Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Sun, J.
	Articles by Albelda, S. M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Sun, J.
	Articles by Albelda, S. M.

Albelda, S. M., Oliver, L. H., Romer, L. H. and Buck, C. A (1990). EndoCAM: a novel endothelial cell-cell adhesion molecule. J. Cell Biol 110, 1227-1237.[Abstract/Free Full Text]

Albelda, S. M., Muller W. A., Buck, C. A. and Newman, P (1991). Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. J. Cell Biol 114, 1059-1068.[Abstract/Free Full Text]

Ayalon, O., Sabanai, H., Lampugnani, M. G., Dejana, E. and Geiger, B (1994). Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells. J. Cell Biol 126, 247-258.[Abstract/Free Full Text]

Cao, M. Y., Huber M., Beauchemin N., Famiglietti, J., Albelda, S. M. and Veillette, A (1998). Regulation of PECAM-1 tyrosine phosphorylation by the Src and Csk families of tyrosine protein kinases,. J. Biol. Chem 273, 15765-15762.[Abstract/Free Full Text]

Carpen, O., Pallai P., Staunton, D. and Springer, T (1992). Association of intercellular adhesion molecule-1 (ICAM-1) with actin-containing cytoskeleton and-actinin. J. Cell Biol 118, 1223-1234.[Abstract/Free Full Text]

Dejana, E (1996). Perspectives series: cell adhesion in vascular biology. J. Clin. Invest 98, 1949-1953.[Medline]

DeLisser, H. M., Muller, W., Newman, P., Buck, C. A. and Albelda, S. M (1993). PECAM-1 mediates heterophilic glycosaminoglycan-dependent cell-cell adhesion. J. Biol. Chem 258, 16307-16346.

DeLisser, H. M., Chilkotowsky J., Yan, H. C., Daise M. L., Buck, C. A. and Albelda, S. M (1994). Deletions in the cytoplasmic domain of platelet-endothelial cell adhesion molecule-1 (PECAM-1, CD31) result in changes in ligand binding properties. J. Cell Biol 124, 195-203.[Abstract/Free Full Text]

DeLisser, H. M., Christofidou-Solomidou, M., Strieter, R. M., Burdick, M. D., Robinson, C. S., Wexler, R. S., Kerr, J. S., Garlanda, C., Merwin, J. R., Madri, J. A. and Albelda, S. M (1997). Involvement of endothelial PECAM-1/CD31 in angiogenesis. Am. J. Pathol 151, 671-677.[Abstract]

Famiglietti, J., Sun, J., DeLisser, H. M. and Albelda, S. M (1997). Tyrosine residue in exon 14 of the cytoplasmic domain of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) regulates ligand binding specificity. J. Cell Biol 138, 1425-1435.[Abstract/Free Full Text]

Ferrero, E., Villa, A., Ferrero, M. E., Toninelli, E., Bender, J. R., Pardi, R. and Zocchi, M. R (1996). Tumor necrosis factor-induced vascular leakage involves PECAM1 phosphorylation. Cancer Res 56, 3211-3215.[Abstract/Free Full Text]

Gingell, D. and Owens, N (1992). How do cells sense and respond to adhesive contacts? Diffusion-trapping of laterally mobile membrane proteins at maturing adhesions may initiate signals leading to local cytoskeletal assembly response and lamella formation. J. Cell Sci 101, 255-266.[Free Full Text]

Gurubhagavatula, I., Amrani, Y., Pratico, D., Ruberg, F. L., Albelda, S. M. and Panettieri, R. A. Jr (1998). Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release. J. Clin. Invest 101, 212-222.[Medline]

Horton, R. M., Cai, Z., Ho, S. N. and Pease, L. R (1990). Gene splicing by overlap extension: Tailor-made genes using the polymerase chain reaction. BioTechniques 8, 528-535.[Medline]

Jackson, D. E., Kupcho, K. R. and Newman, P. J (1997). Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2. J. Biol. Chem 272, 24868-24875.[Abstract/Free Full Text]

Jackson, D. E., Ward, C. M., Wang, R. and Newman, P. J (1997). The protein-tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation. J. Biol. Chem 272, 6986-6993.[Abstract/Free Full Text]

Kirschbaum, N. E., Gumina, R. J. and Newman, P. J (1994). Organization of the gene for human platelet/endothelial cell adhesion molecule-1 (PECAM-1) reveals alternatively spliced isoforms and functionally complex cytoplasmic domain. Blood 84, 4028-4037.[Abstract/Free Full Text]

LaFlamme, S. E., Thomas, L. A., Yamada, S. S. and Yamada, K. M (1994). Single subunit chimeric integrins as mimics and inhibitors of endogenous integrin functions in receptor localization, cell spreading and migration, and matrix assembly. J. Cell Biol 126, 1287-1298.[Abstract/Free Full Text]

Liao, F., Ali, J., Green T. and Muller, W. A (1997). Soluble domain 1 platelet-endothelial cell adhesion molecule (PECAM) is sufficient to block transendothelial migration in vitro and in vivo. J. Exp. Med 185, 1349-1357.[Abstract/Free Full Text]

Liao, F., Schenkel, A. R. and Muller, W. A (1999). Transgeneic mice expressing different levels of soluble platelet/endothelial cell adhesion molecule-IgG display distinct inflammatory phenotypes. J. Immunol 163, 5640-5648.[Abstract/Free Full Text]

Lu, T. L., Barreuther, M., Davis, S. and Madri, J. A (1997). Platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) isphosphorylatable by C-SRC, binds SRC-SH2 domain and exhibits itam-like properties. J. Biol. Chem 272, 14442-14446.[Abstract/Free Full Text]

Masuda, M., Osawa, H. J., Shigematsu, N. and Fujiwara, K (1997). Platelet endothelial cell adhesion molecule-1 is a major SH-PTP2 binding protein in vascular endothelial cells. FEBS Lett 408, 331-336.[Medline]

Matsumura, T., Wolff, K. and Petzelbauer, P (1997). Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin. J. Immunol 158, 3408-3416.[Abstract]

Muller, W. A., Ratti, C. M., McDonnell, S. L. and Cohn, Z. A (1989). A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions. J. Exp. Med 170, 399-414.[Abstract/Free Full Text]

Muller, W. A., Weigl, S. A., Deng, X. and Phillips, D. M (1993). PECAM-1 is required for transendothelial migration of leukocytes. J. Exp. Med 178, 449-460.[Abstract/Free Full Text]

Newman, P. J (1997). Perspective Series: Cell Adhesion in vascular biology. The biology of PECAM-1,. J. Clin. Invest 99, 3-8.[Medline]

Newman, P. J (1999). Switched at birth \320 a new family for PECAM-1. J. Clin. Invest 103, 5-9.[Medline]

Newton, J. P., Buckley, C. D., Jones, E. Y. and Simmons, D. L (1997). Residues on both faces of the first immunoglobulin fold contribute to homophilic binding sites of PECAM-1/CD31. J. Biol. Chem 272, 20555-20563.[Abstract/Free Full Text]

Newton, J. P., Hunter, A. P., Simmons, D. L., Buckley, C. D. and Harvey, D. J (1999). CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated. Biochem. Biophys. Res. Commun 261, 283-291.[Medline]

Osawa, M. M., Harada, N., Lopes, R. B. and Fujiwara, K (1997). Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1) in mechanically stimulated vascular endothelial cells. Eur. J. Cell Biol 72, 229-237.[Medline]

Pinter, E., Barreuther, M., Lu, T., Imhof, B. A. and Madri, J. A (1997). Platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) tyrosine phosphorylation state changes during vasculogenesis in the murine conceptus. Am. J. Pathol 150, 1523-1529.[Abstract]

Romer, L. H., McLean, N. V., Yan, H. C., Daise, M., Sun, J. and DeLisser, H. M (1995). IFN-and TNF- induce redistribution of PECAM-1 (CD31) on human endothelial cells. J. Immunol 154, 6582-6592.[Abstract]

Sheibani, N., Newman, P. J. and Frazier, W. A (1997). Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis. Mol. Biol. Cell 8, 1329-1341.[Abstract]

Singer, S. J (1992). Intercellular communication and cell-cell adhesion. Science 255, 1671-1677.[Abstract/Free Full Text]

Smythe, W. R., Hwang, H. C., Amin, K. M., Eck, S. L., Davidson, B. L., Wilson, J. M., Kaiser, L. R. and Albelda, S. M (1994). Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVTk) gene to thoracic neoplasms: an effective in vitro drug sensitization system. Cancer Res 54, 2055-2059.[Abstract/Free Full Text]

Stappert, J. and Kemler. R (1993). Intracellular associations of adhesion molecules. Curr. Opin. Neurobiol 3, 60-66.[Medline]

Sun, J., Williams, J., Yan, H. C., Albelda, S. M. and DeLisser, H. M (1996). PECAM-1 homophilic adhesion is mediated by Ig-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. J. Biol. Chem 271, 18561-18570.[Abstract/Free Full Text]

Sun, Q. H., DeLisser, H. M., Zukowski, M. M., Paddock, C., Albelda, S. M. and Newman, P. J (1996). Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity. J. Biol. Chem 271, 11090-11098.[Abstract/Free Full Text]

Vaporciyan, A. A., DeLisser, H. M, Yan, H. C., Mendiguren, I. I., Thom, S. R., Jones, M. L., Ward, P. A. and Albelda, S. M (1993). Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science 262, 1580-1582.[Abstract/Free Full Text]

Yan, H. C., Baldwin, H. S., Sun, J., Buck, C. A., Albelda, S. M. and DeLisser, H. M (1995). Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1). J. Biol. Chem 270, 23672-23680.[Abstract/Free Full Text]

Yap, A. S., Niessen, C. M. and Gumbiner, B (1998). The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. J. Cell Biol 141, 779-789.[Abstract/Free Full Text]

Zocchi, M., Ferrero, E., Leone, B., Rovere, P., Bianchi, E., Toninelli, E. and Pardi, R (1996). CD31/PECAM-1-driven chemokine-independent transmigration of human T lymphocytes. Eur. J. Immunol 26, 759-767.[Medline]

This article has been cited by other articles:

C. Bergom, C. Paddock, C. Gao, T. Holyst, D. K. Newman, and P. J. Newman
An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling
J. Cell Sci., April 15, 2008; 121(8): 1235 - 1242.
[Abstract] [Full Text] [PDF]

C. Garnacho, V. Shuvaev, A. Thomas, L. McKenna, J. Sun, M. Koval, S. Albelda, V. Muzykantov, and S. Muro
RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1
Blood, March 15, 2008; 111(6): 3024 - 3033.
[Abstract] [Full Text] [PDF]

K. J. D. A. Excoffon, G. L. Traver, and J. Zabner
The Role of the Extracellular Domain in the Biology of the Coxsackievirus and Adenovirus Receptor
Am. J. Respir. Cell Mol. Biol., June 1, 2005; 32(6): 498 - 503.
[Abstract] [Full Text] [PDF]

P. L. W. Yun, A. A. Decarlo, C. C. Chapple, and N. Hunter
Functional Implication of the Hydrolysis of Platelet Endothelial Cell Adhesion Molecule 1 (CD31) by Gingipains of Porphyromonas gingivalis for the Pathology of Periodontal Disease
Infect. Immun., March 1, 2005; 73(3): 1386 - 1398.
[Abstract] [Full Text] [PDF]

M. Maas, M. Stapleton, C. Bergom, D. L. Mattson, D. K. Newman, and P. J. Newman
Endothelial cell PECAM-1 confers protection against endotoxic shock
Am J Physiol Heart Circ Physiol, January 1, 2005; 288(1): H159 - H164.
[Abstract] [Full Text] [PDF]

L. Cui, K. Johkura, F. Yue, N. Ogiwara, Y. Okouchi, K. Asanuma, and K. Sasaki
Spatial Distribution and Initial Changes of SSEA-1 and Other Cell Adhesion-related Molecules on Mouse Embryonic Stem Cells Before and During Differentiation
J. Histochem. Cytochem., November 1, 2004; 52(11): 1447 - 1457.
[Abstract] [Full Text] [PDF]

C. D. O'Brien, G. Cao, A. Makrigiannakis, and H. M. DeLisser
Role of immunoreceptor tyrosine-based inhibitory motifs of PECAM-1 in PECAM-1-dependent cell migration
Am J Physiol Cell Physiol, October 1, 2004; 287(4): C1103 - C1113.
[Abstract] [Full Text] [PDF]

C. Gao, W. Sun, M. Christofidou-Solomidou, M. Sawada, D. K. Newman, C. Bergom, S. M. Albelda, S. Matsuyama, and P. J. Newman
PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis
Blood, July 1, 2003; 102(1): 169 - 179.
[Abstract] [Full Text] [PDF]

L. Righi, S. Deaglio, C. Pecchioni, A. Gregorini, A. L. Horenstein, G. Bussolati, A. Sapino, and F. Malavasi
Role of CD31/Platelet Endothelial Cell Adhesion Molecule-1 Expression in in Vitro and in Vivo Growth and Differentiation of Human Breast Cancer Cells
Am. J. Pathol., April 1, 2003; 162(4): 1163 - 1174.
[Abstract] [Full Text] [PDF]

C. D. O'Brien, P. Lim, J. Sun, and S. M. Albelda
PECAM-1-dependent neutrophil transmigration is independent of monolayer PECAM-1 signaling or localization
Blood, April 1, 2003; 101(7): 2816 - 2825.
[Abstract] [Full Text] [PDF]

G. Ji, C. D. O'Brien, M. Feldman, Y. Manevich, P. Lim, J. Sun, S. M. Albelda, and M. I. Kotlikoff
PECAM-1 (CD31) regulates a hydrogen peroxide-activated nonselective cation channel in endothelial cells
J. Cell Biol., April 1, 2002; 157(1): 173 - 184.
[Abstract] [Full Text] [PDF]

T. Zhao and P. J. Newman
Integrin Activation by Regulated Dimerization and Oligomerization of Platelet Endothelial Cell Adhesion Molecule (PECAM)-1 from Within the Cell
J. Cell Biol., January 8, 2001; 152(1): 65 - 74.
[Abstract] [Full Text] [PDF]

E. Sans, E. Delachanal, and A. Duperray
Analysis of the Roles of ICAM-1 in Neutrophil Transmigration Using a Reconstituted Mammalian Cell Expression Model: Implication of ICAM-1 Cytoplasmic Domain and Rho-Dependent Signaling Pathway
J. Immunol., January 1, 2001; 166(1): 544 - 551.
[Abstract] [Full Text] [PDF]

N. Sheibani, C. M. Sorenson, and W. A. Frazier
Differential Modulation of Cadherin-mediated Cell-Cell Adhesion by Platelet Endothelial Cell Adhesion Molecule-1 Isoforms through Activation of Extracellular Regulated Kinases
Mol. Biol. Cell, August 1, 2000; 11(8): 2793 - 2802.
[Abstract] [Full Text]

F. Anfosso, N. Bardin, E. Vivier, F. Sabatier, J. Sampol, and F. Dignat-George
Outside-in Signaling Pathway Linked to CD146 Engagement in Human Endothelial Cells
J. Biol. Chem., January 5, 2001; 276(2): 1564 - 1569.
[Abstract] [Full Text] [PDF]

G. Ji, C. D. O'Brien, M. Feldman, Y. Manevich, P. Lim, J. Sun, S. M. Albelda, and M. I. Kotlikoff
PECAM-1 (CD31) regulates a hydrogen peroxide-activated nonselective cation channel in endothelial cells
J. Cell Biol., April 1, 2002; 157(1): 173 - 184.
[Abstract] [Full Text] [PDF]

G. Cao, C. D. O'Brien, Z. Zhou, S. M. Sanders, J. N. Greenbaum, A. Makrigiannakis, and H. M. DeLisser
Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migration
Am J Physiol Cell Physiol, May 1, 2002; 282(5): C1181 - C1190.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Sun, J.

Articles by Albelda, S. M.

Search for Related Content

PubMed

PubMed Citation

Articles by Sun, J.

Articles by Albelda, S. M.

				C. Garnacho, V. Shuvaev, A. Thomas, L. McKenna, J. Sun, M. Koval, S. Albelda, V. Muzykantov, and S. Muro RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1 Blood, March 15, 2008; 111(6): 3024 - 3033. [Abstract] [Full Text] [PDF]

				K. J. D. A. Excoffon, G. L. Traver, and J. Zabner The Role of the Extracellular Domain in the Biology of the Coxsackievirus and Adenovirus Receptor Am. J. Respir. Cell Mol. Biol., June 1, 2005; 32(6): 498 - 503. [Abstract] [Full Text] [PDF]

				P. L. W. Yun, A. A. Decarlo, C. C. Chapple, and N. Hunter Functional Implication of the Hydrolysis of Platelet Endothelial Cell Adhesion Molecule 1 (CD31) by Gingipains of Porphyromonas gingivalis for the Pathology of Periodontal Disease Infect. Immun., March 1, 2005; 73(3): 1386 - 1398. [Abstract] [Full Text] [PDF]

				M. Maas, M. Stapleton, C. Bergom, D. L. Mattson, D. K. Newman, and P. J. Newman Endothelial cell PECAM-1 confers protection against endotoxic shock Am J Physiol Heart Circ Physiol, January 1, 2005; 288(1): H159 - H164. [Abstract] [Full Text] [PDF]

				L. Cui, K. Johkura, F. Yue, N. Ogiwara, Y. Okouchi, K. Asanuma, and K. Sasaki Spatial Distribution and Initial Changes of SSEA-1 and Other Cell Adhesion-related Molecules on Mouse Embryonic Stem Cells Before and During Differentiation J. Histochem. Cytochem., November 1, 2004; 52(11): 1447 - 1457. [Abstract] [Full Text] [PDF]

				C. D. O'Brien, G. Cao, A. Makrigiannakis, and H. M. DeLisser Role of immunoreceptor tyrosine-based inhibitory motifs of PECAM-1 in PECAM-1-dependent cell migration Am J Physiol Cell Physiol, October 1, 2004; 287(4): C1103 - C1113. [Abstract] [Full Text] [PDF]

				C. Gao, W. Sun, M. Christofidou-Solomidou, M. Sawada, D. K. Newman, C. Bergom, S. M. Albelda, S. Matsuyama, and P. J. Newman PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis Blood, July 1, 2003; 102(1): 169 - 179. [Abstract] [Full Text] [PDF]

				L. Righi, S. Deaglio, C. Pecchioni, A. Gregorini, A. L. Horenstein, G. Bussolati, A. Sapino, and F. Malavasi Role of CD31/Platelet Endothelial Cell Adhesion Molecule-1 Expression in in Vitro and in Vivo Growth and Differentiation of Human Breast Cancer Cells Am. J. Pathol., April 1, 2003; 162(4): 1163 - 1174. [Abstract] [Full Text] [PDF]

				C. D. O'Brien, P. Lim, J. Sun, and S. M. Albelda PECAM-1-dependent neutrophil transmigration is independent of monolayer PECAM-1 signaling or localization Blood, April 1, 2003; 101(7): 2816 - 2825. [Abstract] [Full Text] [PDF]

				G. Ji, C. D. O'Brien, M. Feldman, Y. Manevich, P. Lim, J. Sun, S. M. Albelda, and M. I. Kotlikoff PECAM-1 (CD31) regulates a hydrogen peroxide-activated nonselective cation channel in endothelial cells J. Cell Biol., April 1, 2002; 157(1): 173 - 184. [Abstract] [Full Text] [PDF]

				T. Zhao and P. J. Newman Integrin Activation by Regulated Dimerization and Oligomerization of Platelet Endothelial Cell Adhesion Molecule (PECAM)-1 from Within the Cell J. Cell Biol., January 8, 2001; 152(1): 65 - 74. [Abstract] [Full Text] [PDF]

				E. Sans, E. Delachanal, and A. Duperray Analysis of the Roles of ICAM-1 in Neutrophil Transmigration Using a Reconstituted Mammalian Cell Expression Model: Implication of ICAM-1 Cytoplasmic Domain and Rho-Dependent Signaling Pathway J. Immunol., January 1, 2001; 166(1): 544 - 551. [Abstract] [Full Text] [PDF]

				N. Sheibani, C. M. Sorenson, and W. A. Frazier Differential Modulation of Cadherin-mediated Cell-Cell Adhesion by Platelet Endothelial Cell Adhesion Molecule-1 Isoforms through Activation of Extracellular Regulated Kinases Mol. Biol. Cell, August 1, 2000; 11(8): 2793 - 2802. [Abstract] [Full Text]

				F. Anfosso, N. Bardin, E. Vivier, F. Sabatier, J. Sampol, and F. Dignat-George Outside-in Signaling Pathway Linked to CD146 Engagement in Human Endothelial Cells J. Biol. Chem., January 5, 2001; 276(2): 1564 - 1569. [Abstract] [Full Text] [PDF]

				G. Cao, C. D. O'Brien, Z. Zhou, S. M. Sanders, J. N. Greenbaum, A. Makrigiannakis, and H. M. DeLisser Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migration Am J Physiol Cell Physiol, May 1, 2002; 282(5): C1181 - C1190. [Abstract] [Full Text] [PDF]