functions?
J. Cell Sci., January 1, 2004; 117(1): 19 - 29.
[Abstract] [Full Text] [PDF]

M. U. Naik, D. Vuppalanchi, and U. P. Naik
Essential Role of Junctional Adhesion Molecule-1 in Basic Fibroblast Growth Factor-Induced Endothelial Cell Migration
Arterioscler. Thromb. Vasc. Biol., December 1, 2003; 23(12): 2165 - 2171.
[Abstract] [Full Text] [PDF]

M. U. Naik and U. P. Naik
Calcium-and integrin-binding protein regulates focal adhesion kinase activity during platelet spreading on immobilized fibrinogen
Blood, November 15, 2003; 102(10): 3629 - 3636.
[Abstract] [Full Text] [PDF]

M. U. Naik, S. A. Mousa, C. A. Parkos, and U. P. Naik
Signaling through JAM-1 and {alpha}v{beta}3 is required for the angiogenic action of bFGF: dissociation of the JAM-1 and {alpha}v{beta}3 complex
Blood, September 15, 2003; 102(6): 2108 - 2114.
[Abstract] [Full Text] [PDF]

U. P. Naik and M. U. Naik
Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen
Blood, August 15, 2003; 102(4): 1355 - 1362.
[Abstract] [Full Text] [PDF]

A. E. Prota, J. A. Campbell, P. Schelling, J. C. Forrest, M. J. Watson, T. R. Peters, M. Aurrand-Lions, B. A. Imhof, T. S. Dermody, and T. Stehle
Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding
PNAS, April 29, 2003; 100(9): 5366 - 5371.
[Abstract] [Full Text] [PDF]

A. R. Burns, C. W. Smith, and D. C. Walker
Unique Structural Features That Influence Neutrophil Emigration Into the Lung
Physiol Rev, April 1, 2003; 83(2): 309 - 336.
[Abstract] [Full Text] [PDF]

S. Santoso, U. J.H. Sachs, H. Kroll, M. Linder, A. Ruf, K. T. Preissner, and T. Chavakis
The Junctional Adhesion Molecule 3 (JAM-3) on Human Platelets is a Counterreceptor for the Leukocyte Integrin Mac-1
J. Exp. Med., September 2, 2002; 196(5): 679 - 691.
[Abstract] [Full Text] [PDF]

M. Aurrand-Lions, C. Johnson-Leger, C. Wong, L. Du Pasquier, and B. A. Imhof
Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members
Blood, December 15, 2001; 98(13): 3699 - 3707.
[Abstract] [Full Text] [PDF]

S. Tsuji, J. Uehori, M. Matsumoto, Y. Suzuki, A. Matsuhisa, K. Toyoshima, and T. Seya
Human Intelectin Is a Novel Soluble Lectin That Recognizes Galactofuranose in Carbohydrate Chains of Bacterial Cell Wall
J. Biol. Chem., June 22, 2001; 276(26): 23456 - 23463.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Naik, U. P.

Articles by Spychala, J.

Search for Related Content

PubMed

PubMed Citation

Articles by Naik, U. P.

Articles by Spychala, J.

				L. T. Braiterman, S. Heffernan, L. Nyasae, D. Johns, A. P. See, R. Yutzy, A. McNickle, M. Herman, A. Sharma, U. P. Naik, et al. JAM-A is both essential and inhibitory to development of hepatic polarity in WIF-B cells Am J Physiol Gastrointest Liver Physiol, February 1, 2008; 294(2): G576 - G588. [Abstract] [Full Text] [PDF]

				V. G. Cooke, M. U. Naik, and U. P. Naik Fibroblast Growth Factor-2 Failed to Induce Angiogenesis in Junctional Adhesion Molecule-A-Deficient Mice Arterioscler. Thromb. Vasc. Biol., September 1, 2006; 26(9): 2005 - 2011. [Abstract] [Full Text] [PDF]

				M. U. Naik and U. P. Naik Junctional adhesion molecule-A-induced endothelial cell migration on vitronectin is integrin {alpha}v{beta}3 specific J. Cell Sci., February 1, 2006; 119(3): 490 - 499. [Abstract] [Full Text] [PDF]

				S. Sheikh, R. S. Parhar, R. Bakheet, S. Saleh, K. Collison, and F. Al-Mohanna Immobilization of rolling NK cells on platelet-borne P-selectin under flow by proinflammatory stimuli, interleukin-12, and leukotriene B4 J. Leukoc. Biol., September 1, 2004; 76(3): 603 - 608. [Abstract] [Full Text] [PDF]

				K. Ebnet, A. Suzuki, S. Ohno, and D. Vestweber Junctional adhesion molecules (JAMs): more molecules with dual functions? J. Cell Sci., January 1, 2004; 117(1): 19 - 29. [Abstract] [Full Text] [PDF]

				M. U. Naik, D. Vuppalanchi, and U. P. Naik Essential Role of Junctional Adhesion Molecule-1 in Basic Fibroblast Growth Factor-Induced Endothelial Cell Migration Arterioscler. Thromb. Vasc. Biol., December 1, 2003; 23(12): 2165 - 2171. [Abstract] [Full Text] [PDF]

				M. U. Naik and U. P. Naik Calcium-and integrin-binding protein regulates focal adhesion kinase activity during platelet spreading on immobilized fibrinogen Blood, November 15, 2003; 102(10): 3629 - 3636. [Abstract] [Full Text] [PDF]

				M. U. Naik, S. A. Mousa, C. A. Parkos, and U. P. Naik Signaling through JAM-1 and {alpha}v{beta}3 is required for the angiogenic action of bFGF: dissociation of the JAM-1 and {alpha}v{beta}3 complex Blood, September 15, 2003; 102(6): 2108 - 2114. [Abstract] [Full Text] [PDF]

				U. P. Naik and M. U. Naik Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen Blood, August 15, 2003; 102(4): 1355 - 1362. [Abstract] [Full Text] [PDF]

				A. E. Prota, J. A. Campbell, P. Schelling, J. C. Forrest, M. J. Watson, T. R. Peters, M. Aurrand-Lions, B. A. Imhof, T. S. Dermody, and T. Stehle Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding PNAS, April 29, 2003; 100(9): 5366 - 5371. [Abstract] [Full Text] [PDF]

				A. R. Burns, C. W. Smith, and D. C. Walker Unique Structural Features That Influence Neutrophil Emigration Into the Lung Physiol Rev, April 1, 2003; 83(2): 309 - 336. [Abstract] [Full Text] [PDF]

				S. Santoso, U. J.H. Sachs, H. Kroll, M. Linder, A. Ruf, K. T. Preissner, and T. Chavakis The Junctional Adhesion Molecule 3 (JAM-3) on Human Platelets is a Counterreceptor for the Leukocyte Integrin Mac-1 J. Exp. Med., September 2, 2002; 196(5): 679 - 691. [Abstract] [Full Text] [PDF]

				M. Aurrand-Lions, C. Johnson-Leger, C. Wong, L. Du Pasquier, and B. A. Imhof Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members Blood, December 15, 2001; 98(13): 3699 - 3707. [Abstract] [Full Text] [PDF]

				S. Tsuji, J. Uehori, M. Matsumoto, Y. Suzuki, A. Matsuhisa, K. Toyoshima, and T. Seya Human Intelectin Is a Novel Soluble Lectin That Recognizes Galactofuranose in Carbohydrate Chains of Bacterial Cell Wall J. Biol. Chem., June 22, 2001; 276(26): 23456 - 23463. [Abstract] [Full Text] [PDF]