The Ku70 autoantigen interacts with p40phox in B lymphocytes

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Grandvaux, N.
	Articles by Dagher, M. C.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Grandvaux, N.
	Articles by Dagher, M. C.

Abo, A., Boyhan, A., West, I., Thrasher, A. J. and Segal, A. W (1992). Reconstitution of neutrophil NADPH oxidase activity in the cell-free system by four components: p67-phox, p47-phox, p21rac1, and cytochrome b-245. J. Biol. Chem 267, 16767-16770.[Abstract/Free Full Text]

Ajmani, A. K., Satoh, M., Reap, E., Cohen, P. L. and Reeves, W. H (1995). Absence of autoantigen Ku in mature human neutrophils and humanpromyelocytic leukemia line (HL-60) cells and lymphocytes undergoing apoptosis. J. Exp. Med 181, 2049-2058.[Abstract/Free Full Text]

Altschul, S. F., Gish, W., Miller, W., Myers, E. W. and Lipman, D. J (1990). Basic local alignment search tool. J. Mol. Biol 215, 403-410.[Medline]

Anderson, C. W (1993). DNA damage and the DNA-activated protein kinase. Trends Biochem. Sci 18, 433-437.[Medline]

Aruffo, A. and Seed, B (1987). Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc. Natl. Acad. Sci. USA 84, 8573-8577.[Abstract/Free Full Text]

Bandyopadhyay, D., Mandal, M., Adam, L., Mendelsohn, J. and Kumar, R (1998). Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells. J. Biol. Chem 273, 1568-1573.[Abstract/Free Full Text]

Bannister, A. J., Gottlieb, T. M., Kouzarides, T. and Jackson, S. P (1993). c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif. Nucleic Acids Res 21, 1289-1295.[Abstract/Free Full Text]

Barlev, N. A., Poltoratsky, V., Owen-Hughes, T., Ying, C., Liu, L., Workman, J. L. and Berger, S. L (1998). Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol. Cell Biol 18, 1349-1358.[Abstract/Free Full Text]

Blunt, T., Finnie, N. J., Taccioli, G. E., Smith, G. C., Demengeot, J., Gottlieb, T. M., Mizuta, R., Varghese, A. J., Alt, F. W., Jeggo, P. A., et al (1995). Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 80, 813-823.[Medline]

Carter, T., Vancurova, I., Sun, I., Lou, W. and DeLeon, S (1990). A DNA-activated protein kinase from HeLa cell nuclei. Mol. Cell. Biol 10, 6460-6471.[Abstract/Free Full Text]

Chan, D. C., Bedford, M. T. and Leder, P (1996). Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J 15, 1045-1054.[Medline]

Cohen-Tanugi, L., Morel, F., Pilloud-Dagher, M. C., Seigneurin, J. M., Francois, P., Bost, M. and Vignais, P. V (1991). Activation of O2()-generating oxidase in an heterologous cell-free system derived from Epstein-Barr-virus-transformed human B lymphocytes and bovine neutrophils. Application to the study of defects in cytosolic factors in chronic granulomatous disease. Eur. J. Biochem 202, 649-655.[Medline]

Dvir, A., Stein, L. Y., Calore, B. L. and Dynan, W. S (1993). Purification and characterization of a template-associated protein kinase that phosphorylates RNA polymerase II. J. Biol. Chem 268, 10440-10447.[Abstract/Free Full Text]

Dynan, W. S. and Yoo, S (1998). Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids. Nucleic Acids Res 26, 1551-1559.[Abstract/Free Full Text]

Einbond, A. and Sudol, M (1996). Towards prediction of cognate complexes between the WW domain and proline-rich ligands. FEBS Lett 384, 1-8.[Medline]

Elango, N., Vivekananda, J., Strong, R. and Katz, M. S (1997). Nuclei isolation from bone cells for nuclear run-on assays. Biotechniques 23, 422-424.[Medline]

Estojak, J., Brent, R. and Golemis, E. A (1995). Correlation of two-hybrid affinity data with in vitro measurements. Mol. Cell. Biol 15, 5820-5829.[Abstract]

Falzon, M., Fewell, J. W. and Kuff, E. L (1993). EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single-to double-strand transitions in DNA. J. Biol. Chem 268, 10546-10552.[Abstract/Free Full Text]

Fewell, J. W. and Kuff, E. L (1996). Intracellular redistribution of Ku immunoreactivity in response to cell-cell contact and growth modulating components in the medium. J. Cell Sci 109, 1937-1946.[Abstract]

Fuchs, A., Bouin, A. P., Rabilloud, T. and Vignais, P. V (1997). The 40-kDa component of the phagocyte NADPH oxidase (p40phox) is phosphorylated during activation in differentiated HL60 cells. Eur. J. Biochem 249, 531-539.[Medline]

Fuchs, A., Dagher, M. C., Faure, J. and Vignais, P. V (1996). Topological organization of the cytosolic activating complex of the superoxide-generating NADPH-oxidase. Pinpointing the sites of interaction between p47phoz, p67phox and p40phox using the two-hybrid system. Biochim. Biophys. Acta 1312, 39-47.[Medline]

Fuchs, A., Dagher, M. C., Jouan, A. and Vignais, P. V (1994). Activation of the O2()-generating NADPH oxidase in a semi-recombinant cell-free system. Assessment of the function of Rac in the activation process. Eur. J. Biochem 226, 587-595.[Medline]

Fuchs, A., Dagher, M. C. and Vignais, P. V (1995). Mapping the domains of interaction of p40phox with both p47phox and p67phox of the neutrophil oxidase complex using the two-hybrid system. J. Biol. Chem 270, 5695-5697.[Abstract/Free Full Text]

Giffin, W., Kwast-Welfeld, J., Rodda, D. J., Prefontaine, G. G., Traykova-Andonova, M., Zhang, Y., Weigel, N. L., Lefebvre, Y. A. and Hache, R. J (1997). Sequence-specific DNA binding and transcription factor phosphorylation by Ku Autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor. J. Biol. Chem 272, 5647-5658.[Abstract/Free Full Text]

Giffin, W., Torrance, H., Rodda, D. J., Prefontaine, G. G., Pope, L. and Hache, R. J (1996). Sequence-specific DNA binding by Ku autoantigen and its effects on transcription. Nature 380, 265-268.[Medline]

Gottlieb, T. M. and Jackson, S. P (1993). The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen. Cell 72, 131-142.[Medline]

Grawunder, U., Finnie, N., Jackson, S. P., Riwar, B. and Jessberger, R (1996). Expression of DNA-dependent protein kinase holoenzyme upon induction of lymphocyte differentiation and V(D)J recombination. Eur. J. Biochem 241, 931-940.[Medline]

Griffith, A. J., Blier, P. R., Mimori, T. and Hardin, J. A (1992). Ku polypeptides synthesized in vitro assemble into complexes which recognize ends of double-stranded DNA. J. Biol. Chem 267, 331-338.[Abstract/Free Full Text]

Hammarsten, O. and Chu, G (1998). DNA-dependent protein kinase: DNA binding and activation in the absence of Ku. Proc. Natl. Acad. Sci. USA 95, 525-530.[Abstract/Free Full Text]

Hartley, K. O., Gell, D., Smith, G. C., Zhang, H., Divecha, N., Connelly, M. A., Admon, A., Lees-Miller, S. P., Anderson, C. W. and Jackson, S. P (1995). DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell 82, 849-856.[Medline]

Henderson, L. M. and Chappel, J. B (1996). NADPH oxidase of neutrophils. Biochim. Biophys. Acta 1273, 87-107.[Medline]

Higashiura, M., Shimizu, Y., Tanimoto, M., Morita, T. and Yagura, T (1992). Immunolocalization of Ku-proteins (p80/p70): localization of p70 to nucleoli and periphery of both interphase nuclei and metaphase chromosomes. Exp. Cell Res 201, 444-451.[Medline]

Hollenberg, S. M., Sternglanz, R., Cheng, P. F. and Weintraub, H (1995). Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol. Cell Biol 15, 3813-3822.[Abstract]

Jackson, S. P. and Jeggo, P. A (1995). DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends Biochem. Sci 20, 412-415.[Medline]

Lees-Miller, S. P., Chen, Y. R. and Anderson, C. W (1990). Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen. Mol. Cell. Biol 10, 6472-6481.[Abstract/Free Full Text]

Lees-Miller, S. P., Godbout, R., Chan, D. W., Weinfeld, M., Day, R. S. R., Barron, G. M. and Allalunis-Turner, J (1995). Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line. Science 267, 1183-1185.[Abstract/Free Full Text]

Li, G. C., Yang, S. H., Kim, D., Nussenzweig, A., Ouyang, H., Wei, J., Burgman, P. and Li, L (1995). Suppression of heat-induced hsp70 expression by the 70-kDa subunit of the human Ku autoantigen. Proc. Natl. Acad. Sci. USA 92, 4512-4516.[Abstract/Free Full Text]

Maly, F. E., Cross, A. R., Jones, O. T., Wolf-Vorbeck, G., Walker, C., Dahinden, C. A. and De Weck, A. L (1988). The superoxide generating system of B cell lines. Structural homology with the phagocytic oxidase and triggering via surface Ig. J. Immunol 140, 2334-2339.[Abstract]

Mimori, T. and Hardin, J. A (1986). Mechanism of interaction between Ku protein and DNA. J. Biol. Chem 261, 10375-10379.[Abstract/Free Full Text]

Mizuki, K., Kadomatsu, K., Hata, K., Ito, T., Fan, Q. W., Kage, Y., Fukumaki, Y., Sakaki, Y., Takeshige, K. and Sumimoto, H (1998). Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex. Eur. J. Biochem 251, 573-582.[Medline]

Morel, F., Cohen Tanugi Cholley, L., Brandolin, G., Dianoux, A. C., Martel, C., Champelovier, P., Seigneurin, J. M., Francois, P., Bost, M. and Vignais, P. V (1993). The O2generating oxidase of B lymphocytes: Epstein-Barr virus-immortalized B lymphocytes as a tool for the identification of defective components of the oxidase in chronic granulomatous disease. Biochim. Biophys. Acta 1182, 101-109.[Medline]

Nakamura, R., Sumimoto, H., Mizuki, K., Hata, K., Ago, T., Kitajima, S., Takeshige, K., Sakaki, Y. and Ito, T (1998). The PC motif: a novel and evolutionarily conserved sequence involved in interaction between p40phox and p67phox, SH3 domain-containing cytosolic factors of the phagocyte NADPH oxidase. Eur. J. Biochem 251, 583-589.[Medline]

Ochem, A. E., Skopac, D., Costa, M., Rabilloud, T., Vuillard, L., Simoncsits, A., Giacca, M. and Falaschi, A (1997). Functional properties of the separate subunits of human DNA helicase II/Ku autoantigen. J. Biol. Chem 272, 29919-29926.[Abstract/Free Full Text]

Ono, M., Tucker, P. W. and Capra, J. D (1996). Ku is a general inhibitor of DNA-protein complex formation and transcription. Mol. Immunol 33, 787-796.[Medline]

Reeves, W. H (1992). Antibodies to the p70/p80 (Ku) antigens in systemic lupus erythematosus. Rheum. Dis. Clin. North Am 18, 391-414.[Medline]

Romero, F., Dargemont, C., Pozo, F., Reeves, W. H., Camonis, J., Gisselbrecht, S. and Fischer, S (1996). p95vav associates with the nuclear protein Ku-70. Mol. Cell. Biol 16, 37-44.[Abstract]

Rotrosen, D., Yeung, C. L., Leto, T. L., Malech, H. L. and Kwong, C. H (1992). Cytochrome b558: the flavin-binding component of the phagocyte NADPH oxidase. Science 256, 1459-1462.[Abstract/Free Full Text]

Sathyamoorthy, M., de Mendez, I., Adams, A. G. and Leto, T. L (1997). p40(phox) Down-regulates NADPH Oxidase Activity through Interactions with Its SH3 Domain. J. Biol. Chem 272, 9141-9146.[Abstract/Free Full Text]

Taccioli, G. E., Gottlieb, T. M., Blunt, T., Priestley, A., Demengeot, J., Mizuta, R., Lehmann, A. R., Alt, F. W., Jackson, S. P. and Jeggo, P. A (1994). Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 265, 1442-1445.[Abstract/Free Full Text]

Thrasher, A. J., Keep, N. H., Wientjes, F. and Segal, A. W (1994). Chronic granulomatous disease. Biochim. Biophys. Acta 1227, 1-24.[Medline]

Tuteja, N., Tuteja, R., Ochem, A., Taneja, P., Huang, N. W., Simoncsits, A., Susic, S., Rahman, K., Marusic, L., Chen, J. and et al (1994). Human DNA helicase II: a novel DNA unwinding enzyme identified as the Ku autoantigen. EMBO J 13, 4991-5001.[Medline]

Van Aelst, L., Barr, M., Marcus, S., Polverino, A. and Wigler, M (1993). Complex formation between RAS and RAF and other protein kinases. Proc. Natl. Acad. Sci. USA 90, 6213-6217.[Abstract/Free Full Text]

Vojtek, A. B., Hollenberg, S. M. and Cooper, J. A (1993). Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74, 205-214.[Medline]

Wen, W., Meinkoth, J. L., Tsien, R. Y. and Taylor, S. S (1995). Identification of a signal for rapid export of proteins from the nucleus. Cell 82, 463-473.[Medline]

Yaneva, M. and Jhiang, S (1991). Expression of the Ku protein during cell proliferation. Biochim. Biophys. Acta 1090, 181-187.[Medline]

Yaneva, M., Kowalewski, T. and Lieber, M. R (1997). Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies. EMBO J 16, 5098-5112.[Medline]

Yang, S. H., Nussenzweig, A., Li, L., Kim, D., Ouyang, H., Burgman, P. and Li, G. C (1996). Modulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits. Mol. Cell. Biol 16, 3799-3806.[Abstract]

Zhan, S., Vazquez, N., Zhan, S., Wientjes, F. B., Budarf, M. L., Schrock, E., Ried, T., Green, E. D. and Chanock, S. J (1996). Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex. Blood 88, 2714-2721.[Abstract/Free Full Text]

This article has been cited by other articles:

A. Orient, A. Donko, A. Szabo, T. L. Leto, and M. Geiszt
Novel sources of reactive oxygen species in the human body
Nephrol. Dial. Transplant., May 1, 2007; 22(5): 1281 - 1288.
[Full Text] [PDF]

K. Bedard and K.-H. Krause
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
Physiol Rev, January 1, 2007; 87(1): 245 - 313.
[Abstract] [Full Text] [PDF]

C. D. Ellson, K. Davidson, G. J. Ferguson, R. O'Connor, L. R. Stephens, and P. T. Hawkins
Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing
J. Exp. Med., August 7, 2006; 203(8): 1927 - 1937.
[Abstract] [Full Text] [PDF]

M. Geiszt
NADPH oxidases: New kids on the block
Cardiovasc Res, July 15, 2006; 71(2): 289 - 299.
[Abstract] [Full Text] [PDF]

C. Massenet, S. Chenavas, C. Cohen-Addad, M.-C. Dagher, G. Brandolin, E. Pebay-Peyroula, and F. Fieschi
Effects of p47phox C Terminus Phosphorylations on Binding Interactions with p40phox and p67phox: STRUCTURAL AND FUNCTIONAL COMPARISON OF p40phox and p67phox SH3 DOMAINS
J. Biol. Chem., April 8, 2005; 280(14): 13752 - 13761.
[Abstract] [Full Text] [PDF]

H. Lucero, D. Gae, and G. E. Taccioli
Novel Localization of the DNA-PK Complex in Lipid Rafts: A PUTATIVE ROLE IN THE SIGNAL TRANSDUCTION PATHWAY OF THE IONIZING RADIATION RESPONSE
J. Biol. Chem., June 6, 2003; 278(24): 22136 - 22143.
[Abstract] [Full Text] [PDF]

K. D. Brown, T. A. Lataxes, S. Shangary, J. L. Mannino, J. F. Giardina, J. Chen, and R. Baskaran
Ionizing Radiation Exposure Results in Up-regulation of Ku70 via a p53/Ataxia-Telangiectasia-mutated Protein-dependent Mechanism
J. Biol. Chem., February 25, 2000; 275(9): 6651 - 6656.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Grandvaux, N.

Articles by Dagher, M. C.

Search for Related Content

PubMed

PubMed Citation

Articles by Grandvaux, N.

Articles by Dagher, M. C.

				K. Bedard and K.-H. Krause The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology Physiol Rev, January 1, 2007; 87(1): 245 - 313. [Abstract] [Full Text] [PDF]

				C. D. Ellson, K. Davidson, G. J. Ferguson, R. O'Connor, L. R. Stephens, and P. T. Hawkins Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing J. Exp. Med., August 7, 2006; 203(8): 1927 - 1937. [Abstract] [Full Text] [PDF]

				M. Geiszt NADPH oxidases: New kids on the block Cardiovasc Res, July 15, 2006; 71(2): 289 - 299. [Abstract] [Full Text] [PDF]

				C. Massenet, S. Chenavas, C. Cohen-Addad, M.-C. Dagher, G. Brandolin, E. Pebay-Peyroula, and F. Fieschi Effects of p47phox C Terminus Phosphorylations on Binding Interactions with p40phox and p67phox: STRUCTURAL AND FUNCTIONAL COMPARISON OF p40phox and p67phox SH3 DOMAINS J. Biol. Chem., April 8, 2005; 280(14): 13752 - 13761. [Abstract] [Full Text] [PDF]

				H. Lucero, D. Gae, and G. E. Taccioli Novel Localization of the DNA-PK Complex in Lipid Rafts: A PUTATIVE ROLE IN THE SIGNAL TRANSDUCTION PATHWAY OF THE IONIZING RADIATION RESPONSE J. Biol. Chem., June 6, 2003; 278(24): 22136 - 22143. [Abstract] [Full Text] [PDF]

				K. D. Brown, T. A. Lataxes, S. Shangary, J. L. Mannino, J. F. Giardina, J. Chen, and R. Baskaran Ionizing Radiation Exposure Results in Up-regulation of Ku70 via a p53/Ataxia-Telangiectasia-mutated Protein-dependent Mechanism J. Biol. Chem., February 25, 2000; 275(9): 6651 - 6656. [Abstract] [Full Text] [PDF]