VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells

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Baldin, V., Roman, A.-M., Bose-Biern, C., Amalric, F. and Bouche, G (1990). Translocation of bFGF to the nucleus in G1phase cell cycle specific in bovine aortic endothelial cells. EMBO J 9, 1511-1517.[Medline]

Banai, S. D., Shweiki, A., Pinson, M., Chandra, G., Lazarovici, G. and Keshet, E (1994). Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis. Cardiovasc. Res 28, 1176-1179.[Abstract/Free Full Text]

Bouche, G., Gas, N., Prats, H., Baldin, V., Tauber, J.-P., Teissie, J. and Amalric, F (1989). Basic fibroblast growth factor enters the nucleolus and stimulates the transcription of ribosomal genes in ABAE cells undergoing G0to G1transition. Nucleic Acids Res 17, 6625-6636.[Abstract/Free Full Text]

Brock, T. A., Dvorak, H. F. and Senger, D. R (1991). Tumour secreted vascular permeability factor increase cytosolic Ca2+and von Willebrand factor release in human endothelial cells. Am. J. Pathol 138, 213-221.[Abstract]

Brook, P. C., Clark, R. A., F. and Cheresh, D. A (1994). Requirement of vascular integrinv 3 for angiogenesis. Science 264, 569-571.[Abstract/Free Full Text]

Camerer, E., Kolsto, A.-B. and Prydz, H (1996). Cell biology of tissue factor, the principle initiator of blood coagulation. Thromb. Res 81, 1-41.[Medline]

Carmeliet, P. and Collen, D (1997). Molecular analysis of blood vessel formation and disease. Am. J. Physiol 273, 2091-.

Clauss, M., Gerlach, H., Brett, J., Wang, F., Familetti, P. C., Pan, Y.-C., Olander, J. V., Connolly, D. T. and Stern, D (1990). Vascular permeability factor: a tumor derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration. J. Exp. Med 172, 1535-1545.[Abstract/Free Full Text]

Clauss, M., Weich, H., Breier, G., Knies, U. R. W., Waltenberger, J. and Risau, W (1996). The vascular endothelial growth factor receptor Flt-1 mediates biological activity. Implications for a functional role of placental growth factor in monocyte activation and chemotaxis. J. Biol. Chem 271, 17629-17634.[Abstract/Free Full Text]

de Vries, C., Escobedo, J. A., Houck, K., Ferrara, N. and Williams, L. T (1992). The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 255, 989-991.[Abstract/Free Full Text]

Dvorak, H. F., Brown, L. F., Detmar, M. and Dvorak, A. M (1995). Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am. J. Pathol 146, 1029-1039.[Abstract]

Evan, G. I. and Littlewood, T. D (1993). The role of c-myc in cell growth. Curr. Opin. Genet. Dev 3, 44-49.[Medline]

Ferrara, N. and Davis-Smyth, T (1997). The biology of vascular endothelial growth factor. Endocr. Rev 18, 4-25.[Abstract/Free Full Text]

Ferrara, N. and Henzel, W. J (1989). Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem. Biophys. Res. Commun 161, 851-859.[Medline]

Ferrara, N. and Keyt, B (1997). Vascular endothelial growth factor: basic biology and clinical implications. Experientia Supplementum 79, 209-232.

Folkman, J (1982). Angiogenesis: initiation and control. Ann. NY Acad. Sci 401, 212-227.[Medline]

Frank, S., Hubner, G., Breier, G., Longaker, M. T., Greenhalgh, D. G. and Wener, S (1995). Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing. J. Biol. Chem 270, 12607-12613.[Abstract/Free Full Text]

Greenberg, M. E., Greene, L. A. and Ziff, E. G (1985). Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells. J. Biol. Chem 260, 14101-14110.[Abstract/Free Full Text]

Harmey, J. H., Dimitriadis, E., Kay, E., Redmond, H. P. and Bouchier-Hayes, D (1998). Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1. Ann. Surg. Oncol 5, 271-278.[Abstract]

Hashimoto, E., Ogita, T., Nakaoka, T., Matsuoka, R., Takao, A. and Kira, Y (1994). Rapid induction of vascular endothelial growth factor expression by transient ischemia in rat heart. Am. J. Physiol 267, 1948-1954.

Imamura, T., Engleka, K., Zhan, X., Tokita, Y., Forough, R., Roeder, D., Jackson, A., Maier, J. A., Hla, T. and Maciag, T (1990). Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence. Science 249, 1567-70.[Abstract/Free Full Text]

Imamura, T., Oka, S., Tanahashi, T. and Okita, Y (1994). Cell cycle-dependent nuclear localization of exogenously added fibroblast growth factor-1 in BALB/c 3T3 and human vascular endothelial cells. Exp. Cell Res 215, 363-72.[Medline]

Kelly, K., Cochran, B. H., Stiles, C. D. and Leder, P (1983). Cell specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell 35, 603-610.[Medline]

Keyt, B. A., Berleau, L. T., Nguyen, H. V., Chen, H., Heinsohn, H., Vandlen, R. and Ferrara, N (1996). The carboxyl-terminal domain (111-165) of vascular endothelial growth factor is critical for its mitogenic potency. J. Biol. Chem 271, 7788-7795.[Abstract/Free Full Text]

Kim, J., Li, B., Weiner, J., Houch, K. and Ferrara, N (1992). The vascularendothelial cell growth factor family. Identification of biologically relevant regions by neutralizing monoclonal antibodies. Growth Factors 7, 53-64.[Medline]

Kimura, H (1993). Schwannoma-derived growth factor must be transported into the nucleus to exert its mitogenic activity. Proc. Natl. Acad. Sci. USA 90, 2165-2169.[Abstract/Free Full Text]

Lee, B. A., Maher, D. W., Hannink, M. and Donoghue, D. J (1987). Identification of a signal for nuclear targeting in Platelet-derived growth-factor-related molecules. Mol. Cell Biol 7, 3527-3537.[Abstract/Free Full Text]

Lenting, P. J., van Mourik, J. A. and Mertens, K (1998). The life cycle of coagulation factor VIII in view of its structure and function. Blood 92, 3983-3996.[Free Full Text]

Li, W., Fawcett, J., Widmer, H. R., Fielder, P. J., Rabkin, R. and Keller, G.-A (1997). Nuclear transport of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in opossum kidney cells. Endocrinology 138, 1763-1766.[Abstract/Free Full Text]

Li, W., Park, J. W., Nuijens, A., Sliwkowski, M. X. and Keller, G.-A (1996). Heregulin is rapidly translocated to the nucleus and its transport is correlated with c-myc induction in breast cancer cells. Oncogene 12, 2473-2477.[Medline]

Mandriota, S. J. and Pepper, M. S (1997). Vascular endothelial growth factor-induced in vitro angiogenesis and plasminogen activator expression are dependent on endogenous basic fibroblast growth factor. J. Cell Sci 110, 2293-2302.[Abstract]

Maynard, J. R., Dryer, B. E., Stemerman, M. E. and Pitlick, F. A (1977). Tissue factor coagulant activity of cultured human endothelial and smooth muscle cells and fibroblasts. Blood 50, 387-396.[Abstract/Free Full Text]

Mohle, R., Green, D., Moore, M. A., Nachman, R. L. and Rafii, S (1997). Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proc. Natl. Acad. Sci. USA 94, 663-668.[Abstract/Free Full Text]

Moroianu, J. and Riordan, J. F (1994). Nuclear translocation of angiogenin in proliferating endothelial cells is essential to its angiogenic activity. Proc. Natl. Acad. Sci. USA 91, 1677-1681.[Abstract/Free Full Text]

Mulder, A. B., Blom, N. R., Smit, J. W., Ruiters, M. H., van der Meer, J., Halie, M. R. and Bom, V. J (1995). Basal tissue factor expression in endothelial cell cultures is caused by contamination of smooth muscle cells. Reduction by using chymotrypsin instead of collagenase. Thromb. Res 80, 399-411.[Medline]

Muller, R., Bravo, R. and Burckhardt, J (1984). Induction of c-fos gene and protein by growth factors precedes activation of c-myc. Nature 312, 716-720.[Medline]

Pepper, M. S., Ferrara, N., Orci, L. and Montesano, R (1991). Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem. Biophys. Res. Commun 181, 902-906.[Medline]

Pepper, M. S., Ferrara, N., Orci, L. and Montesano, R (1992). Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro. Biochem. Biophys. Res. Commun 189, 824-831.[Medline]

Peters, K., DeVries, C. and Williams, L (1993). Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth. Proc. Natl. Acad. Sci. USA 90, 8915-8919.[Abstract/Free Full Text]

Poltrak, Z., Cohen, T., Sivan, R., Kandelis, Y., Spira, G., Vlodavsky, I., Keshet, E. and Neufeld, G (1997). VEGF145, a secreted vascular endothelial growth factor isoform that binds to extracellular matrix. J. Biol. Chem 272, 7151-7158.[Abstract/Free Full Text]

Reed, M. J. and Sage, E. H (1996). SPARC and the extracellular matrix: implication for cancer and wound repair. Curr. Top. Microbiol. Immunol 213, 81-94.

Roberts, G. W. and Palade, G. E (1995). Increased microvascular permeability and endothelial fenestration induced by vascular growth factor. J. Cell Sci 108, 2369-2379.[Abstract]

Schecter, A. D., Giesen, P. L. A., Taby, O., Rosenfield, C.-L., Rossikhina, M., Fyfe, B. S., Kohtz, D. S., Fallon, J. T., Nemerson, Y. and Taubman, M. B (1997). Tissue factor expression in human arterial smooth muscle cells. TF is present in three cellular pools after growth factor stimulation. J. Clin. Invest 100, 2276-2285.[Medline]

Schedlich, L. J., Young, T. F., Firth, S. M. and Baxter, R. C (1998). Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells. J. Biol. Chem 273, 18347-18352.[Abstract/Free Full Text]

Soker, S., Takashima, S., Miao, H. Q., Neufeld, G. and Klagsbrun, M (1998). Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92, 735-745.[Medline]

Stel, H. V., van der Kwast, T. H. and Veerman, E. C. I (1983). Detection of factor VIII/coagulant antigen in human liver tissue. Nature 303, 530-532.[Medline]

Terman, B., Khandke, L., Dougher-Vermazan, M., Maglione, D., Lassam, N. J., Gospodarowicz, D., Persico, M. G., Bohlen, P. and Eisinger, M (1994). VEGF receptor subtypes KDR and FLT1 show different sensitivities to heparin and placenta growth factor. Growth Factors 11, 187-195.[Medline]

Walicke, P. A. and Baird, A (1991). Internalization and processing of basic fibroblast growth factor by neurons and astrocytes. J. Neurosci 11, 2249-2258.[Abstract]

Walter, D. H., Hink, U., Asahara, T., Van Belle, E., Horowitz, J., Tsurumi, Y., Vandlen, R., Heinsohn, H., Keyt, B., Ferrara, N., Symes, J. F. and Isner, J. M (1996). The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation. Lab. Invest 74, 546-556.[Medline]

Walterberger, J., Claesson-Welsh, L., Siegbahn, A., Shibuya, M. and Heldin, C.-H (1994). Different signal transduction properties of KDR andFlt1, two receptors for vascular endothelial growth factor. J. Biol. Chem 269, 26988-26995.[Abstract/Free Full Text]

Webb, N. J. A., Bottomley, M. J., Watson, C. J. and Brenchley, P. E. C (1998). Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting: implications for measurement of circulating VEGF levels in clinical disease. Clin. Sci 94, 395-404.[Medline]

Wiedlocha, A., Falnes, P. O., Madshus, I. H., Sandvig, K. and Olsnes, S (1994). Dual mode of signal transduction by externally added acidic fibroblast growth factor. Cell 76, 1039-1051.[Medline]

Wimber, D. E. and Quastler, H. A (1963). 14C and 3H-thymidine double labeling technique in the study of cell proliferation in Tradescantia root tips. Exp. Cell Res 30, 8-22.

Wion, K. L., Kelly, D., Summerfield, J. A., Tuddenham, E. G. and Lawn, R. M (1985). Distribution of factor VIII mRNA and antigen in human liver and other tissues. Nature 317, 726-729.[Medline]

Zeytin, F. M., Rusk, S. F., A., B., Raymond, V., Leff, S. E. and Mandell, A. J (1988). Induction of c-fos, calcitonin gene expression, and acidic FGF production in a multipeptide-secreting neuroendocrine cell line. Endocrinology 122, 1114-1120.[Abstract]

Zucker, S., Mirza, H., Conner, C. E., Lorenz, A. F., Drews, M. H., Bahou, W. F. and Jesty, J (1998). Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation. Int. J. Cancer 75, 780-786.[Medline]

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