Avraham, K. B., Hasson, T., Steel, K. P., Kingsley, D. M., Russell, L. B., Mooseker, M. S., Copeland, N. G. and Jenkins, N. A (1995). The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nature Genet 11, 369-375.[Medline]
Bejsovec, A. and Anderson, P (1988). Myosin heavy-chain mutations that disrupt Caenorhabditis elegans thick filament assembly. Genes Dev 2, 1307-1317.[Abstract/Free Full Text]
Bejsovec, A. and Anderson, P (1990). Functions of the myosin ATP and actin binding sites are required for C. elegans thick filament assembly. Cell 60, 133-140.[Medline]
Bloom, G. S. and Endow, S. A (1995). Motor proteins 1: kinesins. Protein Profile 2, 1109-1171.
Bourne, H. R., Sanders, D. A. and McCormick, F (1991). The GTPase superfamily: conserved structure and molecular mechanism. Nature 349, 117-127.[Medline]
Brady, S. T (1985). A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317, 73-75.[Medline]
Brown, S. S (1999). Cooperation between microtubule-and actin-based motor proteins. Annu. Rev. Cell Dev. Biol 15, 63-80.[Medline]
Chalfie, M., Tu, Y., Euskirchen, G., Ward, W. W. and Prasher, D. C (1994). Green fluorescent protein as a marker for gene expression. Science 263, 802-805.[Abstract/Free Full Text]
Cooke, R (1986). The mechanism of muscle contraction. CRC Crit. Rev. Biochem 21, 53-118.[Medline]
Crevel, I. M.-T. C., Lockhart, A. and Cross, R. A (1996). Weak and strong states of kinesin and ncd. J. Mol. Biol 257, 66-76.[Medline]
Dominguez, R., Freyzon, Y., Trybus, K., M. and Cohen, C (1998). Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state. Cell 94, 559-571.[Medline]
Endow, S. A (1999). Microtubule motors in spindle and chromosome motility. Eur. J. Biochem 262, 12-18.[Medline]
Fisher, A. J., Smith, C. A., Thoden, J. B., Smith, R., Sutoh, K., Holden, H.M. and Rayment, I (1995). X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADPBeF x and MgADPAlF4. Biochemistry 34, 8960-8972.[Medline]
Franken, S. M., Scheidig, A. J., Krengel, U., Rensland, H., Lautwein, A., Geyer, M., Scheffzek, K., Goody, R. S., Kalbitzer, H. R., Pai, E. F. et al (1993). Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras. Biochemistry 32, 8411-8420.[Medline]
Frech, M., Darden, T. A., Pedersen, L. G., Foley, C. K., Charifson, P. S., Anderson, M. W. and Wittinghofer, A (1994). Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study. Biochemistry 33, 3237-3244.[Medline]
Funatsu, T., Harada, Y., Tokunaga, M., Saito, K. and Yanagida, T (1995). Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution. Nature 374, 555-559.[Medline]
Gibbons, I. R (1996). The role of dynein in microtubule-based motility. Cell Struct. Funct 21, 331-342.[Medline]
Gibson, F., Walsh, J., Mburu, P., Varela, A., Brown, K. A., Antonio, M., Beisel, K. W., Steel, K. P. and Brown, S. D (1995). A type VII myosin encoded by the mouse deafness gene shaker-1. Nature 374, 62-64.[Medline]
Greene, E. A., Henikoff, S. and Endow, S. A (1996). The kinesin home page. www. blocks. fhcrc. org/~kinesin/_Fb_Gulick, A. M., Song, H., Endow, S. A. and Rayment, I. (1998). X-ray crystal structure of the yeast Kar3 motor domain complexed with Mg\245ADP to 2. 3 \201 resolution. Biochemistry 37, 1769-1776.
Herskowitz, I (1987). Functional inactivation of genes by dominant negative mutations. Nature 329, 219-222.[Medline]
Hirokawa, N (1998). Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 279, 519-526.[Abstract/Free Full Text]
Hodge, T. P. and Cope, J (1996). The myosin home page. http://www. mrc-lmb. cam. ac. uk/myosin/myosin. html_Fb_Houdusse, A., Kalabokis, V. N., Himmel, D., Szent-Gyorgyi, A. G. and Cohen, C. (1999). Atomic structure of scallop myosin subfragment S1 complexed with MgADP: a novel conformation of the myosin head. Cell 14, 459-470.
Howard, J (1996). The movement of kinesin along microtubules. Annu. Rev. Physiol 58, 703-729.[Medline]
Hoyt, M. A., He, L., Totis, L. and Saunders, W. S (1993). Loss of function of Saccharomyces cerevisiae kinesin-related CIN8 and KIP1 is suppressed by KAR3 motor domain mutations. Genetics 135, 35-44.[Abstract]
Inoue, S. and Salmon, E. D (1995). Force generation by microtubule assembly/disassembly in mitosis and related movements. Mol. Biol. Cell 6, 1619-1640.[Medline]
Ishijima, A., Kojima, H., Funatsu, T., Tokunaga, M., Higuchi, H., Tanaka, H. and Yanagida, T (1998). Simultaneous observation of individual ATPase and mechanical events by a single myosin molecule during interaction with actin. Cell 92, 161-171.[Medline]
Kozielski, F., De Bonis, S., Burmeister, W. P., Cohen-Addad, C. and Wade, R. H (1999). The crystal structure of the minus-end-directed microtubule motor protein ncd reveals variable dimer conformations. Structure 7, 1407-1416.[Medline]
Kull, F. J., Sablin, E. P., Lau, R., Fletterick, R. J. and Vale, R. D (1996). Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature 380, 550-555.[Medline]
Ma, Y. Z. and Taylor, E. W (1995). Mechanism of microtubule kinesin ATPase. Biochemistry 34, 13242-13251.[Medline]
Muller, J., Marx, A., Sack, S., Song, Y. H. and Mandelkow, E (1999). The structure of the nucleotide-binding site of kinesin. Biol. Chem 380, 981-992.
Nasmyth, K. and Jansen, R. P (1997). The cytoskeleton in mRNA localization and cell differentiation. Curr. Opin. Cell Biol 9, 396-400.[Medline]
Nonaka, S., Tanaka, Y., Okada, Y., Takeda, S., Harada, A., Kanai, Y., Kido, M. and Hirokawa, N (1998). Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein. Cell 95, 829-837.[Medline]
Patterson, B. and Spudich, J. A (1995). A novel positive selection foridentifying cold-sensitive myosin II mutants in Dictyostelium. Genetics 140, 505-515.[Abstract]
Pechatnikova, E. and Taylor, E. W (1997). Kinetic mechanism of monomeric non-claret disjunctional protein (Ncd) ATPase. J. Biol. Chem 272, 30735-30740.[Abstract/Free Full Text]
Porter, J. A. and Montell, C (1993). Distinct roles of the Drosophila ninaC kinase and myosin domains revealed by systematic mutagenesis. J. Cell Biol 122, 601-612.[Abstract/Free Full Text]
Raw, A. S., Coleman, D. E., Gilman, A. G. and Sprang, S. R (1997). Structural and biochemical characterization of the GTPS-, GDP\245 Pi-, and GDP-bound forms of a GTPase-deficient Gly42 Val mutant of Gi1. Biochemistry 36, 15660-15669.[Medline]
Rayment, I., Rypniewski, W. R., Schmidt-Base, K., Smith, R., Tomchick, D. R., Benning, M. M., Winkelmann, D. A., Wesenberg, G. and Holden, H. M (1993). Three-dimensional structure of myosin subfragment-1: a molecular motor. Science 261, 50-58.[Abstract/Free Full Text]
Rosenfeld, S. S., Correia, J. J., Xing, J., Rener, B. and Cheung, H. C (1996). Structural studies of kinesin-nucleotide intermediates. J. Biol. Chem 271, 30-.
Ruppel, K. M. and Spudich, J. A (1995). Myosin motor function: structural and mutagenic approaches. Curr. Opin. Cell Biol 7, 89-93.[Medline]
Ruppel, K. M. and Spudich, J. A (1996). Structure-function studies of the myosin motor domain: importance of the 50-kDa cleft. Mol. Biol. Cell 7, 1123-1136.[Abstract]
Sablin, E. P., Kull, F. J., Cooke, R., Vale, R. D. and Fletterick, R. J (1996). Crystal structure of the motor domain of the kinesin-related motor ncd. Nature 380, 555-559.[Medline]
Sack, S., Kull, F. J. and Mandelkow, E (1999). Motor proteins of the kinesin family Structure, variations and nucleotide binding sites. Eur. J. Biochem 262, 1-11.[Medline]
Sasaki, N. and Sutoh, K (1998). Structure-mutation analysis of the ATPase site of Dictyostelium discoideum myosin II. Adv. Biophys 35, 1-24.[Medline]
Saunders, W. S. and Hoyt, M. A (1992). Kinesin-related proteins required for structural integrity of the mitotic spindle. Cell 70, 451-458.[Medline]
Saxton, W. M., Hicks, J., Goldstein, L. S. B. and Raff, E. C (1991). Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosis. Cell 64, 1093-1102.[Medline]
Scott, W. G., Murray, J. B., Arnold, J. R. P., Stoddard, B. L. and Klug, A (1996). Capturing the structure of a catalytic RNA intermediate: the hammerhead ribozyme. Science 274, 2065-2069.[Abstract/Free Full Text]
Sellers, J. R. and Goodson, H. V (1995). Motor proteins 2: myosin. Protein Profile 2, 1323-1423.[Medline]
Shimada, T., Sasaki, N., Ohkura, R. and Sutoh, K (1997). Alanine scanning mutagenesis of the switch I region in the ATPase site of Dictyostelium discoideum myosin II. Biochemistry 36, 14037-14043.[Medline]
Song, H. and Endow, S. A (1998). Decoupling of nucleotide-and microtubule-binding in a kinesin mutant. Nature 396, 587-590.[Medline]
Sprang, S. R (1997). G protein mechanisms: insights from structural analysis. Annu. Rev. Biochem 66, 639-678.[Medline]
Stoddard, B. L., Cohen, B., E., Brubaker, M., Mesecar, A. D. and Koshland, D. E. J (1998). Millisecond Laue structures of an enzyme-product complex using photocaged substrate analogs. Nature Struct. Biol 5, 891-897.[Medline]
Suzuki, Y., Yasunaga, T., Ohkura, R., Wakabayashi, T. and Sutoh, K (1998). Swing of the lever arm of a myosin motor at the isomerization and phosphate-release steps. Nature 396, 380-383.[Medline]
Sweeney, H. L., Rosenfeld, S. S., Brown, F., Faust, L., Smith, J., Xing, J., Stein, L. and Sellers, J (1998). Kinetic tuning of myosin via a flexible loop adjacent to the nucleotide binding pocket. J. Biol. Chem 273, 6262-6270.[Abstract/Free Full Text]
Waters, J. C. and Salmon, E. D (1996). Cytoskeleton: a catastrophic kinesin. Curr. Biol 6, 361-363.[Medline]
Weil, D., Blanchard, S., Kaplan, J., Guilford, P., Gibson, F., Walsh, J., Mburu, P., Varela, A., Levilliers, J., Weston, M. D. et al (1995). Defective myosin VIIA gene responsible for Usher syndrome type 1B. Nature 374, 60-61.[Medline]
Wells, A. L., Lin, A. W., Chen, L.-Q., Safer, D., Cain, S. M., Hasson, T., Carragher, B. O., Milligan, R. A. and Sweeney, H. L (1999). Myosin VI is an actin-based motor that moves backwards. Nature 400, 505-508.
Woehlke, G., Ruby, A. K., Hart, C. L., Ly, B., Hom-Booher, N. and Vale, R. D (1997). Microtubule interaction site of the kinesin motor. Cell 90, 207-216.[Medline]
