Putative GTPase Gtr1p genetically interacts with the RanGTPase cycle in Saccharomyces cerevisiae

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Aebi, M., Clark, M. W., Vijayraghavan, U. and Abelson, J (1990). A yeast mutant, PRP20 , altered in mRNA metabolism and maintenance of the nuclear structure, is defective in a gene homologous to the human gene RCC1 which is involved in the control of chromosome condensation. Mol. Gen. Genet 224, 72-80.[Medline]

Amberg, D. C., Fleischmann, M., Stagljar, I., Cole, C. N. and Aebi, M (1993). Nuclear PRP20 protein is required for mRNA export. EMBO J 12, 233-241.[Medline]

Azuma, Y., Seino, H., Seki, T., Uzawa, S., Klebe, C., Ohba, T., Wittinghofer, A., Hayashi, N. and Nishimoto, T (1996). Conserved histidine residues of RCC1 are essential for nucleotide exchange on Ran. J. Biochem 120, 82-91.

Becker, J., Melchior, F., Gerke, V., Bischoff, F. R., Ponstingl, H. and Wittinghofer, A (1995). RNA1 encodes a GTPase-activating protein specific for Gsp1, the Ran/TC4 homologue of Saccharomyces cerevisiae. J. Biol. Chem 270, 11860-11865.[Abstract/Free Full Text]

Belanger, K. D., Kenna, M. A., Wei, S. and Davis, L (1994). Genetic and physical interactions between Srp1p and nuclear pore complex proteins Nup1p and Nup2p. J. Cell Biol 126, 619-630.[Abstract/Free Full Text]

Belhumeur, P., Lee, A., Tam, R., D'Paolo, T., Fortin, N. and Clark, M. W (1993). GSP1 and GSP2, genetic supressors of prp20-1 mutant in Saccharomyces cerevisiae : GTP-binding proteins involved in the maintenance of nuclear organization. Mol. Cell. Biol 13, 2152-2161.[Abstract/Free Full Text]

Benes, V., Hostomsky, Z., Arnold, L. and Paces, V (1993). M13 and pUC vectors with new unique restriction sites for cloning. Gene 130, 151-152.[Medline]

Bischoff, F. R. and Ponstingl, H (1991). Catalysis of guanine nucleotide exchange on Ran by the mitotic regulator RCC1. Nature 354, 80-82.[Medline]

Bischoff, F. R. and Ponstingl, H (1991). Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide. Proc. Nat. Acad. Sci. USA 88, 10830-10834.[Abstract/Free Full Text]

Bischoff, F. R., Klebe, C., Kretschmer, J., Wittinghofer, A. and Ponstingl, H (1994). RanGAP1 induces GTPase activity of nuclear Ras-related Ran. Proc. Nat. Acad. Sci. USA 91, 2587-2591.[Abstract/Free Full Text]

Bischoff, F. R., Krebber, H., Kempf, T., Hermes, I. and Ponstingl, H (1995). Human RanGTPase-activating protein RanGAP1 is a homologue of yeast Rna1p involved in mRNA processing and transport. Proc. Nat. Acad. Sci. USA 92, 1749-1753.[Abstract/Free Full Text]

Bun-ya, M., Harashima, S. and Oshima, Y (1992). Putative GTP-binding protein, Gtr1, associated with the function of the Pho84 inorganic phosphate transporter in Saccharomyces cerevisiae. Mol. Cell. Biol 12, 2958-2966.[Abstract/Free Full Text]

Boguski, M. and McCormick, F (1993). Proteins regulating Ras and its relatives. Nature 366, 643-653.[Medline]

Clark, K. L. and Sprague, G. F. Jr (1989). Yeast pheromone response pathway: Characterization of a suppressor that restores mating to receptor less mutants. Mol. Cell. Biol 9, 2682-2694.[Abstract/Free Full Text]

Corbett, A. H., Koepp, D. M., Schlenstedt, G., Lee, M. S., Hopper, A. K. and Silver, P. A (1995). Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import. J. Cell Biol 130, 1017-1026.[Abstract/Free Full Text]

Dasso, M., Nishitani, H., Kornbluth, S., Nishimoto, T. and Newport, J (1992). RCC1, a regulator of mitosis, is essential for DNA replication. Mol. Cell. Biol 12, 3337-3345.[Abstract/Free Full Text]

Dasso, M (1993). RCC1 in the cell cycle: The regulator of chromosome condensation takes on new roles. Trends Biochem. Sci 16, 96-101.

Drivas, G. T., Shih, A., Coutavas, E., Rush, M. G. and D'Eustachio, P (1990). Characterization of four novel RAS-related genes expressed in a human teratocarcinoma cell line. Mol. Cell. Biol 10, 1793-1798.[Abstract/Free Full Text]

Frasch, M (1991). The maternally expressed Drosophila gene encoding the chromatin-binding protein BJ1 is a homologue of the vertebrate gene regulator of chromosome condensation, RCC1. EMBO J 10, 1225-1236.[Medline]

Gietz, R. D. and Sugino, A (1988). New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74, 527-534.[Medline]

Hagan, I. M. and Hyams, J. S (1988). The use of cell division cycle mutants to investigate the control of microtubule distribution in fission yeast Schizosaccharomyces pombe. J. Cell Sci 89, 343-357.[Abstract/Free Full Text]

Hayashi, N., Yokoyama, N., Seki, T., Azuma, Y., Ohba, T. and Nishimoto, T (1995). RanBP1, a Ras-like nuclear G-protein binding to Ran/TC4, inhibits RCC1 via Ran/TC4. Mol. Gen. Genet 247, 661-669.[Medline]

Ichihara, Y. and Kurosawa, Y (1993). Construction of new T vectors for direct cloning of PCR products. Gene 130, 153-154.[Medline]

Ito, H., Fukuda, Y., Murata, K. and Kimura, A (1983). Transformation of intact S. cerevisiae cells treated with alkali cations. J. Bacteriol 153, 163-168.[Abstract/Free Full Text]

Kadowaki, T., Goldfarb, D., Spitz, L. M., Tartakoff, A. M. and Ohno, M (1993). Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily. EMBO J 12, 2929-2937.[Medline]

Klebe, C., Prinz, H., Wittinghofer, A. and Goody, R. S (1995). The kinetics mechanism of Ran-nucleotide exchange catalyzed by RCC1. Biochemistry 34, 12543-12552.[Medline]

Lee, A., Tam, R., Belhumeur, P., Dipaolo, T. and Clark, M. W (1993). Prp20, the Saccharomyces cerevisiae homolog of the regulator of chromosome condensation, RCC1, interacts with double-stranded DNA through a multi-component complex containing GTP-binding protein. J. Cell Sci 106, 287-298.[Abstract]

Lee, A., Clark, K. L., Fleischmann, M., Aebi, M. and Clark, M. W (1994). Site-directed mutagenesis of the yeast PRP20/SRM1 gene reveals distinct activity domains in the protein product. Mol. Gen. Genet 245, 32-44.[Medline]

Loeb, J. D. J., Schlenstedt, G., Pellman, D., Kornitzer, D., Silver, P. A. and Fink, G. R (1995). The yeast nuclear import receptor is required for mitosis. Proc. Nat. Acad. Sci. USA 92, 7647-7651.[Abstract/Free Full Text]

Matsumoto, T. and Beach, D (1991). Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase. Cell 66, 347-360.[Medline]

Melchior, F., Paschal, B., Evans, J. and Gerace, L (1993). Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor. J. Cell Biol 123, 1649-1659.[Abstract/Free Full Text]

Melchior, F. and Gerace, L (1995). Mechanisms of nuclear protein import. Curr. Opin. Cell Biol 7, 310-318.[Medline]

Melchior, F., Guan, T., Yokoyama, N., Nishimoto, T. and Gerace, L (1995). Hydrolysis of GTP by Ran is an early step of nuclear protein import that occurs at the cytoplasmic periphery of the nuclear pore complex. J. Cell Biol 131, 571-581.[Abstract/Free Full Text]

Moore, M. S. and Blobel, G (1993). The GTP-binding protein Ran/TC4 is required for protein import into the nucleus. Nature 365, 661-663.[Medline]

Nishitani, H., Ohtsubo, M., Yamashita, K., Iida, H., Pines, J., Yasuda, H., Shibata, Y., Hunter, T. and Nishimoto, T (1991). Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis. EMBO J 10, 1555-1564.[Medline]

Nishiwaki, H., Hayashi, N., Irie, S., Chung, D.-H., Harashima, S. and Oshima, Y (1987). Structure of the yeast HIS5 gene responsive to general control of amino acid biosynthesis. Mol. Gen. Genet 208, 159-167.[Medline]

Ninomiya-Tsuji, Nomoto, S., Yasuda, H., Reed, S. I. and Matsumoto, K (1991). Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. Proc. Nat. Acad. Sci. USA 80, 4949-4953.

Parent, S. A., Fenimore, C. M., Bostian, K (1985). Vector systems for theexpression, analysis and cloning of DNA sequences in S. cerevisiae. Yeast 1, 83-138.[Medline]

Ren, M., Drivas, G., D'Eustachio, P. and Rush, M. G (1993). Ran/TC4: a small nuclear GTP-binding protein that regulates DNA synthesis. J. Cell Biol 120, 313-323.[Abstract/Free Full Text]

Rexach, M. and Blobel, G (1996). Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins. Cell 83, 683-692.

Sazer, S. and Nurse, P (1994). A fission yeast RCC1-related protein is required for the mitosis to interphase transition. EMBO J 13, 606-615.[Medline]

Seino, H., Hisamoto, N., Uzawa, S., Sekiguchi, T. and Nishimoto, T (1992). DNA-binding domain of RCC1 protein is not essential for coupling mitosis with DNA replication. J. Cell Sci 102, 393-400.[Abstract/Free Full Text]

Schmid, S. R. and Linder, P (1992). D-E-A-D protein family of putative RNA helicases. Mol. Microbiol 6, 283-292.[Medline]

Schurmann, A., Brauers, A., Ma\247mann, S., Becker, W. and Joost, H.-G (1995). Cloning of a novel family of mammalian GTP-binding proteins(RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPase. J. Biol. Chem 270, 28982-28988.[Abstract/Free Full Text]

Tachibana, T., Imamoto, N., Seino, H., Nishimoto, T. and Yoneda, Y (1994). Loss of RCC1 leads to suppression of nuclear protein import in living cells. J. Biol. Chem 269, 24542-24545.[Abstract/Free Full Text]

Tyers, M., Tokiwa, G., Nash, R. and Futcher, B (1992). The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. EMBO J 11, 1773-1784.[Medline]

Uchida, S., Sekiguchi, T., Nishitani, H., Miyauchi, K., Ohtsubo, M. and Nishimoto, T (1990). Premature chromosome condensation is induced by a point mutation in the hamster RCC1 gene. Mol. Cell. Biol 10, 577-584.[Abstract/Free Full Text]

Winston, F., Chumley, F. and Fink, G. R (1983). Eviction and transplacement of mutant genes in yeast. Meth. Enzymol 101, 211-228.[Medline]

Yano, R., Oakes, M. L., Tabb, M. M. and Nomura, M (1994). Yeast Srp1p has homology to armadillo/plakoglobin/-catenin and participates in apparently multiple nuclear functions including the maintenance of the nucleolar structure. Proc. Nat. Acad. Sci. USA 91, 6880-6884.[Abstract/Free Full Text]

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Articles by Nakashima, N.

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				T. Sekiguchi, T. Hayano, M. Yanagida, N. Takahashi, and T. Nishimoto NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47 Nucleic Acids Res., September 11, 2006; 34(16): 4593 - 4608. [Abstract] [Full Text] [PDF]

				Y. Todaka, Y. Wang, K. Tashiro, N. Nakashima, T. Nishimoto, and T. Sekiguchi Association of the GTP-Binding Protein Gtr1p With Rpc19p, a Shared Subunit of RNA Polymerase I and III in Yeast Saccharomyces cerevisiae Genetics, August 1, 2005; 170(4): 1515 - 1524. [Abstract] [Full Text] [PDF]

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				T. Sekiguchi, E. Hirose, N. Nakashima, M. Ii, and T. Nishimoto Novel G Proteins, Rag C and Rag D, Interact with GTP-binding Proteins, Rag A and Rag B J. Biol. Chem., March 2, 2001; 276(10): 7246 - 7257. [Abstract] [Full Text] [PDF]