Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Trinczek, B.
	Articles by Mandelkow, E.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Trinczek, B.
	Articles by Mandelkow, E.

Barlow, S., Gonzalez-Garay, M. L., West, R. R., Olmsted, J. B. and Cabral, F (1994). Stable expression of heterologous microtubule-associatedproteins (MAPs) in chinese-hamster ovary cells \320 evidence for differing roles of MAPs in microtubule organization. J. Cell Biol 126, 1017-1029.[Abstract/Free Full Text]

Binder, L. I., Frankfurter, A. and Rebhun, L (1985). The distribution of tau in the mammalian central nervous system. J. Cell Biol 101, 1371-1378.[Abstract/Free Full Text]

Blocker A., Griffiths G., Olivo J. C., Hyman A. A. and Severin F. F (1998). A role for microtubule dynamics in phagosome movement. J. Cell Sci 111, 303-312.[Abstract]

Brady, S. T (1995). Biochemical and functional diversity of microtubule motors in the nervous system. Curr. Opin. Neurobiol 5, 551-558.[Medline]

Brandt, R., Leger, J. and Lee, G (1995). Interaction of tau with the neural plasma-membrane mediated by tau amino-terminal projection domain. J. Cell Biol 131, 1327-1340.[Abstract/Free Full Text]

Bulinski, J. C. and Borisy, G. G (1980). Immunofluorescence localization of HeLa cell microtubule-associated proteins on microtubules in vitro and in vivo. J. Cell Biol 87, 792-801.[Abstract/Free Full Text]

Bulinski, J. C., McGraw, T. E., Gruber, D., Nguyen, H.-L. and Sheetz, M. P (1997). Overexpression of MAP4 inhibits organelle motility and trafficking in vivo. J. Cell Sci 110, 3055-3064.[Abstract]

Burkhardt, J. K., Echeverri, C. J., Nilsson, T. and Vallee, R. B (1997). Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J. Cell Biol 139, 469-484.[Abstract/Free Full Text]

Chapin, S. J. and Bulinski, J. C (1991). Non-neuronal 210 kD Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau. J. Cell Sci 98, 27-36.[Abstract/Free Full Text]

Chen, J., Kanai, Y. and Hirokawa, N (1992). Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons. Nature 360, 674-677.[Medline]

DeBrabander,M., Geuens,G., Nuydens,R., Willebrords,R., Aerts,F. and DeMey, J (1986). Microtubule dynamics during the cell cycle: the effects of taxol and nocodazole on the microtubule system of PtK2cells at different stages of the mitotic cycle. Int. Rev. Cytol 101, 215-274.[Medline]

Drewes, G., Ebneth, A., Preuss, U., Mandelkow, E.-M. and Mandelkow, E (1997). MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption. Cell 89, 297-308.[Medline]

Drubin, D. G., Feinstein, S. C., Shooter, E. M. and Kirschner, M. W (1985). Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors. J. Cell Biol 101, 1799-1807.[Abstract/Free Full Text]

Drubin, D. G. and Nelson, W. J (1996). Origins of cell polarity. Cell 84, 335-344.[Medline]

Ebneth, A., Godemann, R., Stamer, K., Illenberger, S., Trinczek, B., Mandelkow, E.-M. and Mandelkow, E (1998). Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: implication for Alzheimer's disease. J. Cell Biol 143, 777-794.[Abstract/Free Full Text]

Feiguin, F., Ferreira, A., Kosik, K. S. and Caceres, A (1994). Kinesin-mediated organelle translocation revealed by specific cellular manipulations. J. Cell Biol 127, 1021-1039.[Abstract/Free Full Text]

Field J., Nikawa J., Broek D., MacDonald B., Rodgers L., Wilson I. A., Lerner R. A. and Wigler M (1988). Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Mol. Cell Biol 8, 2159-2165.[Abstract/Free Full Text]

Goedert, M., Spillantini, M. G., Potier, M. C., Ulrich, J. and Crowther, R. A (1989). Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. EMBO J 8, 393-399.[Medline]

Goodson, H. V., Valetti, C. and Kreis, T. E (1997). Motors and membrane traffic. Curr. Opin. Cell Biol 9, 18-28.[Medline]

Gustke, N., Trinczek, B., Biernat, J., Mandelkow, E.-M. and Mandelkow, E (1994). Domains of tau protein and interactions with microtubules. Biochemistry 33, 9511-9522.[Medline]

Gyoeva, F. K. and Gelfand, V. I (1991). Coalignment of vimentin intermediate filaments with microtubules depends on kinesin. Nature 353, 445-448.[Medline]

Hamm-Alvarez, S. F., Kim, P. Y. and Sheetz, M. P (1993). Regulation of vesicle transport in CV-1 cells and extracts. J. Cell Sci 106, 955-966.[Abstract]

Hagiwara, H., Yorifuji, H., Sato-Yoshitake, R. and Hirokawa, N (1994). Competition between motor molecules (kinesin and cytoplasmic dynein) and fibrous microtubule-associated proteins in binding to microtubules. J. Biol. Chem 269, 3581-3589.[Abstract/Free Full Text]

Hiller, G. and Weber, K (1978). Radioimmunoassay for tubulin: a quantitative comparison of the tubulin content of different established tissue culture cells and tissues. Cell 14, 795-804.[Medline]

Hirokawa, N (1994). Microtubule-organization and dynamics dependent on microtubule-associated proteins. Curr. Opin. Cell Biol 6, 74-81.[Medline]

Hirokawa, N (1998). Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 279, 519-526.[Abstract/Free Full Text]

Hollenbeck P. J., Bershadsky A. D., Pletjushkina O. Y., Tint I. S. and Vasiliev J. M (1989). Intermediate filament collapse is an ATP-dependent and actin-dependent process. J. Cell Sci 92, 621-631.[Abstract/Free Full Text]

Hollenbeck, P. and Swanson, J (1990). Radial extension of macrophage tubular lysosomes supported by kinesin. Nature 346, 864-866.[Medline]

Hyman A. and Karsenti E (1996). Morphogenetic properties of microtubules and mitotic spindle assembly. Cell 9, 401-410.

Illenberger S., Zheng-Fischhofer Q., Preuss U., Stamer K., Baumann K., Trinczek B., Biernat J., Godemann R., Mandelkow E. M. and Mandelkow E (1998). The endogenous and cell cycle-dependent phosphorylation of tau protein in living cells: implications for Alzheimer's disease. Mol. Biol. Cell 9, 1495-1512.[Abstract/Free Full Text]

Kamimura, S. and Mandelkow, E (1992). Tubulin protofilaments and kinesin-dependent motility. J. Cell Biol 118, 865-875.[Abstract/Free Full Text]

Kanai Y. and Hirokawa N (1995). Sorting mechanisms of tau and MAP2 in neurons: suppressed axonal transit of MAP2 and locally regulated microtubule binding. Neuron 14, 421-432.[Medline]

Khodjakov A., Lizunova E. M., Minin A. A., Koonce M. P. and Gyoeva F. K (1998). A specific light chain of kinesin associates with mitochondria in cultured cells. Mol. Biol. Cell 9, 333-343.[Abstract/Free Full Text]

Klymkowsky, M. W (1995). Intermediate filaments: new proteins, some answers, more questions. Curr. Opin. Cell Biol 7, 46-54.[Medline]

Kumar J., Yu, H. and Sheetz, M. P (1995). Kinectin, an essential anchor for kinesin-driven vesicle motility. Science 267, 1834-1837.[Abstract/Free Full Text]

Liao, G. and Gundersen, G. G (1998). Kinesin is a candidate for cross-bridging microtubules and intermediate filaments. J. Biol. Chem 273, 9797-9803.[Abstract/Free Full Text]

Lippincott-Schwartz, J (1998). Cytoskeletal proteins and Golgi dynamics. Curr. Opin. Cell Biol 10, 52-59.[Medline]

Lippincott-Schwartz, J., Cole, N. B., Marotta, A., Conrad, P. A. and Bloom, G. S (1995). Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic. J. Cell Biol 128, 293-306.[Abstract/Free Full Text]

Mandelkow, E. and Mandelkow, E. M (1995). Microtubules and microtubule-associated proteins. Curr. Opin. Cell Biol 7, 72-81.[Medline]

Matus, A (1994). Stiff microtubules and neuronal morphology. Trends Neurosci 17, 19-22.[Medline]

Morris, R. L. and Hollenbeck, P. J (1993). The regulation of bidirectional mitochondrial transport is coordinated with axonal outgrowth. J. Cell Sci 104, 917-927.[Abstract]

Morris, R. L. and Hollenbeck, P. J (1995). Axonal transport of mitochondria along microtubules and F-actin in living vertebrate neurons. J. Cell Biol 131, 1315-1326.[Abstract/Free Full Text]

Olson, K. R., McIntosh, J. R. and Olmsted, J. B (1995). Analysis of MAP 4 function in living cells using green fluorescent protein (GFP) chimeras. J. Cell Biol 130, 639-650.[Abstract/Free Full Text]

Paschal, B. M., Obar, R. A. and Vallee, R. B (1989). Interaction of brain cytoplasmic dynein and MAP2 with a common sequence at the C-terminus of tubulin. Nature 342, 569-572.[Medline]

Prahlad V., Yoon M., Moir R. D., Vale R. D. and Goldman R. D (1998). Rapid movements of vimentin on microtubule tracks: kinesin-dependent assembly of intermediate filament networks. J. Cell Biol 143, 159-170.[Abstract/Free Full Text]

Presley, J. F., Cole, N. B., Schroer, T. A., Hirschberg, K., Zaal, K. J. and Lippincott-Schwartz, J (1997). ER-to Golgi transport visualized in living cells. Nature 389, 81-85.[Medline]

Preuss, U., D\232ring, F., Illenberger, S. and Mandelkow, E.-M (1995). Cell-cycle dependent phosphorylation and microtubule-binding of tau-protein stably transfected into chinese-hamster ovary cells. Mol. Biol. Cell 6, 1397-1410.[Abstract]

Preuss, U., Biernat, J., Mandelkow, E.-M. and Mandelkow, E (1997). The \324jaws' model of tau-microtubule interaction examined in CHO cells. J. Cell Sci 110, 789-800.[Abstract]

Ratner, N., Bloom, G. and Brady, S (1998). A role for cyclin-dependent kinase(s) in the modulation of fast anterograde axonal transport: effects defined by olomoucine and the APC tumor suppressor protein. J. Neurosci 18, 7717-7726.[Abstract/Free Full Text]

Rodionov, V. I., Gyoeva, F. K., Tanaka, E., Bershadsky, A. D., Vasiliev, J. M. and Gelfand, V. I (1993). Microtubule-dependent control of cell-shape and pseudopodial activity is inhibited by the antibody to kinesin motor domain. J. Cell Biol 123, 1811-1820.[Abstract/Free Full Text]

Rothman, J. E (1994). Mechanism of intracellular protein transport. Nature 372, 55-63.[Medline]

Sato-Harada, R., Okabe, S., Umeyama, T., Kanai, Y. and Hirokawa, N (1996). Microtubule-associated proteins regulate microtubule function as the track for intracellular membrane organelle transports. Cell Struct. Funct 21, 283-295.[Medline]

Scales, S. J., Pepperkok, R. and Kreis, T. E (1997). Visualization of ER-to-Golgi transport in living cells reveals a sequential mode of action for COPII and COPI. Cell 90, 1137-1148.[Medline]

Tanaka, Y., Kanai, Y., Okada, Y., Nonaka, S., Takeda, S., Harada, A. and Hirokawa, N (1998). Targeted disruption of mouse conventional kinesin heavy chain, kif5B, results in abnormal perinuclear clustering of mitochondria. Cell 93, 1147-1158.[Medline]

Urbani, L. and Simoni, R. D (1990). Cholesterol and vesicular stomatitis virus G protein take separate routes from the endoplasmic reticulum to the plasma membrane. J. Biol. Chem 265, 1919-1923.[Abstract/Free Full Text]

Vallee, R. B. and Sheetz, M. P (1996). Targeting of motor proteins. Science 271, 1539-1544.[Abstract]

von Massow, A., Mandelkow, E.-M. and Mandelkow, E (1989). Interactionbetween kinesin, microtubules, and microtubule-associated protein 2. Cell Motil. Cytoskel 14, 562-571.[Medline]

Wacker, I., Kaether, C., Kromer, A., Migala, A., Almers, W. and Gerdes, H. H (1997). Microtubule-dependent transport of secretory vesicles visualized in real time with a GFP-tagged secretory protein. J. Cell Sci 110, 1453-1463.[Abstract]

Wang Z., Khan S. and Sheetz M. P (1995). Single cytoplasmic dynein molecule movements: characterization and comparison with kinesin. Biophys. J 69, 2011-2023.[Abstract/Free Full Text]

Waterman-Storer, C. and Salmon, E. D (1997). Microtubule dynamics: treadmilling comes around again. Curr. Biol 7, 369-372.

Weisshaar, B., Doll, T. and Matus, A (1992). Reorganization of the microtubular cytoskeleton by embryonic microtubule-associated protein 2 (MAP2c). Development 116, 1151-1161.[Abstract]

West, R. R., Tenbarge, K. M. and Olmsted, J. B (1991). A model for microtubule-associated protein 4 structure. Domains defined by comparisons of human, mouse, and bovine sequences. J. Biol. Chem 266, 21886-21896.[Abstract/Free Full Text]

Wiemer, E., Wenzel, T., Deerinck, T. J., Ellisman, M. H. and Subramani, S (1997). Visualization of the peroxisomal compartment in living mammalian cells: dynamic behavior and association with microtubules. J. Cell Biol 136, 71-80.[Abstract/Free Full Text]

Yoon M., Moir R. D., Prahlad V. and Goldman R. D (1998). Motile properties of vimentin intermediate filament networks in living cells. J. Cell Biol 143, 147-157.[Abstract/Free Full Text]

This article has been cited by other articles:

R. Dixit, J. L. Ross, Y. E. Goldman, and E. L. F. Holzbaur
Differential Regulation of Dynein and Kinesin Motor Proteins by Tau
Science, February 22, 2008; 319(5866): 1086 - 1089.
[Abstract] [Full Text] [PDF]

S. Konzack, E. Thies, A. Marx, E.-M. Mandelkow, and E. Mandelkow
Swimming against the Tide: Mobility of the Microtubule-Associated Protein Tau in Neurons
J. Neurosci., September 12, 2007; 27(37): 9916 - 9927.
[Abstract] [Full Text] [PDF]

C. Goldsbury, E. Thies, S. Konzack, and E.-M. Mandelkow
Quantification of Amyloid Precursor Protein and Tau for the Study of Axonal Traffic Pathways
J. Neurosci., March 28, 2007; 27(13): 3357 - 3363.
[Full Text] [PDF]

M. Vershinin, B. C. Carter, D. S. Razafsky, S. J. King, and S. P. Gross
Multiple-motor based transport and its regulation by Tau
PNAS, January 2, 2007; 104(1): 87 - 92.
[Abstract] [Full Text] [PDF]

J. Ashby, E. Boutant, M. Seemanpillai, A. Sambade, C. Ritzenthaler, and M. Heinlein
Tobacco mosaic virus movement protein functions as a structural microtubule-associated protein.
J. Virol., September 1, 2006; 80(17): 8329 - 8344.
[Abstract] [Full Text] [PDF]

A.-T. Dinh, C. Pangarkar, T. Theofanous, and S. Mitragotri
Theory of Spatial Patterns of Intracellular Organelles
Biophys. J., May 15, 2006; 90(10): L67 - L69.
[Abstract] [Full Text] [PDF]

V. S. Subramanian, J. S. Marchant, and H. M. Said
Targeting and Trafficking of the Human Thiamine Transporter-2 in Epithelial Cells
J. Biol. Chem., February 24, 2006; 281(8): 5233 - 5245.
[Abstract] [Full Text] [PDF]

A. A. Minin, A. V. Kulik, F. K. Gyoeva, Y. Li, G. Goshima, and V. I. Gelfand
Regulation of mitochondria distribution by RhoA and formins
J. Cell Sci., February 15, 2006; 119(4): 659 - 670.
[Abstract] [Full Text] [PDF]

S. Klumpp and R. Lipowsky
Cooperative cargo transport by several molecular motors
PNAS, November 29, 2005; 102(48): 17284 - 17289.
[Abstract] [Full Text] [PDF]

M. A. Utton, W. J. Noble, J. E. Hill, B. H. Anderton, and D. P. Hanger
Molecular motors implicated in the axonal transport of tau and {alpha}-synuclein
J. Cell Sci., October 15, 2005; 118(20): 4645 - 4654.
[Abstract] [Full Text] [PDF]

M. Higuchi, B. Zhang, M. S. Forman, Y. Yoshiyama, J. Q. Trojanowski, and V. M.-Y. Lee
Axonal Degeneration Induced by Targeted Expression of Mutant Human Tau in Oligodendrocytes of Transgenic Mice That Model Glial Tauopathies
J. Neurosci., October 12, 2005; 25(41): 9434 - 9443.
[Abstract] [Full Text] [PDF]

B. E. Kremer, T. Haystead, and I. G. Macara
Mammalian Septins Regulate Microtubule Stability through Interaction with the Microtubule-binding Protein MAP4
Mol. Biol. Cell, October 1, 2005; 16(10): 4648 - 4659.
[Abstract] [Full Text] [PDF]

F. Darios, M.-P. Muriel, M. E. Khondiker, A. Brice, and M. Ruberg
Neurotoxic Calcium Transfer from Endoplasmic Reticulum to Mitochondria Is Regulated by Cyclin-Dependent Kinase 5-Dependent Phosphorylation of Tau
J. Neurosci., April 20, 2005; 25(16): 4159 - 4168.
[Abstract] [Full Text] [PDF]

C. Vedrenne, D. R. Klopfenstein, and H.-P. Hauri
Phosphorylation Controls CLIMP-63-mediated Anchoring of the Endoplasmic Reticulum to Microtubules
Mol. Biol. Cell, April 1, 2005; 16(4): 1928 - 1937.
[Abstract] [Full Text] [PDF]

A. Samsonov, J.-Z. Yu, M. Rasenick, and S. V. Popov
Tau interaction with microtubules in vivo
J. Cell Sci., December 1, 2004; 117(25): 6129 - 6141.
[Abstract] [Full Text] [PDF]

E.-M. Mandelkow, E. Thies, B. Trinczek, J. Biernat, and E. Mandelkow
MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons
J. Cell Biol., October 11, 2004; 167(1): 99 - 110.
[Abstract] [Full Text] [PDF]

W. K.-H. Chan, A. Dickerson, D. Ortiz, A. F. Pimenta, C. M. Moran, J. Motil, S. J. Snyder, K. Malik, H. C. Pant, and T. B. Shea
Mitogen-activated protein kinase regulates neurofilament axonal transport
J. Cell Sci., September 15, 2004; 117(20): 4629 - 4642.
[Abstract] [Full Text] [PDF]

L. Liao, D. Cheng, J. Wang, D. M. Duong, T. G. Losik, M. Gearing, H. D. Rees, J. J. Lah, A. I. Levey, and J. Peng
Proteomic Characterization of Postmortem Amyloid Plaques Isolated by Laser Capture Microdissection
J. Biol. Chem., August 27, 2004; 279(35): 37061 - 37068.
[Abstract] [Full Text] [PDF]

C. Li, Y. Sasaki, K. Takei, H. Yamamoto, M. Shouji, Y. Sugiyama, T. Kawakami, F. Nakamura, T. Yagi, T. Ohshima, et al.
Correlation between Semaphorin3A-Induced Facilitation of Axonal Transport and Local Activation of a Translation Initiation Factor Eukaryotic Translation Initiation Factor 4E
J. Neurosci., July 7, 2004; 24(27): 6161 - 6170.
[Abstract] [Full Text] [PDF]

V. S. Subramanian, J. S. Marchant, M. J. Boulware, and H. M. Said
A C-terminal Region Dictates the Apical Plasma Membrane Targeting of the Human Sodium-dependent Vitamin C Transporter-1 in Polarized Epithelia
J. Biol. Chem., June 25, 2004; 279(26): 27719 - 27728.
[Abstract] [Full Text] [PDF]

K. E. Miller and M. P. Sheetz
Axonal mitochondrial transport and potential are correlated
J. Cell Sci., June 1, 2004; 117(13): 2791 - 2804.
[Abstract] [Full Text] [PDF]

J. M. Bunker, L. Wilson, M. A. Jordan, and S. C. Feinstein
Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration
Mol. Biol. Cell, June 1, 2004; 15(6): 2720 - 2728.
[Abstract] [Full Text] [PDF]

Y. Tatebayashi, N. Haque, Y.-C. Tung, K. Iqbal, and I. Grundke-Iqbal
Role of tau phosphorylation by glycogen synthase kinase-3{beta} in the regulation of organelle transport
J. Cell Sci., May 1, 2004; 117(9): 1653 - 1663.
[Abstract] [Full Text] [PDF]

B. T. Helfand, L. Chang, and R. D. Goldman
Intermediate filaments are dynamic and motile elements of cellular architecture
J. Cell Sci., January 15, 2004; 117(2): 133 - 141.
[Abstract] [Full Text] [PDF]

Y. Yoshiyama, B. Zhang, J. Bruce, J. Q. Trojanowski, and V. M.-Y. Lee
Reduction of Detyrosinated Microtubules and Golgi Fragmentation Are Linked to Tau-Induced Degeneration in Astrocytes
J. Neurosci., November 19, 2003; 23(33): 10662 - 10671.
[Abstract] [Full Text] [PDF]

E. Schofield, C. Kersaitis, C. E. Shepherd, J. J. Kril, and G. M. Halliday
Severity of gliosis in Pick's disease and frontotemporal lobar degeneration: tau-positive glia differentiate these disorders
Brain, April 1, 2003; 126(4): 827 - 840.
[Abstract] [Full Text] [PDF]

J. Schmoranzer and S. M. Simon
Role of Microtubules in Fusion of Post-Golgi Vesicles to the Plasma Membrane
Mol. Biol. Cell, April 1, 2003; 14(4): 1558 - 1569.
[Abstract] [Full Text] [PDF]

V. S. Subramanian, J. S. Marchant, I. Parker, and H. M. Said
Cell Biology of the Human Thiamine Transporter-1 (hTHTR1). INTRACELLULAR TRAFFICKING AND MEMBRANE TARGETING MECHANISMS
J. Biol. Chem., January 31, 2003; 278(6): 3976 - 3984.
[Abstract] [Full Text] [PDF]

J.-H. Cho and G. V. W. Johnson
Glycogen Synthase Kinase 3beta Phosphorylates Tau at Both Primed and Unprimed Sites. DIFFERENTIAL IMPACT ON MICROTUBULE BINDING
J. Biol. Chem., January 3, 2003; 278(1): 187 - 193.
[Abstract] [Full Text] [PDF]

G. Cheng, Y. Iijima, Y. Ishibashi, D. Kuppuswamy, and G. Cooper IV
Inhibition of G protein-coupled receptor trafficking in neuroblastoma cells by MAP 4 decoration of microtubules
Am J Physiol Heart Circ Physiol, December 1, 2002; 283(6): H2379 - H2388.
[Abstract] [Full Text] [PDF]

J. S. Marchant, V. S. Subramanian, I. Parker, and H. M. Said
Intracellular Trafficking and Membrane Targeting Mechanisms of the Human Reduced Folate Carrier in Mammalian Epithelial Cells
J. Biol. Chem., August 30, 2002; 277(36): 33325 - 33333.
[Abstract] [Full Text] [PDF]

M. A. Utton, J. Connell, A. A. Asuni, M. van Slegtenhorst, M. Hutton, R. de Silva, A. J. Lees, C. C. J. Miller, and B. H. Anderton
The Slow Axonal Transport of the Microtubule-Associated Protein Tau and the Transport Rates of Different Isoforms and Mutants in Cultured Neurons
J. Neurosci., August 1, 2002; 22(15): 6394 - 6400.
[Abstract] [Full Text] [PDF]

J. Al-Bassam, R. S. Ozer, D. Safer, S. Halpain, and R. A. Milligan
MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments
J. Cell Biol., June 24, 2002; 157(7): 1187 - 1196.
[Abstract] [Full Text] [PDF]

M. Rapoport, H. N. Dawson, L. I. Binder, M. P. Vitek, and A. Ferreira
Tau is essential to beta -amyloid-induced neurotoxicity
PNAS, April 10, 2002; (2002) 92136199.
[Abstract] [Full Text] [PDF]

K. Stamer, R. Vogel, E. Thies, E. Mandelkow, and E.-M. Mandelkow
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
J. Cell Biol., March 18, 2002; 156(6): 1051 - 1063.
[Abstract] [Full Text] [PDF]

M. Hollinshead, G. Rodger, H. Van Eijl, M. Law, R. Hollinshead, D. J.T. Vaux, and G. L. Smith
Vaccinia virus utilizes microtubules for movement to the cell surface
J. Cell Biol., July 23, 2001; 154(2): 389 - 402.
[Abstract] [Full Text] [PDF]

A. I. Marcus, R. C. Moore, and R. J. Cyr
The Role of Microtubules in Guard Cell Function
Plant Physiology, January 1, 2001; 125(1): 387 - 395.
[Abstract] [Full Text]

P. Rizzu, M. Joosse, R. Ravid, A. Hoogeveen, W. Kamphorst, J. C. van Swieten, R. Willemsen, and P. Heutink
Mutation-dependent aggregation of tau protein and its selective depletion from the soluble fraction in brain of P301L FTDP-17 patients
Hum. Mol. Genet., December 1, 2000; 9(20): 3075 - 3082.
[Abstract] [Full Text] [PDF]

J. GOTZ, R. BARMETTLER, A. FERRARI, M. GOEDERT, A. PROBST, and R. M. NITSCH
In Vivo Analysis of Wild-type and FTDP-17 Tau Transgenic Mice
Ann. N.Y. Acad. Sci., December 1, 2000; 920(1): 126 - 133.
[Abstract] [Full Text] [PDF]

Y.-H. Chou and R. D. Goldman
Intermediate Filaments on the Move
J. Cell Biol., August 7, 2000; 150(3): F101 - F106.
[Abstract] [Full Text] [PDF]

D. Peretti, L. Peris, S. Rosso, S. Quiroga, and A. Caceres
Evidence for the Involvement of KIF4 in the Anterograde Transport of L1-containing Vesicles
J. Cell Biol., April 3, 2000; 149(1): 141 - 152.
[Abstract] [Full Text] [PDF]

M. P. Koonce and I. Tikhonenko
Functional Elements within the Dynein Microtubule-binding Domain
Mol. Biol. Cell, February 1, 2000; 11(2): 523 - 529.
[Abstract] [Full Text]

K. Spittaels, C. Van den Haute, J. Van Dorpe, H. Geerts, M. Mercken, K. Bruynseels, R. Lasrado, K. Vandezande, I. Laenen, T. Boon, et al.
Glycogen Synthase Kinase-3beta Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice
J. Biol. Chem., December 22, 2000; 275(52): 41340 - 41349.
[Abstract] [Full Text] [PDF]

J. Gotz, F. Chen, R. Barmettler, and R. M. Nitsch
Tau Filament Formation in Transgenic Mice Expressing P301L Tau
J. Biol. Chem., January 5, 2001; 276(1): 529 - 534.
[Abstract] [Full Text] [PDF]

M. Emoto, S. E. Langille, and M. P. Czech
A Role for Kinesin in Insulin-stimulated GLUT4 Glucose Transporter Translocation in 3T3-L1 Adipocytes
J. Biol. Chem., March 30, 2001; 276(14): 10677 - 10682.
[Abstract] [Full Text] [PDF]

M. Rapoport, H. N. Dawson, L. I. Binder, M. P. Vitek, and A. Ferreira
Tau is essential to beta -amyloid-induced neurotoxicity
PNAS, April 30, 2002; 99(9): 6364 - 6369.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Trinczek, B.

<

				S. Konzack, E. Thies, A. Marx, E.-M. Mandelkow, and E. Mandelkow Swimming against the Tide: Mobility of the Microtubule-Associated Protein Tau in Neurons J. Neurosci., September 12, 2007; 27(37): 9916 - 9927. [Abstract] [Full Text] [PDF]

				C. Goldsbury, E. Thies, S. Konzack, and E.-M. Mandelkow Quantification of Amyloid Precursor Protein and Tau for the Study of Axonal Traffic Pathways J. Neurosci., March 28, 2007; 27(13): 3357 - 3363. [Full Text] [PDF]

				M. Vershinin, B. C. Carter, D. S. Razafsky, S. J. King, and S. P. Gross Multiple-motor based transport and its regulation by Tau PNAS, January 2, 2007; 104(1): 87 - 92. [Abstract] [Full Text] [PDF]

				J. Ashby, E. Boutant, M. Seemanpillai, A. Sambade, C. Ritzenthaler, and M. Heinlein Tobacco mosaic virus movement protein functions as a structural microtubule-associated protein. J. Virol., September 1, 2006; 80(17): 8329 - 8344. [Abstract] [Full Text] [PDF]

				A.-T. Dinh, C. Pangarkar, T. Theofanous, and S. Mitragotri Theory of Spatial Patterns of Intracellular Organelles Biophys. J., May 15, 2006; 90(10): L67 - L69. [Abstract] [Full Text] [PDF]

				V. S. Subramanian, J. S. Marchant, and H. M. Said Targeting and Trafficking of the Human Thiamine Transporter-2 in Epithelial Cells J. Biol. Chem., February 24, 2006; 281(8): 5233 - 5245. [Abstract] [Full Text] [PDF]

				A. A. Minin, A. V. Kulik, F. K. Gyoeva, Y. Li, G. Goshima, and V. I. Gelfand Regulation of mitochondria distribution by RhoA and formins J. Cell Sci., February 15, 2006; 119(4): 659 - 670. [Abstract] [Full Text] [PDF]

				S. Klumpp and R. Lipowsky Cooperative cargo transport by several molecular motors PNAS, November 29, 2005; 102(48): 17284 - 17289. [Abstract] [Full Text] [PDF]

				M. A. Utton, W. J. Noble, J. E. Hill, B. H. Anderton, and D. P. Hanger Molecular motors implicated in the axonal transport of tau and {alpha}-synuclein J. Cell Sci., October 15, 2005; 118(20): 4645 - 4654. [Abstract] [Full Text] [PDF]

				M. Higuchi, B. Zhang, M. S. Forman, Y. Yoshiyama, J. Q. Trojanowski, and V. M.-Y. Lee Axonal Degeneration Induced by Targeted Expression of Mutant Human Tau in Oligodendrocytes of Transgenic Mice That Model Glial Tauopathies J. Neurosci., October 12, 2005; 25(41): 9434 - 9443. [Abstract] [Full Text] [PDF]

				B. E. Kremer, T. Haystead, and I. G. Macara Mammalian Septins Regulate Microtubule Stability through Interaction with the Microtubule-binding Protein MAP4 Mol. Biol. Cell, October 1, 2005; 16(10): 4648 - 4659. [Abstract] [Full Text] [PDF]

				F. Darios, M.-P. Muriel, M. E. Khondiker, A. Brice, and M. Ruberg Neurotoxic Calcium Transfer from Endoplasmic Reticulum to Mitochondria Is Regulated by Cyclin-Dependent Kinase 5-Dependent Phosphorylation of Tau J. Neurosci., April 20, 2005; 25(16): 4159 - 4168. [Abstract] [Full Text] [PDF]

				C. Vedrenne, D. R. Klopfenstein, and H.-P. Hauri Phosphorylation Controls CLIMP-63-mediated Anchoring of the Endoplasmic Reticulum to Microtubules Mol. Biol. Cell, April 1, 2005; 16(4): 1928 - 1937. [Abstract] [Full Text] [PDF]

				A. Samsonov, J.-Z. Yu, M. Rasenick, and S. V. Popov Tau interaction with microtubules in vivo J. Cell Sci., December 1, 2004; 117(25): 6129 - 6141. [Abstract] [Full Text] [PDF]

				E.-M. Mandelkow, E. Thies, B. Trinczek, J. Biernat, and E. Mandelkow MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons J. Cell Biol., October 11, 2004; 167(1): 99 - 110. [Abstract] [Full Text] [PDF]

				W. K.-H. Chan, A. Dickerson, D. Ortiz, A. F. Pimenta, C. M. Moran, J. Motil, S. J. Snyder, K. Malik, H. C. Pant, and T. B. Shea Mitogen-activated protein kinase regulates neurofilament axonal transport J. Cell Sci., September 15, 2004; 117(20): 4629 - 4642. [Abstract] [Full Text] [PDF]

				L. Liao, D. Cheng, J. Wang, D. M. Duong, T. G. Losik, M. Gearing, H. D. Rees, J. J. Lah, A. I. Levey, and J. Peng Proteomic Characterization of Postmortem Amyloid Plaques Isolated by Laser Capture Microdissection J. Biol. Chem., August 27, 2004; 279(35): 37061 - 37068. [Abstract] [Full Text] [PDF]

				C. Li, Y. Sasaki, K. Takei, H. Yamamoto, M. Shouji, Y. Sugiyama, T. Kawakami, F. Nakamura, T. Yagi, T. Ohshima, et al. Correlation between Semaphorin3A-Induced Facilitation of Axonal Transport and Local Activation of a Translation Initiation Factor Eukaryotic Translation Initiation Factor 4E J. Neurosci., July 7, 2004; 24(27): 6161 - 6170. [Abstract] [Full Text] [PDF]

				V. S. Subramanian, J. S. Marchant, M. J. Boulware, and H. M. Said A C-terminal Region Dictates the Apical Plasma Membrane Targeting of the Human Sodium-dependent Vitamin C Transporter-1 in Polarized Epithelia J. Biol. Chem., June 25, 2004; 279(26): 27719 - 27728. [Abstract] [Full Text] [PDF]

				K. E. Miller and M. P. Sheetz Axonal mitochondrial transport and potential are correlated J. Cell Sci., June 1, 2004; 117(13): 2791 - 2804. [Abstract] [Full Text] [PDF]

				J. M. Bunker, L. Wilson, M. A. Jordan, and S. C. Feinstein Modulation of Microtubule Dynamics by Tau in Living Cells: Implications for Development and Neurodegeneration Mol. Biol. Cell, June 1, 2004; 15(6): 2720 - 2728. [Abstract] [Full Text] [PDF]

				Y. Tatebayashi, N. Haque, Y.-C. Tung, K. Iqbal, and I. Grundke-Iqbal Role of tau phosphorylation by glycogen synthase kinase-3{beta} in the regulation of organelle transport J. Cell Sci., May 1, 2004; 117(9): 1653 - 1663. [Abstract] [Full Text] [PDF]

				B. T. Helfand, L. Chang, and R. D. Goldman Intermediate filaments are dynamic and motile elements of cellular architecture J. Cell Sci., January 15, 2004; 117(2): 133 - 141. [Abstract] [Full Text] [PDF]

				Y. Yoshiyama, B. Zhang, J. Bruce, J. Q. Trojanowski, and V. M.-Y. Lee Reduction of Detyrosinated Microtubules and Golgi Fragmentation Are Linked to Tau-Induced Degeneration in Astrocytes J. Neurosci., November 19, 2003; 23(33): 10662 - 10671. [Abstract] [Full Text] [PDF]

				E. Schofield, C. Kersaitis, C. E. Shepherd, J. J. Kril, and G. M. Halliday Severity of gliosis in Pick's disease and frontotemporal lobar degeneration: tau-positive glia differentiate these disorders Brain, April 1, 2003; 126(4): 827 - 840. [Abstract] [Full Text] [PDF]

				J. Schmoranzer and S. M. Simon Role of Microtubules in Fusion of Post-Golgi Vesicles to the Plasma Membrane Mol. Biol. Cell, April 1, 2003; 14(4): 1558 - 1569. [Abstract] [Full Text] [PDF]

				V. S. Subramanian, J. S. Marchant, I. Parker, and H. M. Said Cell Biology of the Human Thiamine Transporter-1 (hTHTR1). INTRACELLULAR TRAFFICKING AND MEMBRANE TARGETING MECHANISMS J. Biol. Chem., January 31, 2003; 278(6): 3976 - 3984. [Abstract] [Full Text] [PDF]

				J.-H. Cho and G. V. W. Johnson Glycogen Synthase Kinase 3beta Phosphorylates Tau at Both Primed and Unprimed Sites. DIFFERENTIAL IMPACT ON MICROTUBULE BINDING J. Biol. Chem., January 3, 2003; 278(1): 187 - 193. [Abstract] [Full Text] [PDF]

				G. Cheng, Y. Iijima, Y. Ishibashi, D. Kuppuswamy, and G. Cooper IV Inhibition of G protein-coupled receptor trafficking in neuroblastoma cells by MAP 4 decoration of microtubules Am J Physiol Heart Circ Physiol, December 1, 2002; 283(6): H2379 - H2388. [Abstract] [Full Text] [PDF]

				J. S. Marchant, V. S. Subramanian, I. Parker, and H. M. Said Intracellular Trafficking and Membrane Targeting Mechanisms of the Human Reduced Folate Carrier in Mammalian Epithelial Cells J. Biol. Chem., August 30, 2002; 277(36): 33325 - 33333. [Abstract] [Full Text] [PDF]