Chromatin-bound Cdc6 persists in S and G2 phases in human cells, while soluble Cdc6 is destroyed in a cyclin A-cdk2 dependent process

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				L. R. Borlado and J. Mendez CDC6: from DNA replication to cell cycle checkpoints and oncogenesis Carcinogenesis, February 1, 2008; 29(2): 237 - 243. [Abstract] [Full Text] [PDF]

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				K. K. Imai, Y. Ohashi, T. Tsuge, T. Yoshizumi, M. Matsui, A. Oka, and T. Aoyama The A-Type Cyclin CYCA2;3 Is a Key Regulator of Ploidy Levels in Arabidopsis Endoreduplication PLANT CELL, February 1, 2006; 18(2): 382 - 396. [Abstract] [Full Text] [PDF]

				L.-C. Chuang and P. R. Yew Proliferating Cell Nuclear Antigen Recruits Cyclin-dependent Kinase Inhibitor Xic1 to DNA and Couples Its Proteolysis to DNA Polymerase Switching J. Biol. Chem., October 21, 2005; 280(42): 35299 - 35309. [Abstract] [Full Text] [PDF]

				N. R. May, M. Thomer, K. F. Murnen, and B. R. Calvi Levels of the origin-binding protein Double parked and its inhibitor Geminin increase in response to replication stress J. Cell Sci., September 15, 2005; 118(18): 4207 - 4217. [Abstract] [Full Text] [PDF]

				A. Duursma and R. Agami p53-Dependent Regulation of Cdc6 Protein Stability Controls Cellular Proliferation Mol. Cell. Biol., August 15, 2005; 25(16): 6937 - 6947. [Abstract] [Full Text] [PDF]

				N Murphy, M Ring, C C B B Heffron, B King, A G Killalea, C Hughes, C M Martin, E McGuinness, O Sheils, and J J O'Leary p16INK4A, CDC6, and MCM5: predictive biomarkers in cervical preinvasive neoplasia and cervical cancer J. Clin. Pathol., May 1, 2005; 58(5): 525 - 534. [Abstract] [Full Text] [PDF]

				M. Volkening and I. Hoffmann Involvement of Human MCM8 in Prereplication Complex Assembly by Recruiting hcdc6 to Chromatin Mol. Cell. Biol., February 15, 2005; 25(4): 1560 - 1568. [Abstract] [Full Text] [PDF]

				D. Coverley, J. Marr, and J. Ainscough Ciz1 promotes mammalian DNA replication J. Cell Sci., January 1, 2005; 118(1): 101 - 112. [Abstract] [Full Text] [PDF]

				M. Anger, P. Stein, and R. M. Schultz CDC6 Requirement for Spindle Formation During Maturation of Mouse Oocytes Biol Reprod, January 1, 2005; 72(1): 188 - 194. [Abstract] [Full Text] [PDF]

				P. Karakaidos, S. Taraviras, L. V. Vassiliou, P. Zacharatos, N. G. Kastrinakis, D. Kougiou, M. Kouloukoussa, H. Nishitani, A. G. Papavassiliou, Z. Lygerou, et al. Overexpression of the Replication Licensing Regulators hCdt1 and hCdc6 Characterizes a Subset of Non-Small-Cell Lung Carcinomas: Synergistic Effect with Mutant p53 on Tumor Growth and Chromosomal Instability--Evidence of E2F-1 Transcriptional Control over hCdt1 Am. J. Pathol., October 1, 2004; 165(4): 1351 - 1365. [Abstract] [Full Text] [PDF]

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				Y. Ofir, S. Sagee, N. Guttmann-Raviv, L. Pnueli, and Y. Kassir The Role and Regulation of the preRC Component Cdc6 in the Initiation of Premeiotic DNA Replication Mol. Biol. Cell, May 1, 2004; 15(5): 2230 - 2242. [Abstract] [Full Text] [PDF]

				M. Oehlmann, A. J. Score, and J. J. Blow The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation J. Cell Biol., April 26, 2004; 165(2): 181 - 190. [Abstract] [Full Text] [PDF]

				M. G. Alexandrow and J. L. Hamlin Cdc6 Chromatin Affinity Is Unaffected by Serine-54 Phosphorylation, S-Phase Progression, and Overexpression of Cyclin A Mol. Cell. Biol., February 15, 2004; 24(4): 1614 - 1627. [Abstract] [Full Text] [PDF]

				J. P. H. Chow, W. Y. Siu, H. T. B. Ho, K. H. T. Ma, C. C. Ho, and R. Y. C. Poon Differential Contribution of Inhibitory Phosphorylation of CDC2 and CDK2 for Unperturbed Cell Cycle Control and DNA Integrity Checkpoints J. Biol. Chem., October 17, 2003; 278(42): 40815 - 40828. [Abstract] [Full Text] [PDF]

				X. Li, Q. Zhao, R. Liao, P. Sun, and X. Wu The SCFSkp2 Ubiquitin Ligase Complex Interacts with the Human Replication Licensing Factor Cdt1 and Regulates Cdt1 Degradation J. Biol. Chem., August 15, 2003; 278(33): 30854 - 30858. [Abstract] [Full Text] [PDF]

				N. Biswas, V. Sanchez, and D. H. Spector Human Cytomegalovirus Infection Leads to Accumulation of Geminin and Inhibition of the Licensing of Cellular DNA Replication J. Virol., February 15, 2003; 77(4): 2369 - 2376. [Abstract] [Full Text] [PDF]

				S. Martins, S. Eikvar, K. Furukawa, and P. Collas HA95 and LAP2{beta} mediate a novel chromatin-nuclear envelope interaction implicated in initiation of DNA replication J. Cell Biol., January 21, 2003; 160(2): 177 - 188. [Abstract] [Full Text] [PDF]

				F. Borel, F. B. Lacroix, and R. L. Margolis Prolonged arrest of mammalian cells at the G1/S boundary results in permanent S phase stasis J. Cell Sci., July 15, 2002; 115(14): 2829 - 2838. [Abstract] [Full Text] [PDF]

				S. Geley, E. Kramer, C. Gieffers, J. Gannon, J.-M. Peters, and T. Hunt Anaphase-promoting Complex/Cyclosome-dependent Proteolysis of Human Cyclin A Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint J. Cell Biol., April 2, 2001; 153(1): 137 - 148. [Abstract] [Full Text] [PDF]

				K. V. Kibler and K.-T. Jeang CREB/ATF-Dependent Repression of Cyclin A by Human T-Cell Leukemia Virus Type 1 Tax Protein J. Virol., March 1, 2001; 75(5): 2161 - 2173. [Abstract] [Full Text]

				H. Laman, D. Coverley, T. Krude, R. Laskey, and N. Jones Viral Cyclin-Cyclin-Dependent Kinase 6 Complexes Initiate Nuclear DNA Replication Mol. Cell. Biol., January 15, 2001; 21(2): 624 - 635. [Abstract] [Full Text]

				M Lei and B. Tye Initiating DNA synthesis: from recruiting to activating the MCM complex J. Cell Sci., January 4, 2001; 114(8): 1447 - 1454. [Abstract] [PDF]

				J. Méndez and B. Stillman Chromatin Association of Human Origin Recognition Complex, Cdc6, and Minichromosome Maintenance Proteins during the Cell Cycle: Assembly of Prereplication Complexes in Late Mitosis Mol. Cell. Biol., November 15, 2000; 20(22): 8602 - 8612. [Abstract] [Full Text]

				C. Pelizon, M. A. Madine, P. Romanowski, and R. A. Laskey Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle Genes & Dev., October 1, 2000; 14(19): 2526 - 2533. [Abstract] [Full Text]

				Y. Ishimi and Y. Komamura-Kohno Phosphorylation of Mcm4 at Specific Sites by Cyclin-dependent Kinase Leads to Loss of Mcm4,6,7 Helicase Activity J. Biol. Chem., September 7, 2001; 276(37): 34428 - 34433. [Abstract] [Full Text] [PDF]

				H. Nishitani, S. Taraviras, Z. Lygerou, and T. Nishimoto The Human Licensing Factor for DNA Replication Cdt1 Accumulates in G1 and Is Destabilized after Initiation of S-phase J. Biol. Chem., November 21, 2001; 276(48): 44905 - 44911. [Abstract] [Full Text] [PDF]