Unique properties of lamp2a compared to other lamp2 isoforms

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Agarraberes, F., Terlecky, S. R. and Dice, J. F (1997). An intralysosomal hsp70 is required for a selective pathway of lysosomal protein degradation. J. Cell Biol 137, 825-834.[Abstract/Free Full Text]

Akasaki, K., Fukuzawa, H., Kinoshita, H., Furuno, K. and Tsuji, H (1993). Cycling of two endogenous lysosomal membrane proteins, lamp-2 and acid phosphatase, between the cell surface and lysosomes in cultured rat hepatocytes. J. Biochem 114, 598-604.

Akasaki, K. and Tsuji, H (1998). Purification and characterization of a soluble form of lysosome-associated membrane glycoprotein-2 (lamp-2) from rat liver lysosomal contents. Biochem. Mol. Biol. Int 46, 197-206.[Medline]

Andrejewski, N., Punnonen, E. L., Guhde, G., Tanaka, Y., Lullmann-Rauch, R., Hartmann, D., von Figura, K. and Saftig, P (1999). Normal lysosomal morphology and function in LAMP-1-deficient mice. J. Biol. Chem 274, 12692-12701.[Abstract/Free Full Text]

Aniento, F., Roche, E., Cuervo, A. M. and Knecht, E (1993). Uptake and degradation of glyceraldehyde-3-phosphate dehydrogenase by rat liver lysosomes. J. Biol. Chem 268, 10463-10470.[Abstract/Free Full Text]

Auteri, J. S., Okada, A., Bochaki, V. and Dice, J. F (1983). Regulation of intracellular protein degradation in IMR-90 human diploid fibroblasts. J. Cell. Physiol 115, 159-166.[Medline]

Carlsson, S. R., Roth, J., Piller, F. and Fukuda, M (1988). Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. J. Biol. Chem 263, 18911-18919.[Abstract/Free Full Text]

Chiang, H. L. and Dice, J. F (1988). Peptide sequences that target proteins for enhanced degradation during serum withdrawal. J. Biol. Chem 262, 6797-6805.

Chiang, H. L., Terlecky, S. R., Plant, C. P. and Dice, J. F (1989). A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins. Science 246, 382-385.[Abstract/Free Full Text]

Cuervo, A. M., Terlecky, S. R., Dice, J. F. and Knecht, E (1994). Selective binding and uptake of ribonuclease A and glyceraldehyde-3-phosphate dehydrogenase by rat liver lysosomes. J. Biol. Chem 269, 26374-26380.[Abstract/Free Full Text]

Cuervo, A. M., Knecht, E., Terlecky, S. R. and Dice, J. F (1995). Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation. Am. J. Physiol 269, 1200-.

Cuervo, A. M. and Dice, J. F (1996). A receptor for the selective uptake and degradation of proteins by lysosomes. Science 273, 501-503.[Abstract]

Cuervo, A. M., Dice, J. F. and Knecht, E (1997). A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins. J. Biol. Chem 272, 5606-5615.[Abstract/Free Full Text]

Cuervo, A. M., Hildebrand, H., Bomhard, E. M. and Dice, J. F (1999). Direct lysosomal uptake of alpha2-microglobulin contributes to chemically induced nephropathy. Kidney Int 55, 529-545.[Medline]

Cuervo, A. M. and Dice, J. F (1998). Lysosomes, a meeting point of proteins, chaperones, and proteases. J. Mol. Med 76, 6-12.[Medline]

Cuervo, A. M. and Dice, J. F (2000). Age-related decline in chaperone-mediated autophagy. J. Biol. Chem 275, 31505-31513.[Abstract/Free Full Text]

Dice, J. F., Chiang, H.-L., Spencer, E. P. and Backer, J. M (1986). Regulation of catabolism of microinjected ribonuclease A: Identification of residues 7-11 as the essential pentapeptide. J. Biol. Chem 262, 6853-6859.

Dice, J. F (1990). Peptide sequences that target cytosolic proteins for lysosomal proteolysis. Trends Biochem. Sci 15, 305-309.[Medline]

Dice, J. F (1993). Cellular and molecular mechanisms of aging. Physiol. Rev 73, 149-159.[Free Full Text]

Fukuda, M (1991). Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking. J. Biol. Chem 266, 21327-21330.[Free Full Text]

Furuno, K., Yano, S., Akasaki, K., Tanaka, Y., Yamaguchi, Y., Tsuji, H., Himeno, M. and Kato, K (1989). Biochemical analysis of the movement of a major lysosomal membrane glycoprotein in the endocytic membrane system. J. Biochem 106, 717-722.

Furuta, K., Yang, X. L., Chen, J. S., Hamilton, S. R. and August, J. T (1999). Differential expression of the lysosome-associated membrane proteins in normal human tissues. Arch. Biochem. Biophys 365, 75-82.[Medline]

Gottschalk, S., Waheed, A., Schmidt, B., Laidler, P. and von Figura, K (1989). Sequential processing of lysosomal acid phosphatase by a cytoplasmic thiol proteinase and a lysosomal aspartyl proteinase. EMBO J 8, 3215-3219.[Medline]

Gough, N. R., Hatem, C. L. and Fambrough, D. M (1995). The family of LAMP-2 proteins arises by alternative splicing from a single gene: characterization of the avian LAMP-2 gene and identification of mammalian homologs of LAMP-2b and LAMP-2c. DNA Cell Biol 14, 863-867.[Medline]

Gough, N. R. and Fambrough, D. M (1997). Different steady state subcellular distribution of the three splice variants of lysosome-associated membrane protein LAMP-2 are determined largely by the COOH-terminal amino acid residue. J. Cell Biol 137, 1161-116779.[Abstract/Free Full Text]

Guarnieri, F. G., Arterburn, L. M., Penno, M. B., Cha, Y. and August, J. T (1993). The motif tyr-X-X-hydrophobic residue mediates lysosomal membrane targeting of lysosome-associated membrane protein 1. J. Biol. Chem 268, 1941-1946.[Abstract/Free Full Text]

Hatem, C. L., Gough, N. R. and Fambrough, D. M (1995). Multiple mRNAs encode the avian lysosomal membrane protein LAMP-2 resulting in alternative transmembrane and cytoplasmic domains. J. Cell Sci 108, 2093-2100.[Abstract]

Jadot, M., Wattiaux, R., Mainferme, F., Dubois, F., Claessens, A. and Wattiaux-De Coninck, S (1996). Soluble form of Lamp II in purified rat liver lysosomes. Biochem. Biophys. Res. Commun 223, 353-359.[Medline]

Jadot, M., Dubois, F., Wattiaux-DeConinck, S. and Wattiaux, R (1997). Supramolecular assemblies from lysosomal matrix proteins and complex lipids. Eur. J. Biochem 249, 862-869.[Medline]

Jentoft, N. and Dearborn, D. G (1983). Protein labeling by reductive alkylation. Meth. Enzymol 91, 570-579.[Medline]

Konecki, D. S., Foetisch, K., Zimmer, K. P., Schlotter, M. and Lichter-Konecki, U (1995). An alternatively spliced form of the human lysosome-associated membrane protein-2 gene is expressed in a tissue-specific manner. Biochem. Biophys. Res. Commun 215, 757-767.[Medline]

Laemmli, U (1970). Cleavage of structural proteins during the assembly of the head of the bacteriophage T4. Nature 227, 680-685.[Medline]

Licheter-Konecki, U., Moter, S. E., Krawisz, B. R., Schlotter, M., Hipke, C. and Konecki, D. S (1999). Expression patterns of murine lysosome-associated membrane protein 2 (Lamp-2) transcripts during morphogenesis. Differentiation 65, 43-58.[Medline]

Lippincott-Schwartz, J. and Fambrough, D. M (1986). Lysosomal membrane dynamics: structure and interorganellar movement of a major lysosomal membrane glycoprotein. J. Cell Biol 102, 1593-1605.[Abstract/Free Full Text]

Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Randall, R. J (1951). Protein measurement with the Folin phenol reagent. J. Biol. Chem 193, 265-275.[Free Full Text]

Nishiyama, K., Fukuda, A., Morita, K. and Tokuda, H (1999). Membrane deinsertion of SecA underlying proton motive force-dependent stimulation of protein translocation. EMBO J 18, 1049-1058.[Medline]

Ohsumi, Y., Ishikawa, T. and Kato, K (1983). A rapid and simplified method for the preparation of lysosomal membranes from rat liver. J. Biochem 93, 547-556.

Peters, C. and von Figura, K (1994). Biogenesis of lysosomal membranes. FEBS Lett 346, 108-114.[Medline]

Ravetch, J. V. and Perussia, B (1989). Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions. J. Exp. Med 170, 481-497.[Abstract/Free Full Text]

Saitoh, O., Wang, W. C., Lotan, R. and Fukuda, M (1992). Differential glycosylation and cells surface expression of lysosomal membrane glycoproteins in sublines of a human colon cancer exhibiting distinct metastatic potentials. J. Biol. Chem 267, 5700-5711.[Abstract/Free Full Text]

Storrie, B. and Madden, E. A (1990). Isolation of subcellular organelles. Meth. Enzymol 182, 203-225.[Medline]

Tanaka, Y., et al. ( (2000). Accumulation of autophagic vacuoles and cardiomyopathy in Lamp-2-deficient mice. Nature 406, 902-906.[Medline]

Terlecky, S. R. and Dice, J. F (1993). Polypeptide import and degradation by isolated lysosomes. J. Biol. Chem 268, 23490-23495.[Abstract/Free Full Text]

Towbin, H., Staehelin, T. and Gordon, J (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedures and some applications. Proc. Nat. Acad. Sci. USA 76, 4350-4353.[Abstract/Free Full Text]

Wattiaux, R., Wattiaux-De Coninck, S., Ronveaux-Dupal, M. F. and Dubois, F (1978). Isolation of rat liver lysosomes by isopycnic centrifugation in a metrizamide gradient. J. Cell Biol 78, 349-368.[Abstract/Free Full Text]

Welch, W. J. and Feramisco, J. R (1985). Rapid purification of mammalian 70,000-dalton stress proteins: affinity of the proteins for nucleotides. Mol. Cell Biol 5, 1229-1237.[Abstract/Free Full Text]

Williams, M. A. and Fukuda, M (1990). Accumulation of membrane glycoproteins in lysosomes requires a tyrosine residue at a particular position in the cytoplasmic tail. J. Cell Biol 111, 955-966.[Abstract/Free Full Text]

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