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Akita, M., Sasaki, S., Matsuyama, S. and Mizushima, S (1990). SecA interacts with secretory proteins by recognizing the positive charge at the amino terminus of the signal peptide in Escherichia coli. J. Biol. Chem 265, 8164-8169.[Abstract/Free Full Text]

Beltzer, J. P., Fiedler, K., Fuhrer, C., Geffen, I., Handschin, C., Wessels, H. P. and Spiess, M (1991). Charged residues are major determinants of the transmembrane orientation of a signal-anchor sequence. J. Biol. Chem 266, 973-978.[Abstract/Free Full Text]

Bibi, E. and Beja, O (1994). Membrane topology of multidrug resistance protein expressed in Escherichia coli . N-terminal domain. J. Biol. Chem 269, 19910-19915.[Abstract/Free Full Text]

Blobel, G (1980). Intracellular protein topogenesis. Proc. Natl. Acad. Sci. USA 77, 1496-1500.[Abstract/Free Full Text]

Borel, A. C. and Simon, S. M (1996). Biogenesis of polytopic membraneproteins: membrane segments assemble within translocation channels prior to membrane integration. Cell 85, 379-389.[Medline]

Chen, M. and Zhang, J. T (1996). Membrane insertion, processing, and topology of cystic fibrosis transmembrane conductance regulator (CFTR) in microsomal membranes. Mol. Membr. Biol 13, 33-40.[Medline]

Cianfriglia, M., Poloni, F., Signoretti, C., Romagnoli, G., Tombesi, M. and Felici, F (1996). Topology of MDR1-P-glycoprotein as indicated by epitope mapping of monoclonal antibodies to human MDR cells. Cytotechnology 19, 247-251.[Medline]

Doige, C. A. and Ames, G. F (1993). ATP-dependent transport systems in bacteria and humans: relevance to cystic fibrosis and multidrug resistance. Annu. Rev. Microbiol 47, 291-319.[Medline]

Gottesman, M. M., Hrycyna, C. A., Schoenlein, P. V., Germann, U. A. and Pastan, I (1995). Genetic analysis of the multidrug transporter. Annu. Rev. Genet 29, 607-649.[Medline]

Gottesman, M. M. and Pastan, I (1993). Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem 62, 385-427.[Medline]

Han, E. S. and Zhang, J. T (1998). Mechanism involved in generating the carboxyl-terminal half topology of P-glycoprotein. Biochemistry 37, 11996-12004.[Medline]

Hartmann, E., Rapoport, T. A. and Lodish, H. F (1989). Predicting the orientation of eukaryotic membrane-spanning proteins. Proc. Natl. Acad. Sci. USA 86, 5786-5790.[Abstract/Free Full Text]

Hegde, R. S. and Lingappa, V. R (1996). Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol. Cell 85, 217-228.[Medline]

Hegde, R. S., Mastrianni, J. A., Scott, M. R., DeFea, K. A., Tremblay, P., Torchia, M., DeArmond, S. J., Prusiner, S. B. and Lingappa, V. R (1998). A transmembrane form of the prion protein in neurodegenerative disease. Science 279, 827-834.[Abstract/Free Full Text]

Hegde, R. S., Voigt, S., Rapoport, T. A. and Lingappa, V. R (1998). TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum. Cell 92, 621-631.[Medline]

Higgins, C. F (1992). ABC transporters: from microorganisms to man. Annu. Rev. Cell Biol 8, 67-113.

Kast, C., Canfield, V., Levenson, R. and Gros, P (1995). Membrane topology of P-glycoprotein as determined by epitope insertion: transmembrane organization of the N-terminal domain of mdr3. Biochemistry 34, 4402-4411.[Medline]

Liao, S., Lin, J., Do, H. and Johnson, A. E (1997). Both lumenal and cytosolic gating of the aqueous ER translocon pore are regulated from inside the ribosome during membrane protein integration [see comments]. Cell 90, 31-41.[Medline]

Ling, V (1997). Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemo. Pharmacol 40, 3-8.

Lipp, J., Flint, N., Haeuptle, M. T. and Dobberstein, B (1989). Structural requirements for membrane assembly of proteins spanning the membrane several times. J. Cell Biol 109, 2013-2022.[Abstract/Free Full Text]

Loo, T. W. and Clarke, D. M (1995). Membrane topology of a cysteine-less mutant of human P-glycoprotein. J. Biol. Chem 270, 843-848.[Abstract/Free Full Text]

Lopez, C. D., Yost, C. S., Prusiner, S. B., Myers, R. M. and Lingappa, V. R (1990). Unusual topogenic sequence directs prion protein biogenesis. Science 248, 226-229.[Abstract/Free Full Text]

Montesano, L. and Glitz, D. G (1988). Wheat germ cytoplasmic ribosomes. Structure of ribosomal subunits and localization of N6,N6-dimethyladenosine by immunoelectron microscopy. J. Biol. Chem 263, 4932-4938.[Abstract/Free Full Text]

Mothes, W., Heinrich, S. U., Graf, R., Nilsson, I., von Heijne, G., Brunner, J. and Rapoport, T. A (1997). Molecular mechanism of membrane protein integration into the endoplasmic reticulum. Cell 89, 523-533.[Medline]

Parks, G. D. and Lamb, R. A (1991). Topology of eukaryotic type II membrane proteins: importance of N-terminal positively charged residues flanking the hydrophobic domain. Cell 64, 777-787.[Medline]

Poloni, F., Romagnoli, G., Cianfriglia, M. and Felici, F (1995). Isolation of antigenic mimics of MDR1-P-glycoprotein by phage-displayed peptide libraries. Int. J. Cancer 61, 727-731.[Medline]

Romagnoli, G., Poloni, F., Flego, M., Moretti, F., Di Modugno, F., Chersi, A., Falasca, G., Signoretti, C., Castagna, M. and Cianfriglia, M (1999). Epitope mapping of the monoclonal antibody MM12.10 to external MDR1 P-glycoprotein domain by synthetic peptide scanning and phage display technologies. Biol. Chem 380, 553-559.

Sipos, L. and von Heijne, G (1993). Predicting the topology of eukaryotic membrane proteins. Eur. J. Biochem 213, 1333-1340.[Medline]

Skach, W. R., Calayag, M. C. and Lingappa, V. R (1993). Evidence for an alternate model of human P-glycoprotein structure and biogenesis. J. Biol. Chem 268, 6903-6908.[Abstract/Free Full Text]

Slatin, S. L., Qiu, X.-Q., Jakes, K. S. and Finkelstein, A (1994). Identification of a translocated protein segment in a voltage-dependent channel. Nature 371, 158-161.[Medline]

Spiess, M., Handschin, C. and Baker, K. P (1989). Stop-transfer activity of hydrophobic sequences depends on the translation system. J. Biol. Chem 264, 19117-19124.[Abstract/Free Full Text]

Spremulli, L. L., Walthall, B. J., Lax, S. R. and Ravel, J. M (1977). Purification and properties of a Met-tRNAf binding factor from wheat germ. Arch. Biochem. Biophys 178, 565-575.[Medline]

Treadwell, B. V., Mauser, L. and Robinson, W. G (1979). Initiation factors for protein synthesis from wheat germ. Methods Enzymol 60, 181-193.[Medline]

Walter, P. and Blobel, G (1983). Preparation of microsomal membranes for cotranslational protein translocation. Methods Enzymol 96, 84-93.[Medline]

Wang, C., Chen, M., Han, E. and Zhang, J. T (1997). Role of ribosomes in reinitiation of membrane insertion of internal transmembrane segments in a polytopic membrane protein. Biochemistry 36, 11437-11443.[Medline]

Wessels, H. P. and Spiess, M (1988). Insertion of a multispanning membraneprotein occurs sequentially and requires only one signal sequence. Cell 55, 61-70.[Medline]

Yost, C. S., Lopez, C. D., Prusiner, S. B., Myers, R. M. and Lingappa, V. R (1990). Non-hydrophobic extracytoplasmic determinant of stop transfer in the prion protein. Nature 343, 669-672.[Medline]

Zhang, J. T (1996). Sequence requirements for membrane assembly of polytopic membrane proteins: molecular dissection of the membrane insertion process and topogenesis of the human MDR3 P-glycoprotein. Mol. Biol. Cell 7, 1709-1721.[Abstract]

Zhang, J. T., Chen, M., Han, E. and Wang, C (1998). Dissection of de novo membrane insertion activities of internal transmembrane segments of ATP-binding-cassette transporters: toward understanding topological rules for membrane assembly of polytopic membrane proteins. Mol. Biol. Cell 9, 853-863.[Abstract/Free Full Text]

Zhang, J. T., Duthie, M. and Ling, V (1993). Membrane topology of the N-terminal half of the hamster P-glycoprotein molecule. J. Biol. Chem 268, 15101-15110.[Abstract/Free Full Text]

Zhang, J. T., Lee, C. H., Duthie, M. and Ling, V (1995). Topological determinants of internal transmembrane segments in P-glycoprotein sequences. J. Biol. Chem 270, 1742-1746.[Abstract/Free Full Text]

Zhang, J. T. and Ling, V (1991). Study of membrane orientation and glycosylated extracellular loops of mouse P-glycoprotein by in vitro translation. J. Biol. Chem 266, 18224-18232.[Abstract/Free Full Text]

Zhang, J. T. and Ling, V (1995). Involvement of cytoplasmic factors regulating the membrane orientation of P-glycoprotein sequences. Biochemistry 34, 9159-9165.[Medline]


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