Anderson, J. M., Stevenson, B. R., Jesaitis, L. A., Goodenough, D. A. and Mooseker, M. S (1988). Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells. J. Cell Biol 106, 1141-1149.[Abstract/Free Full Text]
Anderson, J. M. and Van Itallie, C. M (1995). Tight junctions and the molecular basis for regulation of paracellular permeability. Am. J. Physiol 269, 467-.
Ando-Akatsuka, Y., Saitou, M., Hirase, T., Kishi, M., Sakakibara, A., Itoh, M., Yonemura, S., Furuse, M. and Tsukita, S (1996). Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog and rat-kangaroo homologues. J. Cell Biol 133, 43-47.[Abstract/Free Full Text]
Balda, M. S., Whitney, J. A., Flores, C., Gonzalez, S., Cereijido, M. and Matter, K (1996). Functional dissociation of paracellular permeability from electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant membrane protein of tight junctions. J. Cell Biol 134, 1031-1049.[Abstract/Free Full Text]
Bamforth, S. D., Kniesel, U., Wolburg, H., Engelhardt, B. and Risau, W (1999). A dominant mutant of occludin disrupts tight junction structure and function. J. Cell Sci 112, 1879-1888.[Abstract]
Barth, A. I., Pollack, A. L., Altschuler, Y., Mostov, K. E. and Nelson, W. J (1997). NH2-terminal deletion of-catenin results in stable colocalization of mutant -catenin with adenomatous polyposis coli protein and altered MDCK adhesion. J. Cell Biol 136, 693-706.[Abstract/Free Full Text]
Chen, Y.-H., Merzdorf, C., Paul, D. L. and Goodenough, D. A (1997). COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J. Cell Biol 138, 891-899.[Abstract/Free Full Text]
Citi, S., Sabanay, H., Jakes, R., Geiger, B. and Kendrick-Jones, J (1988). Cingulin, a new peripheral component of tight junctions. Nature 333, 272-276.[Medline]
Claude, P. and Goodenough, D. A (1973). Fracture faces of zonulae occludentes from \324tight' and \324leaky' epithelia. J. Cell Biol 58, 390-400.[Abstract/Free Full Text]
Claude, P (1978). Morphological factors influencing transepithelial permeability: A model for the resistance of the zonula occludens. J. Membr. Biol 39, 219-232.[Medline]
Dragsten, P. R., Blumenthal, R. and Handler, J. S (1981). Membrane asymmetry in epithelia: is the tight junction a barrier to diffusion in the plasma membrane?. Nature 294, 718-722.[Medline]
Evan, G. I., Lewis, G. K., Ramsay, G. and Bishop, M. J (1985). Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product. Mol. Cell. Biol 5, 3610-3616.[Abstract/Free Full Text]
Fallon, R. F. and Goodenough, D. A (1981). Five hour half-life of mouse liver gap-junction protein. J. Cell Biol 90, 521-526.[Abstract/Free Full Text]
Fanning, A. S., Jameson, B. J., Jesaitis, L. A. and Anderson, J. M (1998). The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J. Biol. Chem 273, 29745-29753.[Abstract/Free Full Text]
Farquhar, M. G. and Palade, G. E (1963). Junctional complexes in various epithelia. J. Cell Biol 17, 375-412.[Abstract/Free Full Text]
Fujimoto, K (1995). Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. J. Cell Sci 108, 3443-3449.[Abstract]
Furuse, M., Hirase, T., Itoh, M., Nagafuchi, A., Yonemura, S., Tsukita, S. and Tsukita, S (1993). Occludin: A novel integral membrane protein localizing at tight junctions. J. Cell Biol 123, 1777-1788.[Abstract/Free Full Text]
Furuse, M., Itoh, M., Hirase, T., Nagafuchi, A., Yonemura, S., Tsukita, S. and Tsukita, S (1994). Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J. Cell Biol 127, 1617-1626.[Abstract/Free Full Text]
Furuse, M., Fujimoto, K., Sato, N., Hirase, T., Tsukita, S. and Tsuktal, S (1996). Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracelular multilamellar bodies bearing tight junction-like structures. J. Cell Sci 109, 429-435.[Abstract]
Furuse, M., Fujita, K., Fujimoto, K. and Tsukita, S (1998). Claudin 1 and 2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J. Cell Biol 141, 1539-1550.[Abstract/Free Full Text]
Furuse, M., Sasaki, H., Fujimoto, K. and Tsukita, S (1998). A single gene product, claudin-1 or2, reconstitutes tight junction strands and recruits occludin in fibroblasts. J. Cell Biol 143, 391-401.[Abstract/Free Full Text]
Furuse, M., Sasaki, H. and Tsukita, S (1999). Manner of interaction of heterogeneous claudin species within and between tight junction strands. J. Cell Biol 147, 891-903.[Abstract/Free Full Text]
Gossen, M. and Bujard, H (1992). Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Nat. Acad. Sci. USA 89, 5547-5551.[Abstract/Free Full Text]
Gumbiner, B (1987). Structure and biochemistry and assembly of epithelial tight junctions. Am. J. Physiol 253, 749-.
Gumbiner, B., Lowenkopf, T. and Apatira, D (1991). Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc. Nat. Acad. Sci. USA 88, 3460-3464.[Abstract/Free Full Text]
Hasegawa, H., Fujita, H., Katoh, H., Aoki, J., Nakamura, K., Ichikawa, A. and Negishi, M (1999). Opposite regulation of transepithelial electrical resistance and paracellular permeability by Rho in Madin-Darby canine kidney cells. J. Biol. Chem 274, 20982-20988.[Abstract/Free Full Text]
Haskins, J., Lijie, G., Wittchen, E. S., Hibbard, J. and Stevenson, B. R (1998). ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J. Cell Biol 141, 199-208.[Abstract/Free Full Text]
Inai, T., J., K. and Shibata, Y (1999). Claudin-1 contributes tot he epithelial barrier function in MDCK cells. Eur. J. Cell Biol 78, 849-855.[Medline]
Itoh, M., Furuse, M., Morita, K., Kubota, K., Saitou, M. and Tsukita, S (1999). Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2 and ZO-3, with the COOH termini of claudins. J. Cell Biol 147, 1351-1363.[Abstract/Free Full Text]
Jesaitis, L. A. and Goodenough, D. A (1994). Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. J. Cell Biol 124, 949-961.[Abstract/Free Full Text]
Keon, B. H., Schafer, S., Kuhn, C., Grund, C. and Francke W. W (1996). Symplekin, a novel type of tight junction plaue protein. J. Cell Biol 134, 1003-1018.[Abstract/Free Full Text]
Kreis, T. E (1986). Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface. EMBO J 5, 931-941.[Medline]
Laemmli, U. K (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.[Medline]
Madara, J. L (1998). Regulation of the movement of solutes across tight junctions. Annu. Rev. Physiol 60, 143-159.[Medline]
McCarthy, K. M., Skare, I. B., Stankewich, M. C., Furuse, M., Tsukita, S., Rogers, R. A., Lynch, R. D. and Schneeberger, E. E (1996). Occludin is a functional component of the tight junction. J. Cell Sci 109, 2287-2298.[Abstract]
Mitic, L. L., Schneeberger, E. E., Fanning, A. S. and Anderson, J. M (1999). Connexin-occludin chimeras containing the ZO-binding domain of occludin localize at MDCK tight junctions and NRK cell contacts. J. Cell Biol 146, 683-693.[Abstract/Free Full Text]
Mollgard, K., Malinowski, D. N. and Saunders, N. R (1976). Lack ofcorrelation between tight junction morphology and permeability properties in developing choroid plexus. Nature 264, 293-294.[Medline]
Morita, K., Furuse, M., Fujimoto, K. and Tsukita, S (1999). Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Nat. Acad. Sci. USA 96, 511-516.[Abstract/Free Full Text]
Morita, K., Sasake, H., Furuse, M. and Tsukita, S (1999). Endothdlial claudin: Claudin-5/TMVCF constitiutes tight junction strands in endothelial cells. J. Cell Biol 147, 185-194.[Abstract/Free Full Text]
Morita, K., Sasaki, H., Fujimoto, K., Furuse, M. and Tsukita, S (1999). Claudin-11/OSP-based tight junctions of myelin sheaths in brain and Sertoli cells in testis. J. Cell Biol 145, 579-588.[Abstract/Free Full Text]
Rochat, T., Casale, J., Hunninghake, G. W. and Peterson, M. W (1988). Neutrophil cathepsin G increases permeability of cultured type II pneumocytes. Am. J. Physiol 255, 603-.
Rodriguez-Boulan, E. and Nelson, W. J (1989). Morphogenesis of the polarized epithelial cell phenotype. Science 245, 718-725.[Abstract/Free Full Text]
Saitou, M., Fujimoto, K., Doi, Y., Itoh, M., Fujimoto, T., Furuse, M., Takano, H., Noda, T. and Tsukita, S (1998). Occludin-deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J. Cell Biol 141, 397-408.[Abstract/Free Full Text]
Schneeberger, E. E. and Lynch, R. D (1992). Structure, function and regulation of cellular tight junctions. Am. J. Physiol 262, 647-.
Simon, D. B., Lu, Y., Choate, K. A., Velazquez, H., Al-Sabban, E., Praga, M., Casari, G., Bettinelli, A., Colussi, G., Rodriguez-Soriano, J. et al. ( (1999). Paracellin-1, a renal tight junction protein required for paracellular Mg2+resorption. Science 285, 103-106.[Abstract/Free Full Text]
Sonoda, N., Furuse, M., Sasaki, H., Yonemura, S., Katahira, J.,Horiguchi, Y. and Tsukta, S (1999). Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier. J. Cell Biol 147, 195-204.[Abstract/Free Full Text]
Stevenson, B. R., Siliciano, J. D., Mooseker, J. D. and Goodenough, D. A (1986). Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol 103, 755-766.[Abstract/Free Full Text]
Stevenson, B. R., Anderson, J. M., Goodenough, D. A. and Mooseker, M. S (1988). Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial electrical resistance. J. Cell Biol 107, 2401-2408.[Abstract/Free Full Text]
Towbin, H., Staehelin, T. and Gordon, J (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Nat. Acad. Sci. USA 76, 4350-4354.[Abstract/Free Full Text]
Van Meer, G. and Simons, K (1986). The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells. EMBO J 5, 1455-1464.[Medline]
Van Meer, G., Gumbiner, G. and Simons, K (1986). The tight junction does not allow lipid molecules to diffuse from one epithelial cell to the next. Nature 322, 639-641.[Medline]
Wittchen, E. S., Haskins, J. and Stevenson, B. R (1999). Protein interactions at the tight junction. J. Biol. Chem 274, 35179-35185.[Abstract/Free Full Text]
Zhong, Y., Saitoh, T., Minase, T., Sawada, N., Enomoto, K. and Mori, M (1993). Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2. J. Cell Biol 120, 477-483.[Abstract/Free Full Text]