Cdc7p-Dbf4p becomes famous in the cell cycle

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[Abstract] [Full Text] [PDF]

R. Bermejo, N. Vilaboa, and C. Cales
Regulation of CDC6, Geminin, and CDT1 in Human Cells that Undergo Polyploidization
Mol. Biol. Cell, November 1, 2002; 13(11): 3989 - 4000.
[Abstract] [Full Text] [PDF]

D. M. Chou, P. Petersen, J. C. Walter, and G. Walter
Protein Phosphatase 2A Regulates Binding of Cdc45 to the Prereplication Complex
J. Biol. Chem., October 18, 2002; 277(43): 40520 - 40527.
[Abstract] [Full Text] [PDF]

M. C. Edwards, A. V. Tutter, C. Cvetic, C. H. Gilbert, T. A. Prokhorova, and J. C. Walter
MCM2-7 Complexes Bind Chromatin in a Distributed Pattern Surrounding the Origin Recognition Complex in Xenopus Egg Extracts
J. Biol. Chem., August 30, 2002; 277(36): 33049 - 33057.
[Abstract] [Full Text] [PDF]

M. Lei, I. H. Cheng, L. A. Roberts, M. A. McAlear, and B. K. Tye
Two mcm3 Mutations Affect Different Steps in the Initiation of DNA Replication
J. Biol. Chem., August 16, 2002; 277(34): 30824 - 30831.
[Abstract] [Full Text] [PDF]

M. Yamada, N. Sato, C. Taniyama, K. Ohtani, K.-i. Arai, and H. Masai
A 63-Base Pair DNA Segment Containing an Sp1 Site but Not a Canonical E2F Site Can Confer Growth-dependent and E2F-mediated Transcriptional Stimulation of the Human ASK Gene Encoding the Regulatory Subunit for Human Cdc7-related Kinase
J. Biol. Chem., July 26, 2002; 277(31): 27668 - 27681.
[Abstract] [Full Text] [PDF]

A. D. Fung, J. Ou, S. Bueler, and G. W. Brown
A Conserved Domain of Schizosaccharomyces pombe dfp1+ Is Uniquely Required for Chromosome Stability following Alkylation Damage during S Phase
Mol. Cell. Biol., July 1, 2002; 22(13): 4477 - 4490.
[Abstract] [Full Text] [PDF]

R. A. Sclafani, M. Tecklenburg, and A. Pierce
The mcm5-bob1 Bypass of Cdc7p/Dbf4p in DNA Replication Depends on Both Cdk1-Independent and Cdk1-Dependent Steps in Saccharomyces cerevisiae
Genetics, May 1, 2002; 161(1): 47 - 57.
[Abstract] [Full Text] [PDF]

T. Nakamura, M. Nakamura-Kubo, T. Nakamura, and C. Shimoda
Novel Fission Yeast Cdc7-Dbf4-Like Kinase Complex Required for the Initiation and Progression of Meiotic Second Division
Mol. Cell. Biol., January 1, 2002; 22(1): 309 - 320.
[Abstract] [Full Text] [PDF]

Y. Ishimi, Y. Komamura-Kohno, K.-i. Arai, and H. Masai
Biochemical Activities Associated with Mouse Mcm2 Protein
J. Biol. Chem., November 9, 2001; 276(46): 42744 - 42752.
[Abstract] [Full Text] [PDF]

A. Vas, W. Mok, and J. Leatherwood
Control of DNA Rereplication via Cdc2 Phosphorylation Sites in the Origin Recognition Complex
Mol. Cell. Biol., September 1, 2001; 21(17): 5767 - 5777.
[Abstract] [Full Text] [PDF]

K. Stoeber, T. D. Tlsty, L. Happerfield, G. A. Thomas, S. Romanov, L. Bobrow, E. D. Williams, and G. H. Williams
DNA replication licensing and human cell proliferation
J. Cell Sci., January 6, 2001; 114(11): 2027 - 2041.
[Abstract] [Full Text] [PDF]

M Lei and B. Tye
Initiating DNA synthesis: from recruiting to activating the MCM complex
J. Cell Sci., January 4, 2001; 114(8): 1447 - 1454.
[Abstract] [PDF]

H. A. Snaith, G. W. Brown, and S. L. Forsburg
Schizosaccharomyces pombe Hsk1p Is a Potential Cds1p Target Required for Genome Integrity
Mol. Cell. Biol., November 1, 2000; 20(21): 7922 - 7932.
[Abstract] [Full Text]

J. C. Walter
Evidence for Sequential Action of cdc7 and cdk2 Protein Kinases during Initiation of DNA Replication in Xenopus Egg Extracts
J. Biol. Chem., December 8, 2000; 275(50): 39773 - 39778.
[Abstract] [Full Text] [PDF]

K. Ogino, T. Takeda, E. Matsui, H. Iiyama, C. Taniyama, K.-i. Arai, and H. Masai
Bipartite Binding of a Kinase Activator Activates Cdc7-related Kinase Essential for S Phase
J. Biol. Chem.,

				T. S. Takahashi, A. Basu, V. Bermudez, J. Hurwitz, and J. C. Walter Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts Genes & Dev., July 15, 2008; 22(14): 1894 - 1905. [Abstract] [Full Text] [PDF]

				E. Rampakakis, D. Di Paola, and M. Zannis-Hadjopoulos Ku is involved in cell growth, DNA replication and G1-S transition J. Cell Sci., March 1, 2008; 121(5): 590 - 600. [Abstract] [Full Text] [PDF]

				H. Murakami and S. Keeney Regulating the formation of DNA double-strand breaks in meiosis Genes & Dev., February 1, 2008; 22(3): 286 - 292. [Full Text] [PDF]

				L. Wan, H. Niu, B. Futcher, C. Zhang, K. M. Shokat, S. J. Boulton, and N. M. Hollingsworth Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast Genes & Dev., February 1, 2008; 22(3): 386 - 397. [Abstract] [Full Text] [PDF]

				S. Nambiar, A. Mirmohammadsadegh, M. Hassan, R. Mota, A. Marini, A. Alaoui, A. Tannapfel, J. H. Hegemann, and U. R. Hengge Identification and functional characterization of ASK/Dbf4, a novel cell survival gene in cutaneous melanoma with prognostic relevance Carcinogenesis, December 1, 2007; 28(12): 2501 - 2510. [Abstract] [Full Text] [PDF]

				M. L. Hoang, R. P. Leon, L. Pessoa-Brandao, S. Hunt, M. K. Raghuraman, W. L. Fangman, B. J. Brewer, and R. A. Sclafani Structural Changes in Mcm5 Protein Bypass Cdc7-Dbf4 Function and Reduce Replication Origin Efficiency in Saccharomyces cerevisiae Mol. Cell. Biol., November 1, 2007; 27(21): 7594 - 7602. [Abstract] [Full Text] [PDF]

				P. Tenca, D. Brotherton, A. Montagnoli, S. Rainoldi, C. Albanese, and C. Santocanale Cdc7 Is an Active Kinase in Human Cancer Cells Undergoing Replication Stress J. Biol. Chem., January 5, 2007; 282(1): 208 - 215. [Abstract] [Full Text] [PDF]

				H. Masai, C. Taniyama, K. Ogino, E. Matsui, N. Kakusho, S. Matsumoto, J.-M. Kim, A. Ishii, T. Tanaka, T. Kobayashi, et al. Phosphorylation of MCM4 by Cdc7 Kinase Facilitates Its Interaction with Cdc45 on the Chromatin J. Biol. Chem., December 22, 2006; 281(51): 39249 - 39261. [Abstract] [Full Text] [PDF]

				L. Wan, C. Zhang, K. M. Shokat, and N. M. Hollingsworth Chemical Inactivation of Cdc7 Kinase in Budding Yeast Results in a Reversible Arrest That Allows Efficient Cell Synchronization Prior to Meiotic Recombination Genetics, December 1, 2006; 174(4): 1767 - 1774. [Abstract] [Full Text] [PDF]

				P. R. Dohrmann and R. A. Sclafani Novel Role for Checkpoint Rad53 Protein Kinase in the Initiation of Chromosomal DNA Replication in Saccharomyces cerevisiae Genetics, September 1, 2006; 174(1): 87 - 99. [Abstract] [Full Text] [PDF]

				W.-H. Cho, Y.-J. Lee, S.-I. Kong, J. Hurwitz, and J.-K. Lee CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein PNAS, August 1, 2006; 103(31): 11521 - 11526. [Abstract] [Full Text] [PDF]

				C. Gabrielse, C. T. Miller, K. H. McConnell, A. DeWard, C. A. Fox, and M. Weinreich A Dbf4p BRCA1 C-Terminal-Like Domain Required for the Response to Replication Fork Arrest in Budding Yeast Genetics, June 1, 2006; 173(2): 541 - 555. [Abstract] [Full Text] [PDF]

				K. Ogino, K. Hirota, S. Matsumoto, T. Takeda, K. Ohta, K.-i. Arai, and H. Masai Hsk1 kinase is required for induction of meiotic dsDNA breaks without involving checkpoint kinases in fission yeast PNAS, May 23, 2006; 103(21): 8131 - 8136. [Abstract] [Full Text] [PDF]

				S. Matsumoto, K. Ogino, E. Noguchi, P. Russell, and H. Masai Hsk1-Dfp1/Him1, the Cdc7-Dbf4 Kinase in Schizosaccharomyces pombe, Associates with Swi1, a Component of the Replication Fork Protection Complex J. Biol. Chem., December 30, 2005; 280(52): 42536 - 42542. [Abstract] [Full Text] [PDF]

				N. R. May, M. Thomer, K. F. Murnen, and B. R. Calvi Levels of the origin-binding protein Double parked and its inhibitor Geminin increase in response to replication stress J. Cell Sci., September 15, 2005; 118(18): 4207 - 4217. [Abstract] [Full Text] [PDF]

				A. E. Varrin, A. A. Prasad, R.-P. Scholz, M. D. Ramer, and B. P. Duncker A Mutation in Dbf4 Motif M Impairs Interactions with DNA Replication Factors and Confers Increased Resistance to Genotoxic Agents Mol. Cell. Biol., September 1, 2005; 25(17): 7494 - 7504. [Abstract] [Full Text] [PDF]

				N. Yamashita, J.-M. Kim, O. Koiwai, K.-i. Arai, and H. Masai Functional analyses of mouse ASK, an activation subunit for Cdc7 kinase, using conditional ASK knockout ES cells Genes Cells, June 1, 2005; 10(6): 551 - 563. [Abstract] [Full Text] [PDF]

				N. Y. Su, K. Flick, and P. Kaiser The F-Box Protein Met30 Is Required for Multiple Steps in the Budding Yeast Cell Cycle Mol. Cell. Biol., May 15, 2005; 25(10): 3875 - 3885. [Abstract] [Full Text] [PDF]

				H. Fujii-Yamamoto, J. M. Kim, K.-i. Arai, and H. Masai Cell Cycle and Developmental Regulations of Replication Factors in Mouse Embryonic Stem Cells J. Biol. Chem., April 1, 2005; 280(13): 12976 - 12987. [Abstract] [Full Text] [PDF]

				N. Yoshizawa-Sugata, A. Ishii, C. Taniyama, E. Matsui, K.-i. Arai, and H. Masai A Second Human Dbf4/ASK-related Protein, Drf1/ASKL1, Is Required for Efficient Progression of S and M Phases J. Biol. Chem., April 1, 2005; 280(13): 13062 - 13070. [Abstract] [Full Text] [PDF]

				M. Volkening and I. Hoffmann Involvement of Human MCM8 in Prereplication Complex Assembly by Recruiting hcdc6 to Chromatin Mol. Cell. Biol., February 15, 2005; 25(4): 1560 - 1568. [Abstract] [Full Text] [PDF]

				D. Shechter, C. Y. Ying, and J. Gautier DNA Unwinding Is an MCM Complex-dependent and ATP Hydrolysis-dependent Process J. Biol. Chem., October 29, 2004; 279(44): 45586 - 45593. [Abstract] [Full Text] [PDF]

				A. Montagnoli, P. Tenca, F. Sola, D. Carpani, D. Brotherton, C. Albanese, and C. Santocanale Cdc7 Inhibition Reveals a p53-Dependent Replication Checkpoint That Is Defective in Cancer Cells Cancer Res., October 1, 2004; 64(19): 7110 - 7116. [Abstract] [Full Text] [PDF]

				M. Thomer, N. R. May, B. D. Aggarwal, G. Kwok, and B. R. Calvi Drosophila double-parked is sufficient to induce re-replication during development and is regulated by cyclin E/CDK2 Development, October 1, 2004; 131(19): 4807 - 4818. [Abstract] [Full Text] [PDF]

				Y. Kinoshita and E. M. Johnson Site-specific Loading of an MCM Protein Complex in a DNA Replication Initiation Zone Upstream of the c-MYC Gene in the HeLa Cell Cycle J. Biol. Chem., August 20, 2004; 279(34): 35879 - 35889. [Abstract] [Full Text] [PDF]

				L. Pessoa-Brandao and R. A. Sclafani CDC7/DBF4 Functions in the Translesion Synthesis Branch of the RAD6 Epistasis Group in Saccharomyces cerevisiae Genetics, August 1, 2004; 167(4): 1597 - 1610. [Abstract] [Full Text] [PDF]

				K. Fien, Y.-S. Cho, J.-K. Lee, S. Raychaudhuri, I. Tappin, and J. Hurwitz Primer Utilization by DNA Polymerase {alpha}-Primase Is Influenced by Its Interaction with Mcm10p J. Biol. Chem., April 16, 2004; 279(16): 16144 - 16153. [Abstract] [Full Text] [PDF]

				S. L. Forsburg Eukaryotic MCM Proteins: Beyond Replication Initiation Microbiol. Mol. Biol. Rev., March 1, 2004; 68(1): 109 - 131. [Abstract] [Full Text] [PDF]

				A. Koc, L. J. Wheeler, C. K. Mathews, and G. F. Merrill Hydroxyurea Arrests DNA Replication by a Mechanism That Preserves Basal dNTP Pools J. Biol. Chem., January 2, 2004; 279(1): 223 - 230. [Abstract] [Full Text] [PDF]

				J. Gregan, K. Lindner, L. Brimage, R. Franklin, M. Namdar, E. A. Hart, S. J. Aves, and S. E. Kearsey Fission Yeast Cdc23/Mcm10 Functions after Pre-replicative Complex Formation To Promote Cdc45 Chromatin Binding Mol. Biol. Cell, September 1, 2003; 14(9): 3876 - 3887. [Abstract] [Full Text] [PDF]