Rescue of the mutant phenotype by reexpression of full-length vinculin in null F9 cells; effects on cell locomotion by domain deleted vinculin

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Belkin, A. M. and Koteliansky, V. E (1987). Interaction of iodinated vinculin, meta-vinculin and-actinin with cytoskeletal proteins. FEBS Lett 220, 291-294.[Medline]

Brindle, P. J., Holt, M. R., Davies, J. E., Price, J. J. and Critchley, D. R (1996). The focal adhesion vasodilator-stimulated phosphoprotein (VASP)binds to the proline-rich domain in vinculin. Biochem. J 318, 753-757.

Burridge, K. and Mangeat, P (1984). An interaction between vinculin and talin. Nature 308, 744-746.[Medline]

Burridge, K., Fath, K., Kelly, T., Nuckolls, G. and Turner, C (1988). Focal adhesions:transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol 4, 487-525.

Calogero, A., Samuels, M., Darland, T., Edwards, S. A., Kemler, R. and Adamson, E. D (1991). Over-expression of uvomorulin in a compaction-negative F9 mutant cell line. Dev. Biol 146, 499-508.[Medline]

Coll, J. L., Ben-Ze'ev, A., Ezzell, R. M., Rodriguez Fernandez, J. L., Baribault, H., Oshima, R. G. and Adamson, E. D (1995). Targeted disruption of the vinculin gene in F9 and ES cells changes cell morphology, adhesion and locomotion. Proc. Nat. Acad. Sci. USA 92, 9161-9165.[Abstract/Free Full Text]

Critchley, D. R., Gilmore, A., Hemmings, L., Jackson, P., McGregor, A., Ohanian, V., Patel, B., Waites, G. and Wood, C (1991). Cytoskeletal proteins in adherens-type cell-matrix junctions. Biochem. Soc. Trans 19, 1028-1033.[Medline]

Geiger, B. and Ginsberg, D (1991). The cytoplasmic domain of adherens-type junctions. Cell Motil. Cytoskel 20, 1-6.[Medline]

Gilmore, A. P., Jackson, P., Waites, G. T. and Critchley, D. R (1992). Further characterisation of the talin-binding site in the cytoskeletal protein vinculin. J. Cell Sci 103, 719-731.[Abstract]

Gimona, M., Small, J. V., Moeremans, M., Van Damme, J., Puype, M. and Vandekerckhove, J (1988). Porcine vinculin and metavinculin differ by a 68-residue insert located close to the carboxy-terminal part of the molecule. EMBO J 7, 2329-2334.[Medline]

Goldmann, W. H. and Ezzell, R. M (1996). Viscoelasticity in wild-type and vinculin-deficient (5.51) mouse F9 embryonic carcinoma cells examined by atomic force microscopy and rheology. Exp. Cell Res 226, 234-237.[Medline]

Grover, A. and Adamson, E. D (1986). Conditions affecting the differentiation of F9 teratocarcinoma cells: Potentiation of response by cyclic AMP. In Vitro Cell. Dev. Biol 22, 280-284.[Medline]

Grover, A., Rosenstraus, M. J., Sterman, B., Snook, M. E. and Adamson, E. D (1987). An adhesion-defective variant of F9 embryonal carcinoma cells fails to differentiate into visceral endoderm. Dev. Biol 119, 1-11.[Medline]

Ito, S., Werth, D. K., Richert, N. D. and Pastan, I (1983). Vinculin phosphorylation by src kinase. Interaction of vinculin with phospholipid vesicles. J. Biol. Chem 258, 14626-14631.[Abstract/Free Full Text]

Johnson, R. P. and Craig, S. W (1994). An intramolecular association between the head and tail domains of vinculin modulates talin binding. J. Biol. Chem 269, 12611-12619.[Abstract/Free Full Text]

Johnson, R. P. and Craig, S. W (1995). The carboxy-terminal tail domain of vinculin contains a cryptic binding site for acidic phospholipids. Biochem. Biophys. Res. Commun 210, 159-164.[Medline]

Johnson, R. P. and Craig, S. W (1995). F-actin binding site masked by the intramolecular association of vinculin head and tail domains. Nature 373, 261-264.[Medline]

Jones, P., Jackson, P., Price, G. J., Patel, B., Ohanion, V., Lear, A. L. and Critchley, D. R (1989). Identification of a talin binding site in the cytoskeletal protein vinculin. J. Cell Biol 109, 2917-2927.[Abstract/Free Full Text]

Kroemker, M., Rudiger, A. H., Jockusch, B. M. and Rudiger, M (1994). Intramolecular interactions in vinculin control alpha-actinin binding to the vinculin head. FEBS Lett 355, 259-262.[Medline]

Laemmli, U. K (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.[Medline]

Lee, S. W. and Otto, J. J (1997). Vinculin and talin- kinetics of entry and exit from the cytoskeletal pool. Cell Motil. Cytoskel 36, 101-111.[Medline]

Mansfield, P. J. and Suchard, S. J (1994). Thrombospondin promotes chemotaxis and haptotaxis of human peripheral blood monocytes. J. Immunol 153, 4219-4229.[Abstract]

Menkel, A. R., Kroemker, M., Bubeck, P., Ronsiek, M., Nikolai, G. andJockusch, B. M (1994). Characterization of an F-actin-binding domain in the cytoskeletal protein vinculin. J. Cell Biol 126, 1231-1240.[Abstract/Free Full Text]

Moiseyeva, E. P., Weller, P. A., Zhidhova, N. I., Corben, E. B., Patel, B., Jasinska, I., Koteliansky, V. E. and Critchley, D. R (1993). Organization of the human gene encoding the cytoskeletal protein vinculin and the sequence of the vinculin promoter. J. Biol. Chem 268, 4318-4325.[Abstract/Free Full Text]

Niggli, V., Sommer, L., Brunner, J. and Burger, M. M (1990). Interaction in situ of the cytoskeletal protein vinculin with bilayers studied by introducing a photoactivatable fatty acid into living chicken embryo fibroblasts. Eur. J. Biochem 187, 111-117.[Medline]

Niwa, H., Yamamura, K.-i. and Miyazaki, J.-i (1991). Efficient selection for high expression transfectants with a novel eukaryotic vector. Gene 108, 193-199.[Medline]

Otey, C. A., Pavalko, F. M. and Burridge, K (1990). An interaction between alpha-actinin and the-1 integrin subunit in vitro. J. Cell Biol 111, 721-729.[Abstract/Free Full Text]

Pavalko, F. M. and Burridge, K (1991). Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of-actinin. J. Cell Biol 114, 481-491.[Abstract/Free Full Text]

Pavalko, F. M., Otey, C. A., Simon, K. O. and Burridge, K (1991). -actinin: a direct link between actin and integrins. Biochem. Soc. Trans 19, 1065-1069.[Medline]

Price, G. J., Jones, P., Davison, M. D., Patel, B., Bendori, R., Geiger, B. and Critchley, D. R (1989). Primary sequence and domain structure of chicken vinculin. J. Biochem 259, 453-461.

Samuels, M., Ezzell, R. M., Cardozo, T. J., Critchley, D. R., Coll, J.-L. and Adamson, E. D (1993). Expression of chicken vinculin complements the adhesion-defective phenotype of a mutant mouse F9 embryonal carcinoma cell. J. Cell Biol 121, 909-921.[Abstract/Free Full Text]

Southwick, F. S., Laine, R. O., Zeile, W., Kang, F. and Purich, D. L (1996). vinculin proteolysis: a molecular switch for actin-based motility of Shigella. Mol. Biol. Cell 7, 380-.

Southwick, F. S. and Purich, D. L (1996). Intracellular pathogenesis of listeriosis. New Eng. J. Med 334, 770-776.[Free Full Text]

Stephens, L. E., Sonne, J. E., Fitzgerald, M. L. and Damsky, C. H (1993). Targeted deletion of1 integrins in F9 embryonal carcinoma cells affects morphological differentiation but not tissue-specific gnene expression. J. Cell Biol 123, 1607-1620.[Abstract/Free Full Text]

Tempel, M., Goldmann, W. H., Isenberg, G. and Sackmann, E (1995). Interaction of the 47-kDa talin fragment and the 32-kDa vinculin fragment with acidic phospholipids: a computer analysis. Biophys. J 69, 228-241.[Abstract/Free Full Text]

Turner, C. E. and Burridge, K (1989). Detection of metavinculin in human platelets using a modified talin overlay assay. Eur. J. Cell Biol 49, 202-206.[Medline]

Turner, C. E., Glenney, J. R. Jr and Burridge, K (1990). Paxillin: A new vinculin-binding protein present in focal adhesions. J. Cell Biol 111, 1059-1068.[Abstract/Free Full Text]

Volberg, T., Geiger, B., Kam, Z., Pankov, R., Simcha, I., Sabanay, I., Coll, J.-L., Adamson, E. D. and Ben-Ze'ev, A (1995). Focal adhesion formation by F9 embryonal carcinoma cells after vinculin gene disruption. J. Cell Sci 108, 2253-2260.[Abstract]

Weekes, J., Barry, S. T. and Critchley, D. R (1996). Acidic phospholipids inhibit the intramolecular association between the N-and C-terminal regions of vinculin, exposing actin-binding and protein kinase C phosphorylation sites. Biochem. J 314, 827-832.

Wood, C. K., Turner, C. E., Jackson, P. and Critchley, D. R (1994). Characterisation of the paxillin-binding site and the C-terminal focal adhesion targeting sequence in vinculin. J. Cell Sci 107, 709-717.[Abstract]

Wu, J.-X. and Adamson, E. D (1996). Kinase-negative mutant epidermal growth factor receptor (EGFR) expression during embryonal stem cell differentiation favours EGFR-independent lineages. Development 122, 3331-3342.[Abstract]

Xu, W., Baribault, H. and Adamson, E. D (1998). Vinculin knockout results in multiple organ defects during embryonic development. Development 125, 327-337.[Abstract]

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				J. J. Northey, J. Chmielecki, E. Ngan, C. Russo, M. G. Annis, W. J. Muller, and P. M. Siegel Signaling through ShcA Is Required for Transforming Growth Factor {beta}- and Neu/ErbB-2-Induced Breast Cancer Cell Motility and Invasion Mol. Cell. Biol., May 15, 2008; 28(10): 3162 - 3176. [Abstract] [Full Text] [PDF]

				C. Le Clainche and M.-F. Carlier Regulation of Actin Assembly Associated With Protrusion and Adhesion in Cell Migration Physiol Rev, April 1, 2008; 88(2): 489 - 513. [Abstract] [Full Text] [PDF]

				C. T. Mierke, P. Kollmannsberger, D. Paranhos Zitterbart, J. Smith, B. Fabry, and W. H. Goldmann Mechano-Coupling and Regulation of Contractility by the Vinculin Tail Domain Biophys. J., January 15, 2008; 94(2): 661 - 670. [Abstract] [Full Text] [PDF]

				H. Chen, D. M. Choudhury, and S. W. Craig Coincidence of Actin Filaments and Talin Is Required to Activate Vinculin J. Biol. Chem., December 29, 2006; 281(52): 40389 - 40398. [Abstract] [Full Text] [PDF]

				K. A. DeMali, A. L. Jue, and K. Burridge IpaA Targets beta1 Integrins and Rho to Promote Actin Cytoskeleton Rearrangements Necessary for Shigella Entry J. Biol. Chem., December 22, 2006; 281(51): 39534 - 39541. [Abstract] [Full Text] [PDF]

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				N. D. Gallant, K. E. Michael, and A. J. Garcia Cell Adhesion Strengthening: Contributions of Adhesive Area, Integrin Binding, and Focal Adhesion Assembly Mol. Biol. Cell, September 1, 2005; 16(9): 4329 - 4340. [Abstract] [Full Text] [PDF]

				H. Chen, D. M. Cohen, D. M. Choudhury, N. Kioka, and S. W. Craig Spatial distribution and functional significance of activated vinculin in living cells J. Cell Biol., May 9, 2005; 169(3): 459 - 470. [Abstract] [Full Text] [PDF]

				I. Chandrasekar, T. E. B. Stradal, M. R. Holt, F. Entschladen, B. M. Jockusch, and W. H. Ziegler Vinculin acts as a sensor in lipid regulation of adhesion-site turnover J. Cell Sci., April 1, 2005; 118(7): 1461 - 1472. [Abstract] [Full Text] [PDF]

				M. C. Subauste, P. Nalbant, E. D. Adamson, and K. M. Hahn Vinculin Controls PTEN Protein Level by Maintaining the Interaction of the Adherens Junction Protein {beta}-Catenin with the Scaffolding Protein MAGI-2 J. Biol. Chem., February 18, 2005; 280(7): 5676 - 5681. [Abstract] [Full Text] [PDF]

				Z. Zhang, G. Izaguirre, S.-Y. Lin, H. Y. Lee, E. Schaefer, and B. Haimovich The Phosphorylation of Vinculin on Tyrosine Residues 100 and 1065, Mediated by Src Kinases, Affects Cell Spreading Mol. Biol. Cell, September 1, 2004; 15(9): 4234 - 4247. [Abstract] [Full Text] [PDF]

				M. C. Subauste, O. Pertz, E. D. Adamson, C. E. Turner, S. Junger, and K. M. Hahn Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility J. Cell Biol., May 10, 2004; 165(3): 371 - 381. [Abstract] [Full Text] [PDF]

				K. A. DeMali, C. A. Barlow, and K. Burridge Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion J. Cell Biol., December 9, 2002; 159(5): 881 - 891. [Abstract] [Full Text] [PDF]

				J. K. G. Crean, D. Finlay, M. Murphy, C. Moss, C. Godson, F. Martin, and H. R. Brady The Role of p42/44 MAPK and Protein Kinase B in Connective Tissue Growth Factor Induced Extracellular Matrix Protein Production, Cell Migration, and Actin Cytoskeletal Rearrangement in Human Mesangial Cells J. Biol. Chem., November 8, 2002; 277(46): 44187 - 44194. [Abstract] [Full Text] [PDF]

				M. Chellaiah, N. Kizer, M. Silva, U. Alvarez, D. Kwiatkowski, and K. A. Hruska Gelsolin Deficiency Blocks Podosome Assembly and Produces Increased Bone Mass and Strength J. Cell Biol., February 21, 2000; 148(4): 665 - 678. [Abstract] [Full Text] [PDF]

				R. P. Johnson and S. W. Craig Actin Activates a Cryptic Dimerization Potential of the Vinculin Tail Domain J. Biol. Chem., January 7, 2000; 275(1): 95 - 105. [Abstract] [Full Text] [PDF]

				X. Fang, M. A. Burg, D. Barritt, K. Dahlin-Huppe, A. Nishiyama, and W. B. Stallcup Cytoskeletal Reorganization Induced by Engagement of the NG2 Proteoglycan Leads to Cell Spreading and Migration Mol. Biol. Cell, October 1, 1999; 10(10): 3373 - 3387. [Abstract] [Full Text]

				P. A. Steimle, J. D. Hoffert, N. B. Adey, and S. W. Craig Polyphosphoinositides Inhibit the Interaction of Vinculin with Actin Filaments J. Biol. Chem., June 25, 1999; 274(26): 18414 - 18420. [Abstract] [Full Text] [PDF]

				M. Watabe-Uchida, N. Uchida, Y. Imamura, A. Nagafuchi, K. Fujimoto, T. Uemura, S. Vermeulen, F. van Roy, E. D. Adamson, and M. Takeichi alpha -Catenin-Vinculin Interaction Functions to Organize the Apical Junctional Complex in Epithelial Cells J. Cell Biol., August 10, 1998; 142(3): 847 - 857. [Abstract] [Full Text] [PDF]