Localization of fibronectin matrix assembly sites on fibroblasts and endothelial cells

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Abercrombie, M., Heaysman, J. and Pegrum, S. M (1971). The locomotion of fibroblasts in culture. Exp. Cell Res 67, 359-367.[Medline]

Aguirre, K. M., McCormick, R. J. and Schwarzbauer, J. E (1994). Fibronectin self association is mediated by complementary sites within the amino terminal one-third of the molecule. J. Biol. Chem 269, 27863-27868.[Abstract/Free Full Text]

Avnur, Z. and Geiger, B (1981). The removal of extracellular fibronectin from areas of cell-substrate contact. Cell 25, 121-132.[Medline]

Blystone, S. D., Weston, L. K. and Kaplan, J. E (1991). Fibronectin dependent macrophage fibrin binding. Blood 78, 2900-2907.[Abstract/Free Full Text]

Burridge, K. and Connell, L (1983). Talin: a cytoskeletal componentconcentrated at adhesion plaques and other sites of actin-membrane interaction. Cell Motil 3, 405-417.[Medline]

Burridge, K., Fath, K., Kelly, T., Muckolis, B. and Turner, C (1988). Focal adhesions: Transmembrane junctions between the extracellular matrix and the cytoskeleton. Annu. Rev. Cell Biol 4, 487-525.

Chen, W. and Singer, S. J (1982). Immunoelectron microscopic studies of the sites of cell-substratum and cell-cell contacts in cultured fibroblasts. J. Cell Biol 95, 205-222.[Abstract/Free Full Text]

Chen, W., Hasegawa, E., Hasegawa, T., Weinstock, C. and Yamada, K. M (1985). Development of cell surface linkage complexes in cultured fibroblasts. J. Cell Biol 100, 1103-1114.[Abstract/Free Full Text]

Cooper, J. A (1987). Effects of cytochalasin and phalloidin on actin. J. Cell Biol 105, 1473-1478.[Free Full Text]

Dunleavy, J. R. and Couchman, J. R (1993). Controlled induction of focal adhesion disassembly and migration in primary fibroblasts. J. Cell Sci 105, 489-500.[Abstract]

Dzamba, B. J., Bultmann, H., Akiyama, S. K. and Peters, D. M (1994). Substrate-specific binding of the amino terminus of fibronectin to an integrin complex in focal adhesions. J. Biol. Chem 269, 19646-19652.[Abstract/Free Full Text]

Fogerty, F. J., Akiyama, S. K., Yamada, K. M. and Mosher, D. F (1990). Inhibition of binding of fibronectin to matrix assembly sites by anti-integrin (5 1) antibodies. J. Cell Biol 111, 699-708.[Abstract/Free Full Text]

Geiger, B., Tokuyasu, K. T., Dutton, A. H. and Singer, S. J (1980). Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes. Proc. Nat. Acad. Sci. USA 77, 4127-4131.[Abstract/Free Full Text]

Grinnell, F (1986). Focal adhesion sites and the removal of substratum-bound fibronectin. J. Cell Biol 103, 2697-2706.[Abstract/Free Full Text]

Hocking, D. C., Sottile, J. and McKeown-Longo, P. J (1994). Fibronectin's III-1 module contains a conformation-dependent binding site for the amino-terminal region of fibronectin. J. Biol. Chem 269, 19183-19191.[Abstract/Free Full Text]

Hocking, D. C., Smith, R. K. and McKeown-Longo, P. J (1996). A novel role for the integrin-binding III10 module in fibronectin matrix assembly. J. Cell Biol 133, 431-444.[Abstract/Free Full Text]

Horwitz, A., Duggan, K., Buck, C. A., Beckerle, M. and Burridge, K (1986). Interactions of plasma membrane fibronectin receptor with talin- a transmembrane linkage. Nature 320, 531-533.[Medline]

Hyatt, S. L., Liao, L., Chapline, C. and Jaken, S (1994). Identification and characterization of-protein kinase C binding proteins in normal and transformed REF52 cells. Biochemistry 33, 1223-1228.[Medline]

Izzard, C. S. and Lochner, L. R (1976). Cell-to-substrate contacts in living fibroblasts: An interference reflexion study with an evaluation of the technique. J. Cell Sci 21, 129-159.[Abstract]

Jaken, S., Leach, K. and Klauck, L. R (1989). Association of type 3 protein kinase C with focal contacts in rat embryo fibroblasts. J. Cell Biol 109, 687-704.

Kowalczyk, A. and McKeown-Longo, P. J (1992). Basolateral distribution of fibronectin matrix assembly sites on vascular endothelial cells is regulated by substratum fibronectin. J. Cell. Physiol 152, 126-134.[Medline]

Larjava, H., Peltonen, J., Akiyama, S. K., Yamada, S. S., Gralnick, H. R., Uitto, J. and Yamada, K. M (1990). Novel function for 1 integrins in keratinocyte cell-cell interactions. J. Cell Biol 110, 803-815.[Abstract/Free Full Text]

Lazarides, E. and Burridge, K (1975). -Actinin: immunofluorescent localization of a muscle structural protein in nonmuscle cells. Cell 6, 289-298.[Medline]

Lo, S. H. and Chen, L. B (1994). Focal adhesion as a signal transduction organelle. Cancer Met. Rev 13, 9-24.[Medline]

Lotz, M. M., Burdsal, C. A., Erickson, H. P. and McClay, D. R (1989). Cell adhesion to fibronectin and tenascin: quantitative measurements of initial binding and subsequent strengthening response. J. Cell Biol 109, 1795-1805.[Abstract/Free Full Text]

Mattey, D. L. and Garrod, D. R (1984). Organization of extracellular matrix by chick embryonic corneal epithelial cells in culture and the role of fibronectin in adhesion. J. Cell Sci 67, 171-188.[Abstract]

McDonald, J. A., Quade, B. J., Broekelmann, T. J., LaChance, R., Forsman, K., Hasegawa, E. and Akiyama, S (1987). Fibronectin's cell-adhesive domain and an amino-terminal matrix assembly domain participate in its assembly into fibroblast pericellular matrix. J. Biol. Chem 262, 2957-2967.[Abstract/Free Full Text]

McKeown-Longo, P. J. and Mosher, D. F (1985). Interaction of the 70 kilodalton amino-terminal fragment of fibronectin with the matrix-assembly receptor of fibroblasts. J. Cell Biol 100, 364-374.[Abstract/Free Full Text]

Morla, A. and Ruoslahti, E (1992). A fibronectin self-assembly site involvedin fibronectin matrix assembly: Reconstruction in a synthetic peptide. J. Cell Biol 118, 421-429.[Abstract/Free Full Text]

Mosher, D. F., Sottile, J., Wu, C. and McDonald, J. A (1992). Assembly of extracellular matrix. Curr. Opin. Cell Biol 4, 810-818.[Medline]

Otey, C. A., Pavalko, F. M. and Burridge, K (1990). An interaction between-actinin and 1 integrin subunit in vitro. J. Cell Biol 111, 721-729.[Abstract/Free Full Text]

Petersen, T. E., Thorgersen, H. C., Skorstengaard, K., Vibe-Pedersen, K., Sahl, P., Sottrup-Jensen, L. and Magnusson, S (1983). Partial primary structure of bovine plasma fibronectin: three types of internal homology. Proc. Nat. Acad. Sci 80, 138-141.

Quade, B. J. and McDonald, J. A (1988). Fibronectin's amino-terminal matrix assembly site is located within the 29 kDa amino-terminal domain containing five Type I repeats. J. Biol. Chem 263, 19602-19609.[Abstract/Free Full Text]

Ridley, A. J. and Hall, A (1994). Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase. EMBO J 13, 2600-2610.[Medline]

Rohrschneider, L. R (1980). Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product. Proc. Nat. Acad. Sci. USA 77, 3514-3518.[Abstract/Free Full Text]

Schaller, M. D., Borgman, C. A., Cobb, B. S., Vines, R. R., Reynolds, A. B. and Parsons, J. T (1992). pp125FAK, a structurally distinctive protein-tyrosine kinase associated with focal adhesions. Proc. Nat. Acad. Sci. USA 89, 5192-5196.[Abstract/Free Full Text]

Schwartz, M. A. and Ingber, D. E (1994). Integrating with integrins. Mol. Biol. Cell 5, 389-393.[Abstract]

Seufferlein, T. and Rozengurt, E (1994). Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130.Signaling pathways and cross-talk with platelet-derived growth factor. J. Biol. Chem 269, 9345-9351.[Abstract/Free Full Text]

Sims, J. R., Karp, S. and Ingber, D. E (1992). Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape. J. Cell Sci 103, 1215-1222.[Abstract/Free Full Text]

Small, J. V. and Celis, J. E (1978). Filament arrangements in negatively stained cells: the organization of actin. J. Cell Biol 16, 308-325.

Small, J. V (1988). The actin cytoskeleton. Electron Microsc. Rev 1, 155-174.[Medline]

Turner, C. E., Glenney, J. R. Jr and Burridge, K (1990). Paxillin: a new vinculin-binding protein present in focal adhesions. J. Cell Biol 111, 1059-1068.[Abstract/Free Full Text]

Wang, N., Butler, J. P. and Ingber, D. E (1993). Mechanotransduction across the cell surface and through the cytoskeleton. Science 260, 1124-1127.[Abstract/Free Full Text]

Woods, A., Johansson, S. and Hook, M (1988). Fibronectin fibril formation involves cell interactions with two fibronectin domains. Exp. Cell Res 177, 272-283.[Medline]

Woods, A. and Couchman, J. R (1992). Protein kinase C involvement in focal adhesion formation. J. Cell Sci 101, 277-290.[Abstract/Free Full Text]

Wu, C., Keivens, V. M., O'Toole, T. E., McDonald, J. A. and Ginsberg, M. H (1995). Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix. Cell 83, 715-724.[Medline]

Yatohgo, T., Izumi, M., Kashiwagi, H. and Hayashi, M (1988). Novel purification of vitronectin from human plasma by heparin affinity chromatography. Cell Struct. Funct 13, 281-292.[Medline]

Zhang, Q., Checovich, W. J., Peters, D. M., Albrecht, R. M. and Mosher, D. F (1994). Modulation of cell surface fibronectin assembly sites by lysophosphotidic acid. J. Cell Biol 127, 1447-1459.[Abstract/Free Full Text]

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				R. Christopher, S. Judge, P. Vincent, P. Higgins, and P. McKeown-Longo The amino-terminal matrix assembly domain of fibronectin stabilizes cell shape and prevents cell cycle progression J. Cell Sci., January 10, 1999; 112(19): 3225 - 3235. [Abstract] [PDF]

				G Cali, C Mazzarella, M Chiacchio, R Negri, S. Retta, M Zannini, F Gentile, G Tarone, L Nitsch, and C Garbi RhoA activity is required for fibronectin assembly and counteracts beta1B integrin inhibitory effect in FRT epithelial cells J. Cell Sci., January 3, 1999; 112(6): 957 - 965. [Abstract] [PDF]

				Q. Zhang, T. Sakai, J. Nowlen, I. Hayashi, R. Fassler, and D. F. Mosher Functional beta 1-Integrins Release the Suppression of Fibronectin Matrix Assembly by Vitronectin J. Biol. Chem., January 1, 1999; 274(1): 368 - 375. [Abstract] [Full Text] [PDF]

				T. M. Curtis, R. F. Rotundo, P. A. Vincent, P. J. McKeown-Longo, and T. M. Saba TNF-alpha -induced matrix Fn disruption and decreased endothelial integrity are independent of Fn proteolysis Am J Physiol Lung Cell Mol Physiol, July 1, 1998; 275(1): L126 - L138. [Abstract] [Full Text] [PDF]

				T. Sakai, Q. Zhang, R. Fassler, and D. F. Mosher Modulation of beta 1A Integrin Functions by Tyrosine Residues in the beta 1 Cytoplasmic Domain J. Cell Biol., April 20, 1998; 141(2): 527 - 538. [Abstract] [Full Text] [PDF]

				C. Zhong, M. Chrzanowska-Wodnicka, J. Brown, A. Shaub, A. M. Belkin, and K. Burridge Rho-mediated Contractility Exposes a Cryptic Site in Fibronectin and Induces Fibronectin Matrix Assembly J. Cell Biol., April 20, 1998; 141(2): 539 - 551. [Abstract] [Full Text] [PDF]

				D. C. Hocking, J. Sottile, and P. J. McKeown-Longo Activation of Distinct alpha 5beta 1-mediated Signaling Pathways by Fibronectin's Cell Adhesion and Matrix Assembly Domains J. Cell Biol., April 6, 1998; 141(1): 241 - 253. [Abstract] [Full Text] [PDF]