spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ware, M. F.
Right arrow Articles by Lauffenburger, D. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ware, M. F.
Right arrow Articles by Lauffenburger, D. A.
Aaronson, S. A (1991). Growth factors and cancer. Science 254, 1146-1153.[Abstract/Free Full Text]

Ando, Y. and Jensen, P. J (1993). Epidermal growth factor and insulin-like growth factor I enhance keratinocyte migration. J.Invest. Dermatol 100, 633-639.[Medline]

Blay, J. and Brown, K. D (1985). Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells. J. Cell. Physiol 124, 107-112.[Medline]

Bornfeldt, K. E., Raines, E. W., Nakano, T., Graves, L. M., Krebs, E. G. and Ross, R (1994). Insulin-like growth factor-1 and platelet-derived growth factor-BB induce directed migration of human arterial smooth muscle cells via signalling pathways that are distinct from those of proliferation. J. Clin. Invest 93, 1266-1274.

Bornfeldt, K. E., Graves, L. M., Raines, E. W., Igarashi, Y., Wayman, G., Yamamura, S., Yatomi, Y., Sidhu, J. S., Krebs, E. G., Hakomori, S.-I., et al (1995). Sphingosine-1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction. J. Cell Biol 130, 193-206.[Abstract/Free Full Text]

Cha, D., O'Brien, P., O'Toole, E. A., Woodley, D. T. and Hudson, L. G (1996). Enhanced modulation of keratinocyte motility by transforming growth factor-(TGF- ) relative to epidermal growth factor (EGF). J. Invest. Dermatol 106, 590-597.[Medline]

Chakrabarty, S., Rajagopal, S. and Huang, S (1995). Expression of antisense epidermal growth factor receptor RNA downmodulates the malignant behavior of human colon cancer cells. Clin. Exp. Metast 13, 191-195.[Medline]

Chen, P., Gupta, K. and Wells, A (1994). Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis. J. Cell Biol 124, 547-555.[Abstract/Free Full Text]

Chen, P., Xie, H., Sekar, M. C., Gupta, K. B. and Wells, A (1994). Epidermal growth factor receptor-mediated cell motility: phospholipase C activity is required, but MAP kinase activity is not sufficient for induced cell movement. J. Cell Biol 127, 847-857.[Abstract/Free Full Text]

Chen, P., Murphy-Ullrich, J. and Wells, A (1996). A role for gelsolin in actuating EGF receptor-mediated cell motility. J. Cell Biol 134, 689-698.[Abstract/Free Full Text]

Chen, Z., Fisher, R. J., Riggs, C. W., Rhim, J. S. and Lautenberger, J. A (1997). Inhibition of vascular endothelial growth factor-induced enothelial cell migration by ETS1 antisense oligonucleotides. Cancer Res 57, 2013-2019.[Abstract/Free Full Text]

Chicoine, M. R. and Silbergeld, D. L (1995). The in vitro motility of human gliomas increases with increasing grade of malignancy. Cancer 75, 290-299.

Diakonova, M., Payrastre, B., van Velzen, A. G., Hage, W. J., van Bergen en Henegouwen, P. M. P., Boonstra, J., Cremers, F. F. M. and Humbel, B. M (1995). Epidermal growth factor induces rapid and transient association of phospholipase C-g1 with EGF-receptor and filamentous actin at membrane ruffles of A431 cells. J. Cell Sci 108, 2499-2509.[Abstract]

DiMilla, P. A., Stone, J. A., Quinn, J. A., Albelda, S. M. and Lauffenburger, D. A (1993). Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength. J. Cell Biol 122, 729-737.[Abstract/Free Full Text]

Duband, J.-L., Dufour, S., Yamada, S., Yamada, K. and Thiery, J.-P (1991). Neural crest cell locomotin is induced by antibodies to1 integrins: A tool for studying the roles of substratum molecular avidity and density in migration. J. Cell Sci 98, 517-532.[Abstract/Free Full Text]

Dunn, G. A (1983). Characterising a kinesis response: Time averaged measures of cell speed and directional persistence. Agents and Actions [Suppl.] 12, 14-33.[Medline]

Engebraaten, O., Bjerkvig, R., Pedersen, P. H. and Laerum, O. D (1993). Effects of EGF, bFGF, NGF and PDGF(bb) on cell proliferative, migratory and invasive capacities of human brain-tumour biopsies in vitro. Int. J. Cancer 53, 209-214.[Medline]

Gail, M. H. and Boone, C. W (1970). The locomotion of mouse fibroblasts in tissue culture. Biophys. J 10, 980-993.

Goodman, S., Risse, G. and von der Mark, K (1989). The E8 subfragment of laminin promotes locomotion of myoblasts over extracellular matrix. J. Cell Biol 109, 799-809.[Abstract/Free Full Text]

Klemke, R. L., Cai, S., Giannini, A. L., Gallagher, P. J., deLanerolle, P. and Cheresh, D. A (1997). Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol 137, 481-492.[Abstract/Free Full Text]

Komuro, H., and Rakic, P (1995). Dynamics of granule cell migration: A confocal microscopic study in acute cerebellar slice preparations. J. Neurosci 15, 1110-1120.[Abstract]

Kundra, V., Escobedo, J. A., Kazlauskas, A., Kim, H. K., Rhee, S. G., Williams, L. T. and Zetter, B. R (1994). Regulation of chemotaxis by the platelet-derived growth factor receptor-. Nature 367, 474-476.[Medline]

Lauffenburger, D. A. and Horwitz, A. F (1996). Cell migration: a physically integrated molecular process. Cell 84, 359-369.[Medline]

Li, X. B., Nagayasu, H., Hamada, J., Hosokawa, M. and Takeichi, N (1993). Enhancement of tumorigenicity and invasion capacity of rat mammary adenocarcinoma cells by epidermal growth factor and transforming growth factor-beta. Jpn J. Cancer Res 84, 1145-1149.[Medline]

Maldonado, B. A. and Furcht, L. T (1995). Epidermal growth factor stimulates integrin-mediated cell migration of cultured human corneal epithelial cells on fibronectin and arginine-glycine-aspartic acid peptide. Invest. Ophthalmol. Visual Sci 36, 2120-2126.[Abstract/Free Full Text]

Matthay, M. A., Thiery, J. P., Lafont, F., Stampfer, F. and Boyer, B (1993). Transient effect of epidermal growth factor on the motility of an immortalized mammary epithelial cell line. J. Cell Sci 106, 869-878.[Abstract]

Nelson, J., Allen, W. E., Scott, W. N., Bailie, J. R., Walker, B., McFarren, N. V. and Wilson, D. J (1995). Murine epidermal growth factor (EGF) fragment (33-42) inhibits both EGF-and laminin-dependent enothelial cell motility and angiogenesis. Cancer Res 55, 3772-3776.[Abstract/Free Full Text]

Othmer, H. G., Dunbar, S. R. and Alt, W (1988). Models of dispersal in biological systems. J. Math. Biol 26, 263-298.[Medline]

Palecek, S. P., Loftus, J. C., Ginsburg, M. H., Lauffenburger, D. A. and Horwitz, A. F (1997). Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness. Nature 385, 537-540.[Medline]

Pruss, R. M. and Herschman, H. R (1977). Variants of 3T3 cells lacking mitogenic response to epidermal growth factor. Proc. Nat. Acad. Sci. USA 74, 3918-3921.[Abstract/Free Full Text]

Reddy, C. C., Wells, A. and Lauffenburger, D (1994). Proliferative response of fibroblasts expressing internalization-deficient EGF receptors is altered via differential EGF depletion effects. Biotech. Progr 10, 377-384.[Medline]

Ridley, A. J. and Hall, A (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.[Medline]

Ridley, A. J., Paterson, H. F., Johnston, C. L., Diekmann, D. and Hall, A (1992). The small GTP binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410.[Medline]

Ridley, A. J., Comoglio, P. M. and Hall, A (1995). Regulation of scatter factor/hepatocyte growth factor responses by ras, rac, and rho in MDCK cells. Mol. Cell Biol 15, 1110-1122.[Abstract]

Segall, J. E., Tyerech, S., Boselli, L., Masseling, S., Helft, J., Chan, A., Jones, J. and Condeelis, J (1996). EGF stimulates lamellipod extension in metastatic mammary adenocarcinoma cells by an actin-dependent mechanism. Clin. Exp. Metast 14, 61-72.[Medline]

Siegal, G. P., Wang, M.-H., Rinehart, C. A., Kennedy, J. W., Goodly, L. J., Miller, Y., Kaufman, D. G. and Singh, R. K (1993). Development of a novel human extracellular matrix for quantitation of the invasiveness of human cells. Cancer Lett 69, 123-132.[Medline]

Tessier-Lavigne, M. and Goodman, C. S (1996). The molecular biology of axon guidance. Science 274, 1123-1133.[Abstract/Free Full Text]

Thommen, R., Humar, R., Misevic, G., Pepper, M. S., Hahn, A. W., John, M. and Battegay, E. J (1997). PDGF-BB increases endothelial migration on cord movements during angiogenesis in vitro. J. Cell. Biochem 64, 403-413.[Medline]

Turner, T., Chen, P., Goodly, L. J. and Wells, A (1996). EGF receptor signaling enhances in vivo invasiveness of DU-145 human prostate carcinoma cells. Clin. Exp. Metast 14, 409-418.[Medline]

Ushiro, S., Ono, M., Izumi, H., Kohno, K., Taniguchi, N., Higashiyama, S. and Kuwano, M (1996). Heparin-binding epidermal growth factor-like growth factor: p91 activation induction of plasminogen activator/inhibitor, and tubular morphogenesis in human microvascular endothelial cells. Jpn J. Cancer Res 87, 68-77.[Medline]

Wells, A. and Bishop, J. M (1988). Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB. Proc. Nat. Acad. Sci. USA 85, 7597-7601.[Abstract/Free Full Text]

Wells, A., Welsh, J. B., Lazar, C. S., Wiley, H. S., Gill, G. N. and Rosenfeld, M. G (1990). Ligand-induced transformation by a non-internalizing EGF receptor. Science 247, 962-964.[Abstract/Free Full Text]

Welsh, J. B., Gill, G. N., Rosenfeld, M. G. and Wells, A (1991). A negative feedback loop attenuates EGF-induced morphological changes. J. Cell Biol 114, 533-543.[Abstract/Free Full Text]

Wennstrom, S., Siegbahn, A., Yokote, K., Arvidsson, A. K., Heldin, C. H., Mori, S. and Claesson-Welsh, L (1994). Membrane ruffling and chemotaxis transduced by the PBDF-receptor require the binding site for phosphatidylinositol 3 kinase. Oncogene 9, 651-660.[Medline]

Wijelath, E. S., Carlsen, B., Cole, T., Chen, J., Kothari, S. and Hammond, W. P (1997). Oncostatin M induces basic fibroblast growth factor expression in endothelial cells and promotes endothelial cell proliferation, migration and spindle morphology. J. Cell Sci 110, 871-879.[Abstract]

Wilson, S. E., He, Y. G., Weng, J., Zieske, J. D., Jester, J. V. and Schultz, G. S (1994). Effect of epidermal growth factor, hepatocyte growth factor, and keratinocyte growth factor, on proliferation, motility, and differentiation of human corneal epithelial cells. Exp. Eye Res 59, 665-678.[Medline]

Xie, H., Turner, T., Wang, M.-H., Singh, R. K., Siegal, G. P. and Wells, A (1995). In vitro invasiveness of DU-145 human prostate carcinoma cells is modulated by EGF receptor-mediated signals. Clin. Exp. Metast 13, 407-419.[Medline]

Xie, H., Pallero, M. A., Gupta, D., Chang, P., Ware, M. F., Witke, W., Kwiatkowski, D. J., Lauffenburger, D. A., Murphy-Ullrich, J. E. and Wells, A (1998). EGF receptor regulation of cell motility: EGF induces disassembly of focal adhesions independently of the motility-associated PLCsignaling pathway. J. Cell Sci 111, 615-624.[Abstract]




This article has been cited by other articles:


Home page
Mol. Biol. CellHome page
H.-D. Kim, T. W. Guo, A. P. Wu, A. Wells, F. B. Gertler, and D. A. Lauffenburger
Epidermal Growth Factor-induced Enhancement of Glioblastoma Cell Migration in 3D Arises from an Intrinsic Increase in Speed But an Extrinsic Matrix- and Proteolysis-dependent Increase in Persistence
Mol. Biol. Cell, October 1, 2008; 19(10): 4249 - 4259.
[Abstract] [Full Text] [PDF]


Home page
Biophys. JHome page
J. M. Haugh
Deterministic Model of Dermal Wound Invasion Incorporating Receptor-Mediated Signal Transduction and Spatial Gradient Sensing
Biophys. J., April 1, 2006; 90(7): 2297 - 2308.
[Abstract] [Full Text] [PDF]


Home page
Endocr Relat CancerHome page
T L Veveris-Lowe, M G Lawrence, R L Collard, L Bui, A C Herington, D L Nicol, and J A Clements
Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer cells
Endocr. Relat. Cancer, September 1, 2005; 12(3): 631 - 643.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
W. S. Carbonell, S.-I. Murase, A. F. Horwitz, and J. W. Mandell
Migration of Perilesional Microglia after Focal Brain Injury and Modulation by CC Chemokine Receptor 5: An In Situ Time-Lapse Confocal Imaging Study
J. Neurosci., July 27, 2005; 25(30): 7040 - 7047.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
L. Satish, H. C. Blair, A. Glading, and A. Wells
Interferon-Inducible Protein 9 (CXCL11)-Induced Cell Motility in Keratinocytes Requires Calcium Flux-Dependent Activation of {micro}-Calpain
Mol. Cell. Biol., March 1, 2005; 25(5): 1922 - 1941.
[Abstract] [Full Text] [PDF]


Home page
Biophys. JHome page
B. D. Harms, G. M. Bassi, A. R. Horwitz, and D. A. Lauffenburger
Directional Persistence of EGF-Induced Cell Migration Is Associated with Stabilization of Lamellipodial Protrusions
Biophys. J., February 1, 2005; 88(2): 1479 - 1488.
[Abstract] [Full Text] [PDF]


Home page
Sci SignalHome page
A. Wells and L. Lillien
Attraction or Repulsion: A Matter of Individual Taste?
Sci. Signal., October 5, 2004; 2004(253): pe47 - pe47.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
A. Iwabu, K. Smith, F. D. Allen, D. A. Lauffenburger, and A. Wells
Epidermal Growth Factor Induces Fibroblast Contractility and Motility via a Protein Kinase C {delta}-dependent Pathway
J. Biol. Chem., April 9, 2004; 279(15): 14551 - 14560.
[Abstract] [Full Text] [PDF]


Home page
Biophys. JHome page
Y.-T. Shiu, S. Li, W. A. Marganski, S. Usami, M. A. Schwartz, Y.-L. Wang, M. Dembo, and S. Chien
Rho Mediates the Shear-Enhancement of Endothelial Cell Migration and Traction Force Generation
Biophys. J., April 1, 2004; 86(4): 2558 - 2565.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
H. Shiraha, A. Glading, J. Chou, Z. Jia, and A. Wells
Activation of m-Calpain (Calpain II) by Epidermal Growth Factor Is Limited by Protein Kinase A Phosphorylation of m-Calpain
Mol. Cell. Biol., April 15, 2002; 22(8): 2716 - 2727.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
R. S. Sawhney, G.-H. K. Zhou, L. E. Humphrey, P. Ghosh, J. I. Kreisberg, and M. G. Brattain
Differences in Sensitivity of Biological Functions Mediated by Epidermal Growth Factor Receptor Activation with Respect to Endogenous and Exogenous Ligands
J. Biol. Chem., January 4, 2002; 277(1): 75 - 86.
[Abstract] [Full Text]


Home page
J. Cell Sci.Home page
S. C. Kirkland and K. Henderson
Collagen IV synthesis is restricted to the enteroendocrine pathway during multilineage differentiation of human colorectal epithelial stem cells
J. Cell Sci., January 6, 2001; 114(11): 2055 - 2064.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
S. Franitza, R. Hershkoviz, N.'a. Kam, N. Lichtenstein, G. G. Vaday, R. Alon, and O. Lider
TNF-{alpha} Associated with Extracellular Matrix Fibronectin Provides a Stop Signal for Chemotactically Migrating T Cells
J. Immunol., September 1, 2000; 165(5): 2738 - 2747.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
A. Glading, P. Chang, D. A. Lauffenburger, and A. Wells
Epidermal Growth Factor Receptor Activation of Calpain Is Required for Fibroblast Motility and Occurs via an ERK/MAP Kinase Signaling Pathway
J. Biol. Chem., January 28, 2000; 275(4): 2390 - 2398.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
M. A. Adelsman, J. B. McCarthy, and Y. Shimizu
Stimulation of beta 1-Integrin Function by Epidermal Growth Factor and Heregulin-beta Has Distinct Requirements for erbB2 but a Similar Dependence on Phosphoinositide 3-OH Kinase
Mol. Biol. Cell, September 1, 1999; 10(9): 2861 - 2878.
[Abstract] [Full Text]


Home page
JCBHome page
J. Gu, M. Tamura, R. Pankov, E. H.J. Danen, T. Takino, K. Matsumoto, and K. M. Yamada
Shc and FAK Differentially Regulate Cell Motility and Directionality Modulated by PTEN
J. Cell Biol., July 26, 1999; 146(2): 389 - 404.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
H. Shiraha, A. Glading, K. Gupta, and A. Wells
IP-10 Inhibits Epidermal Growth Factor–induced Motility by Decreasing Epidermal Growth Factor Receptor–mediated Calpain Activity
J. Cell Biol., July 12, 1999; 146(1): 243 - 254.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. Sakai, J. M. de la Pena, and D. F. Mosher
Synergism among Lysophosphatidic Acid, beta 1A Integrins, and Epidermal Growth Factor or Platelet-derived Growth Factor in Mediation of Cell Migration
J. Biol. Chem., May 28, 1999; 274(22): 15480 - 15486.
[Abstract] [Full Text] [PDF]


Home page
Mol. Biol. CellHome page
M. Zhao, A. Dick, J. V. Forrester, and C. D. McCaig
Electric Field-directed Cell Motility Involves Up-regulated Expression and Asymmetric Redistribution of the Epidermal Growth Factor Receptors and Is Enhanced by Fibronectin and Laminin
Mol. Biol. Cell, April 1, 1999; 10(4): 1259 - 1276.
[Abstract] [Full Text]


Home page
J. Biol. Chem.Home page
D. Mielenz, S. Hapke, E. Poschl, H. von der Mark, and K. von der Mark
The Integrin alpha 7 Cytoplasmic Domain Regulates Cell Migration, Lamellipodia Formation, and p130CAS/Crk Coupling
J. Biol. Chem., April 13, 2001; 276(16): 13417 - 13426.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
V. Ronfard and Y. Barrandon
Migration of keratinocytes through tunnels of digested fibrin
PNAS, April 10, 2001; 98(8): 4504 - 4509.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
G. Maheshwari, H. S. Wiley, and D. A. Lauffenburger
Autocrine epidermal growth factor signaling stimulates directionally persistent mammary epithelial cell migration
J. Cell Biol., December 24, 2001; 155(7): 1123 - 1128.
[Abstract] [Full Text] [PDF]


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ware, M. F.
Right arrow Articles by Lauffenburger, D. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ware, M. F.
Right arrow Articles by Lauffenburger, D. A.