Mechanism of extracellular domain-deleted dominant negative cadherins

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Amagai, M., Fujimori, T., Masunaga, T., Shimizu, H., Nishikawa, T., Shimizu, N., Takeichi, M. and Hashimoto, T (1995). Delayed assembly of desmosomes in keratinocytes with disrupted classic-cadherin-mediated cell adhesion by a dominant negative mutant. J. Invest. Dermatol 104, 27-32.[Medline]

Aronheim, A., Engelberg, D., Li, N., al-Alawi, N., Schlessinger, J. and Karin, M (1994). Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway. Cell 78, 949-961.[Medline]

Butz, S. and Kemler, R (1994). Distinct cadherin-catenin complexes in Ca2+-dependent cell-cell adhesion. FEBS Lett 355, 195-200.[Medline]

Clarke, S (1992). Protein isoprenylation and methylation at carboxyl-terminal cysteine residues. Annu. Rev. Biochem 61, 355-386.[Medline]

Choi, Y. S. and Gumbiner, B (1989). Expression of cell adhesion molecule E-cadherin in Xenopus embryos begins at gastrulation and predominates in the ectoderm. J. Cell Biol 108, 2449-2458.[Abstract/Free Full Text]

Falcone, D. and Andrews, D. W (1991). Both the 5' untranslated region and the sequences surrounding the start site contribute to efficient initiation of translation in vitro. Mol. Cell Biol 11, 2656-2664.[Abstract/Free Full Text]

Fujimori, T. and Takeichi, M (1993). Disruption of epithelial cell-celladhesion by exogenous expression of a mutated nonfunctional N-cadherin. Mol. Biol. Cell 4, 37-47.[Abstract]

Gordon, J. I., Duronio, R. J. Rudnick, D. A., Adams, S. P. and Gokel, G. W (1991). Protein N-myristoylation. J. Biol. Chem 266, 8647-8650.[Free Full Text]

Hancock, J. F., Paterson, H. and Marshall, C. J (1990). A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane. Cell 63, 133-139.[Medline]

Hazan, R. B., Kang, L., Roe, S., Borgen, P. I. and Rimm, D. L (1997). Vinculin is associated with the E-cadherin adhesion complex. J. Biol. Chem 272, 32448-32453.[Abstract/Free Full Text]

Hermiston, M. L. and Gordon, J. I (1995). In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death. J. Cell Biol 129, 489-506.[Abstract/Free Full Text]

Hermiston, M. L. and Gordon, J. I (1995). Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 270, 1203-1207.[Abstract/Free Full Text]

Hinck, L., N\212thke, I. S., Papkoff, J. and Nelson, W. J (1994). Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. J. Cell Biol 125, 1327-1340.[Abstract/Free Full Text]

Hobbs, M. V., Weigle, W. O., Noonan, D. J., Torbett, B. E., McEvilly, R. J., Koch, R. J., Cardenas, G. J. and Ernst, D. N (1993). Patterns of cytokine gene expression by CD4+T cells from young and old mice. J. Immunol 150, 3602-3614.[Abstract]

Huber, O., Krohn, M. and Kemler, R (1997). A specific domain in-catenin mediates binding to -catenin or plakoglobin. J. Cell Sci 110, 1759-1765.[Abstract]

Islam, S., Carey, T. E., Wolf, G. T., Wheelock, M. J. and Johnson, K. R (1996). Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion. J. Cell Biol 135, 1643-1654.[Abstract/Free Full Text]

Johnson, K. R., Lewis, J. E., Li, D., Wahl, J., Soler, A. P., Knudsen, K. A. and Wheelock, M. J (1993). P-and E-cadherin are in separate complexes in cells expressing both cadherins. Exp. Cell Res 207, 252-260.[Medline]

Kintner, C (1992). Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell 69, 225-236.[Medline]

Knudsen, K. A., Soler, A. P., Johnson, K. R. and Wheelock, M. J (1995). Interaction of-actinin with the N-cadherin/catenin cell-cell adhesion complex via -catenin. J. Cell Biol 130, 67-77.[Abstract/Free Full Text]

Laemmli, U. K (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.[Medline]

Levi, G., Gumbiner, B. M. and Thiery, J.-P (1991). The distribution of E-cadherin during Xenopus leavis development. Development 111, 158-169.

Levine, E., Lee, C. H., Kintner, C. and Gumbiner, B. M (1994). Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant. Development 120, 901-909.[Abstract]

Lewis, J. E., Jensen, P. J. and Wheelock, M. J (1994). Cadherin function is required for human keratinocytes to assemble desmosomes and stratify in response to calcium. J. Invest. Dermatol 102, 870-877.[Medline]

McNeill, H., Ozawa, M., Kemler, R. and Nelson, W. J (1990). Novel function of cell adhesion molecule uvomorulin as an inducer of cell surface polarity. Cell 62, 309-316.[Medline]

Nagar B., Overduin, M., Ikura, M. and Rini, J. M (1996). Structural basis of calcium-induced E-cadherin rigidification and dimerization. Nature 380, 360-364.[Medline]

N\212thke, I. S., Hinck, L., Swedlow, J. R., Papkoff, J. and Nelson, W. J (1994). Defining interactions and distributions of cadherin and catenin complexes in polarized epithelial cells. J. Cell Biol 125, 1341-1352.[Abstract/Free Full Text]

Nieset, J. E., Redfield, A. R., Jin, F., Knudsen, K. A., Johnson, K. R. and Wheelock, M. J (1997). Characterization of the interactions of-catenin with -actinin and-catenin/plakoglobin. J. Cell Sci 110, 1013-1022.[Abstract]

Ozawa, M. and Kemler, R (1998). The membrane-proximal region of the E-cadherin cytoplasmic domain prevents dimerization and negatively regulates adhesion activity. J. Cell Biol 142, 1605-1613.[Abstract/Free Full Text]

Resh, M. D (1994). Myristylation and palmitylation of Src family members: the fats of the matter. Cell 76, 411-413.[Medline]

Rimm, D. L., Koslov, E. R., Kebriaei, P., Cianci, C. D. and Morrow, J. S (1995). 1(E)-catenin is an actin-binding and-bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc. Nat. Acad. Sci. USA 92, 8813-8817.[Abstract/Free Full Text]

Rochford R., Hobbs, M. V., Garnier, J. L., Cooper, N. R. and Cannon, M. J (1993). Plasmacytoid differentiation of Epstein-Barr virus-transformed B cells in vivo is associated with reduced expression of viral latent genes. Proc. Nat. Acad. Sci. USA 90, 352-356.[Abstract/Free Full Text]

Sacco, P. A., McGranahan, T. M., Wheelock, M. J. and Johnson, K. R (1995). Identification of plakoglobin domains required for association with N-cadherin and -catenin. J. Biol. Chem 270, 20201-20206.[Abstract/Free Full Text]

Stappert, J. and Kemler, R (1994). A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated. Cell Adhes. Commun 2, 319-327.[Medline]

Steinberg, M. S. and Takeichi, M (1994). Experimental specification of cell sorting, tissue spreading, and specific spatial patterning by quantitative differences in cadherin expression. Proc. Nat. Acad. Sci USA 91, 206-209.[Abstract/Free Full Text]

Takeichi, M (1993). Cadherins in cancer: implications for invasion and metastasis. Curr. Opin. Cell Biol 5, 806-811.[Medline]

Takeichi, M (1995). Morphogenetic roles of classic cadherins. Curr. Opin. Cell Biol 7, 619-627.[Medline]

Towler, D. A., Gordon, J. I., Adams, S. P. and Glaser, L (1988). The biology and enzymology of eukaryotic protein acylation. Annu. Rev. Biochem 57, 69-99.[Medline]

Watabe-Uchida, M., Uchida, N., Imamura, Y., Nagafuchi, A., Fujimoto, K., Uemura, T., Vermeulen, S., van Roy, F., Adamson, E. D. and Takeichi, M (1998). -catenin-vinculin interaction functions to organizethe apical junctional complex in epithelial cells. J. Cell Biol 142, 847-857.[Abstract/Free Full Text]

Weiss, E. E., Kroemker, M., Rudiger, A.-H., Jockusch, B. M. and Rudiger, M (1998). Vinculin is part of the cadherin-catenin junctional complex: complex formation between-catenin and vinculin. J. Cell Biol 141, 755-764.[Abstract/Free Full Text]

Wheelock, M. J., Buck, C. A., Bechtol, K. B. and Damsky, C. H (1987). Soluble 80-kD fragment of cell-CAM 120/80 disrupts cell-cell adhesion. J. Cell. Biochem 34, 187-202.[Medline]

Yap, A. S., Niessen, C. M. and Gumbiner, B. M (1998). The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. J. Cell Biol 141, 779-789.[Abstract/Free Full Text]

Zhu, A. J. and Watt, F. M (1996). Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes. J. Cell Sci 109, 3013-3023.[Abstract]

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				C. H. M. Castro, C. S. Shin, J. P. Stains, S.-L. Cheng, S. Sheikh, G. Mbalaviele, V. L. Szejnfeld, and R. Civitelli Targeted expression of a dominant-negative N-cadherin in vivo delays peak bone mass and increases adipogenesis J. Cell Sci., June 1, 2004; 117(13): 2853 - 2864. [Abstract] [Full Text] [PDF]

				S. Iyer, D. M. Ferreri, N. C. DeCocco, F. L. Minnear, and P. A. Vincent VE-cadherin-p120 interaction is required for maintenance of endothelial barrier function Am J Physiol Lung Cell Mol Physiol, June 1, 2004; 286(6): L1143 - L1153. [Abstract] [Full Text] [PDF]

				P. A. Vincent, K. Xiao, K. M. Buckley, and A. P. Kowalczyk VE-cadherin: adhesion at arm's length Am J Physiol Cell Physiol, May 1, 2004; 286(5): C987 - C997. [Abstract] [Full Text] [PDF]

				M. Guo, M. H. Wu, H. J. Granger, and S. Y. Yuan Transference of recombinant VE-cadherin cytoplasmic domain alters endothelial junctional integrity and porcine microvascular permeability J. Physiol., January 1, 2004; 554(1): 78 - 88. [Abstract] [Full Text] [PDF]

				E. B. Uglow, S. Slater, G. B. Sala-Newby, C. M. Aguilera-Garcia, G. D. Angelini, A. C. Newby, and S. J. George Dismantling of Cadherin-Mediated Cell-Cell Contacts Modulates Smooth Muscle Cell Proliferation Circ. Res., June 27, 2003; 92(12): 1314 - 1321. [Abstract] [Full Text] [PDF]

				K. Xiao, D. F. Allison, M. D. Kottke, S. Summers, G. P. Sorescu, V. Faundez, and A. P. Kowalczyk Mechanisms of VE-cadherin Processing and Degradation in Microvascular Endothelial Cells J. Biol. Chem., May 23, 2003; 278(21): 19199 - 19208. [Abstract] [Full Text] [PDF]

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				Y. Tanaka, H. Nakanishi, S. Kakunaga, N. Okabe, T. Kawakatsu, K. Shimizu, and Y. Takai Role of Nectin in Formation of E-Cadherin-based Adherens Junctions in Keratinocytes: Analysis with the N-Cadherin Dominant Negative Mutant Mol. Biol. Cell, April 1, 2003; 14(4): 1597 - 1609. [Abstract] [Full Text] [PDF]

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				V Noe, B Fingleton, K Jacobs, H. Crawford, S Vermeulen, W Steelant, E Bruyneel, L. Matrisian, and M Mareel Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1 J. Cell Sci., January 1, 2001; 114(1): 111 - 118. [Abstract] [PDF]

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				M. Troxell, S Gopalakrishnan, J McCormack, B. Poteat, J Pennington, S. Garringer, E. Schneeberger, W. Nelson, and J. Marrs Inhibiting cadherin function by dominant mutant E-cadherin expression increases the extent of tight junction assembly J. Cell Sci., January 3, 2000; 113(6): 985 - 996. [Abstract] [PDF]

				O Huber, R Kemler, and D Langosch Mutations affecting transmembrane segment interactions impair adhesiveness of E-cadherin J. Cell Sci., January 12, 1999; 112(23): 4415 - 4423. [Abstract] [PDF]