Occludin is a functional component of the tight junction

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by McCarthy, K. M.
	Articles by Schneeberger, E. E.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by McCarthy, K. M.
	Articles by Schneeberger, E. E.

Anderson, J. M. and Van Itallie, C. M (1995). Tight junctions and the molecular basis for regulation of paracellular permeability. Am. J. Physiol 269, 467-.

Ando-Akatsuka, Y., Saitou, M., Hirase, T., Kishi, M., Sakakibara, A., Itoh, M., Yonemura, S., Furuse, M. and Tsukita, S (1996). Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog and rat-kangaroo homologues. J. Cell Biol 133, 43-47.[Abstract/Free Full Text]

Balda, M. S., Gonzalez-Mariscal, L., Matter, K., Cereijido, M. and Anderson, J. M (1993). Assembly of the tight junction: The role of diacylglycerol. J. Cell Biol 123, 293-302.[Abstract/Free Full Text]

Birnboim, H. C. and Doly, J (1979). A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucl. Acid Res 7, 1513-1523.[Abstract/Free Full Text]

Cereijido, M., Gonzalez-Mariscal, L. and Borboa, L (1983). Occluding junctions and paracellular pathways studied in monolayers of MDCK cells. J. Exp. Biol 106, 205-215.[Abstract/Free Full Text]

Chen, C. and Okayama, H (1988). Calcium phosphate-mediated gene transfer: A highly efficient system for stably transforming cells with plasmid DNA. BioTechnology 6, 632-638.

Citi, S., Sabanay, H., Jakes, R., Geiger, B. and Kendrick-Jones, J (1988). Cingulin, a new peripheral component of tight junctions. Nature 333, 272-276.[Medline]

Citi, S (1992). Protein kinase inhibitors prevent junction dissociation induced by low extra-cellular calcium in MDCK epithelial cells. J. Cell Biol 117, 169-178.[Abstract/Free Full Text]

Citi, S. and Denisenko, N (1995). Phosphorylation of the tight junction protein cingulin and the effects of protein kinase inhibitors and activators in MDCK epithelial cells. J. Cell Sci 108, 2917-2926.[Abstract]

Claude, P (1978). Morphological factors influencing transepithelial permeability: A model for the resistance of the zonula occludens. J. Membr. Biol 39, 219-232.[Medline]

Claude, P. and Goodenough, D. A (1973). Fracture faces of zonulae occludentes from \324tight' and \324leaky' epithelia. J. Cell Biol 58, 390-400.[Abstract/Free Full Text]

DuCoeur, L. C., Wyborski, D. L. and Short, J. M (1992). Control of gene expression in eukaryotic cells using the Lac repressor system. Strategies 5, 70-72.

Fujimoto, K (1995). Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. J. Cell Sci 108, 3443-3449.[Abstract]

Furuse, M., Hirase, T., Itoh, M., Nagafuchi, A., Yonemura, S., Tsukita, S. and Tsukita, S (1993). Occludin: A novel integral membrane protein localizing at tight junctions. J. Cell Biol 123, 1777-1788.[Abstract/Free Full Text]

Furuse, M., Itoh, M., Hirase, T., Nagafuchi, A., Yonemura, S., Tsukita, S. and Tsukita, S (1994). Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J. Cell Biol 127, 1617-1626.[Abstract/Free Full Text]

Furuse, M., Fujimoto, K., Sato, N., Hirase, T., Tsukita, S. and Tsuktal, S (1996). Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures. J. Cell Sci 109, 429-435.[Abstract]

Gumbiner, B. M (1993). Breaking through the tight junction barrier. J. Cell Biol 123, 1631-1633.[Free Full Text]

Gumbiner, B. M (1996). Cell adhesion: The molecular basis of tissue architecture and morphogenesis. Cell 84, 345-357.[Medline]

Gumbiner, B., Stevenson, B. and Grimaldi, A (1988). The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J. Cell Biol 107, 1575-1587.[Abstract/Free Full Text]

Gumbiner, B., Lowenkopf, T. and Apatira, D (1991). Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc. Nat. Acad. Sci. USA 88, 3460-3464.[Abstract/Free Full Text]

Howarth, A. G., Singer, K. L. and Stevenson, B. R (1994). Analysis of the distribution and phosphorylation state of ZO-1 in MDCK and nonepithelial cells. J. Membr. Biol 137, 261-270.[Medline]

Jesaitis, L. A. and Goodenough, D. A (1994). Molecular characterization and tissue distribution of ZO-2, a tight junction protein homologous to ZO-1 and the Drosophila discs-large tumor suppressor protein. J. Cell Biol 124, 949-961.[Abstract/Free Full Text]

Laemmli, U. K (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.[Medline]

Lynch, R. D., Tkachuk, L. J., Ji, X., Rabito, C. A. and Schneeberger, E. E (1993). Depleting cell cholesterol alters calcium-induced assembly of tight junctions by monolayers of MDCK cells. Eur. J. Cell Biol 60, 21-30.[Medline]

Lynch, R. D., Tkachuk, L. J., McCormack, J. M., McCarthy, K. M., Rogers, R. A. and Schneeberger, E. E (1995). Basolateral but not apical application of protease results in a rapid rise of transepithelial electrical resistance and formation of aberrant tight junction strands in MDCK cells. Eur. J. Cell Biol 66, 257-267.[Medline]

Madara, J. L. and Dharmsathaphorn, K (1985). Occluding junction structure-function relationships in a cultured epithelial monolayer. J. Cell Biol 101, 2124-2133.[Abstract/Free Full Text]

Martinez-Paloma, A. and Erlij, D (1975). Structure of tight junctions in epithelia with different permeability. Proc. Nat. Acad. Sci. USA 72, 4487-4491.[Abstract/Free Full Text]

Nelson, W. J (1992). Regulation of cell surface polarity from bacteria to mammals. Science 258, 948-955.[Abstract/Free Full Text]

Rochat, T., Casale, J., Hunninghake, G. W. and Peterson, M. W (1988). Neutrophil cathepsin G increases permeability of cultured type II pneumocytes. Am. J. Physiol 255, 603-.

Schneeberger, E. E. and Karnovsky, M. J (1976). Substructure of intercellular junctions in freeze-fractured alveolar-capillary membranes of mouse lung. Circ. Res 38, 404-411.[Abstract/Free Full Text]

Schneeberger, E. E., Walters, D. V. and Olver, R. E (1978). Development of intercellular junctions in the pulmonary epithelium of the foetal lamb. J. Cell Sci 32, 307-324.[Abstract]

Schneeberger, E. E. and Lynch, R. D (1992). Structure, function and regulation of cellular tight junctions. Am. J. Physiol 262, 647-.

Stevenson, B. R., Siliciano, J. D., Mooseker, J. D. and Goodenough, D. A (1986). Identification of ZO-1: A high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol 103, 755-766.[Abstract/Free Full Text]

Stevenson, B. R., Anderson, J. M., Goodenough, D. A. and Mooseker, M. S (1988). Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial electrical resistance. J. Cell Biol 107, 2401-2408.[Abstract/Free Full Text]

Towbin, H., Staehelin, T. and Gordon, J (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc. Nat. Acad. Sci. USA 76, 4350-4354.[Abstract/Free Full Text]

Tsukita, S., Itoh, M., Nagafuchi, A., Yonemura, S. and Tsukita, S (1993). Submembranous junctional plaque proteins include potential tumor suppressor molecules. J. Cell Biol 123, 1049-1053.[Free Full Text]

Zhong, Y., Saitoh, T., Minase, T., Sawada, N., Enomoto, K. and Mori, M (1993). Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2. J. Cell Biol 120, 477-483.[Abstract/Free Full Text]

This article has been cited by other articles:

S. Angelow, R. Ahlstrom, and A. S. L. Yu
Biology of claudins
Am J Physiol Renal Physiol, October 1, 2008; 295(4): F867 - F876.
[Abstract] [Full Text] [PDF]

B. E. Phillips, L. Cancel, J. M. Tarbell, and D. A. Antonetti
Occludin Independently Regulates Permeability under Hydrostatic Pressure and Cell Division in Retinal Pigment Epithelial Cells
Invest. Ophthalmol. Vis. Sci., June 1, 2008; 49(6): 2568 - 2576.
[Abstract] [Full Text] [PDF]

H. Chasiotis and S. P. Kelly
Occludin immunolocalization and protein expression in goldfish
J. Exp. Biol., May 15, 2008; 211(10): 1524 - 1534.
[Abstract] [Full Text] [PDF]

V. K. Sidhaye, K. S. Schweitzer, M. J. Caterina, L. Shimoda, and L. S. King
Shear stress regulates aquaporin-5 and airway epithelial barrier function
PNAS, March 4, 2008; 105(9): 3345 - 3350.
[Abstract] [Full Text] [PDF]

K. Dokladny, D. Ye, J. C. Kennedy, P. L. Moseley, and T. Y. Ma
Cellular and Molecular Mechanisms of Heat Stress-Induced Up-Regulation of Occludin Protein Expression: Regulatory Role of Heat Shock Factor-1
Am. J. Pathol., March 1, 2008; 172(3): 659 - 670.
[Abstract] [Full Text] [PDF]

X. Sun, H. Yang, K. Nose, S. Nose, E. Q. Haxhija, H. Koga, Y. Feng, and D. H. Teitelbaum
Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition
Am J Physiol Gastrointest Liver Physiol, January 1, 2008; 294(1): G139 - G147.
[Abstract] [Full Text] [PDF]

L. A. Moser, M. Carter, and S. Schultz-Cherry
Astrovirus Increases Epithelial Barrier Permeability Independently of Viral Replication
J. Virol., November 1, 2007; 81(21): 11937 - 11945.
[Abstract] [Full Text] [PDF]

Y. Tokunaga, T. Kojima, M. Osanai, M. Murata, H. Chiba, H. Tobioka, and N. Sawada
A Novel Monoclonal Antibody Against the Second Extracellular Loop of Occludin Disrupts Epithelial Cell Polarity
J. Histochem. Cytochem., July 1, 2007; 55(7): 735 - 744.
[Abstract] [Full Text] [PDF]

G. I. Gorodeski
Estrogen Decrease in Tight Junctional Resistance Involves Matrix-Metalloproteinase-7-Mediated Remodeling of Occludin
Endocrinology, January 1, 2007; 148(1): 218 - 231.
[Abstract] [Full Text] [PDF]

G. Abuazza, A. Becker, S. S. Williams, S. Chakravarty, H.-T. Truong, F. Lin, and M. Baum
Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins
Am J Physiol Renal Physiol, December 1, 2006; 291(6): F1132 - F1141.
[Abstract] [Full Text] [PDF]

C. Forster, J. Waschke, M. Burek, J. Leers, and D. Drenckhahn
Glucocorticoid effects on mouse microvascular endothelial barrier permeability are brain specific
J. Physiol., June 1, 2006; 573(2): 413 - 425.
[Abstract] [Full Text] [PDF]

L. Shen, E. D. Black, E. D. Witkowski, W. I. Lencer, V. Guerriero, E. E. Schneeberger, and J. R. Turner
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure
J. Cell Sci., May 15, 2006; 119(10): 2095 - 2106.
[Abstract] [Full Text] [PDF]

K. Dokladny, P. L. Moseley, and T. Y. Ma
Physiologically relevant increase in temperature causes an increase in intestinal epithelial tight junction permeability
Am J Physiol Gastrointest Liver Physiol, February 1, 2006; 290(2): G204 - G212.
[Abstract] [Full Text] [PDF]

R. S. Everett, M. K. Vanhook, N. Barozzi, I. Toth, and L. G. Johnson
Specific Modulation of Airway Epithelial Tight Junctions by Apical Application of an Occludin Peptide
Mol. Pharmacol., February 1, 2006; 69(2): 492 - 500.
[Abstract] [Full Text] [PDF]

L. DeMaio, M. Rouhanizadeh, S. Reddy, A. Sevanian, J. Hwang, and T. K. Hsiai
Oxidized phospholipids mediate occludin expression and phosphorylation in vascular endothelial cells
Am J Physiol Heart Circ Physiol, February 1, 2006; 290(2): H674 - H683.
[Abstract] [Full Text] [PDF]

J. M. Mullin, J. M. Leatherman, M. C. Valenzano, E. R. Huerta, J. Verrechio, D. M. Smith, K. Snetselaar, M. Liu, M. K. Francis, and C. Sell
Ras Mutation Impairs Epithelial Barrier Function to a Wide Range of Nonelectrolytes
Mol. Biol. Cell, December 1, 2005; 16(12): 5538 - 5550.
[Abstract] [Full Text] [PDF]

M. E. Osler, M. S. Chang, and D. M. Bader
Bves modulates epithelial integrity through an interaction at the tight junction
J. Cell Sci., October 15, 2005; 118(20): 4667 - 4678.
[Abstract] [Full Text] [PDF]

F. Carrozzino, P. Soulie, D. Huber, N. Mensi, L. Orci, A. Cano, E. Feraille, and R. Montesano
Inducible expression of Snail selectively increases paracellular ion permeability and differentially modulates tight junction proteins
Am J Physiol Cell Physiol, October 1, 2005; 289(4): C1002 - C1014.
[Abstract] [Full Text] [PDF]

L. Shen and J. R. Turner
Actin Depolymerization Disrupts Tight Junctions via Caveolae-mediated Endocytosis
Mol. Biol. Cell, September 1, 2005; 16(9): 3919 - 3936.
[Abstract] [Full Text] [PDF]

M. M. Walsh-Reitz, E. F. Huang, M. W. Musch, E. B. Chang, T. E. Martin, S. Kartha, and F. G. Toback
AMP-18 protects barrier function of colonic epithelial cells: role of tight junction proteins
Am J Physiol Gastrointest Liver Physiol, July 1, 2005; 289(1): G163 - G171.
[Abstract] [Full Text] [PDF]

B. T. Hawkins and T. P. Davis
The Blood-Brain Barrier/Neurovascular Unit in Health and Disease
Pharmacol. Rev., June 1, 2005; 57(2): 173 - 185.
[Abstract] [Full Text] [PDF]

X. Guo, J. N. Rao, L. Liu, T. Zou, K. M. Keledjian, D. Boneva, B. S. Marasa, and J.-Y. Wang
Polyamines are necessary for synthesis and stability of occludin protein in intestinal epithelial cells
Am J Physiol Gastrointest Liver Physiol, June 1, 2005; 288(6): G1159 - G1169.
[Abstract] [Full Text] [PDF]

A. S. L. Yu, K. M. McCarthy, S. A. Francis, J. M. McCormack, J. Lai, R. A. Rogers, R. D. Lynch, and E. E. Schneeberger
Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells
Am J Physiol Cell Physiol, June 1, 2005; 288(6): C1231 - C1241.
[Abstract] [Full Text] [PDF]

M. Kondoh, A. Masuyama, A. Takahashi, N. Asano, H. Mizuguchi, N. Koizumi, M. Fujii, T. Hayakawa, Y. Horiguchi, and Y. Watanbe
A Novel Strategy for the Enhancement of Drug Absorption Using a Claudin Modulator
Mol. Pharmacol., March 1, 2005; 67(3): 749 - 756.
[Abstract] [Full Text] [PDF]

K. J. Roux, S. A. Amici, B. S. Fletcher, and L. Notterpek
Modulation of Epithelial Morphology, Monolayer Permeability, and Cell Migration by Growth Arrest Specific 3/Peripheral Myelin Protein 22
Mol. Biol. Cell, March 1, 2005; 16(3): 1142 - 1151.
[Abstract] [Full Text] [PDF]

R. Zeng, X. Li, and G. I. Gorodeski
Estrogen Abrogates Transcervical Tight Junctional Resistance by Acceleration of Occludin Modulation
J. Clin. Endocrinol. Metab., October 1, 2004; 89(10): 5145 - 5155.
[Abstract] [Full Text] [PDF]

D. D. Mruk and C. Y. Cheng
Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis
Endocr. Rev., October 1, 2004; 25(5): 747 - 806.
[Abstract] [Full Text] [PDF]

M. Cereijido, R. G. Contreras, and L. Shoshani
Cell Adhesion, Polarity, and Epithelia in the Dawn of Metazoans
Physiol Rev, October 1, 2004; 84(4): 1229 - 1262.
[Abstract] [Full Text] [PDF]

S. Roig-Perez, F. Guardiola, M. Moreto, and R. Ferrer
Lipid peroxidation induced by DHA enrichment modifies paracellular permeability in Caco-2 cells: protective role of taurine
J. Lipid Res., August 1, 2004; 45(8): 1418 - 1428.
[Abstract] [Full Text] [PDF]

D. Talavera, A. M. Castillo, M. C. Dominguez, A. E. Gutierrez, and I. Meza
IL8 release, tight junction and cytoskeleton dynamic reorganization conducive to permeability increase are induced by dengue virus infection of microvascular endothelial monolayers
J. Gen. Virol., July 1, 2004; 85(7): 1801 - 1813.
[Abstract] [Full Text] [PDF]

Y. Zhu, J. Maric, M. Nilsson, M. Brannstrom, P.-O. Janson, and K. Sundfeldt
Formation and Barrier Function of Tight Junctions in Human Ovarian Surface Epithelium
Biol Reprod, July 1, 2004; 71(1): 53 - 59.
[Abstract] [Full Text] [PDF]

E. E. Schneeberger and R. D. Lynch
The tight junction: a multifunctional complex
Am J Physiol Cell Physiol, June 1, 2004; 286(6): C1213 - C1228.
[Abstract] [Full Text] [PDF]

M. K. Schuster, B. Schmierer, A. Shkumatava, and K. Kuchler
Activin A and Follicle-Stimulating Hormone Control Tight Junctions in Avian Granulosa Cells by Regulating Occludin Expression
Biol Reprod, May 1, 2004; 70(5): 1493 - 1499.
[Abstract] [Full Text] [PDF]

C. Barmeyer, M. Harren, H. Schmitz, U. Heinzel-Pleines, J. Mankertz, U. Seidler, I. Horak, B. Wiedenmann, M. Fromm, and J. D. Schulzke
Mechanisms of diarrhea in the interleukin-2-deficient mouse model of colonic inflammation
Am J Physiol Gastrointest Liver Physiol, February 1, 2004; 286(2): G244 - G252.
[Abstract] [Full Text] [PDF]

T. N. Meyer, J. Hunt, C. Schwesinger, and B. M. Denker
G{alpha}12 regulates epithelial cell junctions through Src tyrosine kinases
Am J Physiol Cell Physiol, November 1, 2003; 285(5): C1281 - C1293.
[Abstract] [Full Text] [PDF]

T. Abe, E. Sugano, Y. Saigo, and M. Tamai
Interleukin-1{beta} and Barrier Function of Retinal Pigment Epithelial Cells (ARPE-19): Aberrant Expression of Junctional Complex Molecules
Invest. Ophthalmol. Vis. Sci., September 1, 2003; 44(9): 4097 - 4104.
[Abstract] [Full Text] [PDF]

A. K. Rajasekaran and S. A. Rajasekaran
Role of Na-K-ATPase in the assembly of tight junctions
Am J Physiol Renal Physiol, September 1, 2003; 285(3): F388 - F396.
[Abstract] [Full Text] [PDF]

M. M. Choe, P. H. S. Sporn, and M. A. Swartz
An in vitro airway wall model of remodeling
Am J Physiol Lung Cell Mol Physiol, August 1, 2003; 285(2): L427 - L433.
[Abstract] [Full Text] [PDF]

P. Guo, A. M. Weinstein, and S. Weinbaum
A dual-pathway ultrastructural model for the tight junction of rat proximal tubule epithelium
Am J Physiol Renal Physiol, August 1, 2003; 285(2): F241 - F257.
[Abstract] [Full Text] [PDF]

E. E. Schneeberger
Claudins form ion-selective channels in the paracellular pathway. Focus on "Claudin extracellular domains determine paracellular charge selectively and resistance but not tight junction fibril architecture"
Am J Physiol Cell Physiol, June 1, 2003; 284(6): C1331 - C1333.
[Full Text] [PDF]

O. R. Colegio, C. V. Itallie, C. Rahner, and J. M. Anderson
Claudin extracellular domains determine paracellular charge selectivity and resistance but not tight junction fibril architecture
Am J Physiol Cell Physiol, June 1, 2003; 284(6): C1346 - C1354.
[Abstract] [Full Text] [PDF]

S. A. Rajasekaran, J. Hu, J. Gopal, R. Gallemore, S. Ryazantsev, D. Bok, and A. K. Rajasekaran
Na,K-ATPase inhibition alters tight junction structure and permeability in human retinal pigment epithelial cells
Am J Physiol Cell Physiol, June 1, 2003; 284(6): C1497 - C1507.
[Abstract] [Full Text] [PDF]

A. S. L. Yu, A. H. Enck, W. I. Lencer, and E. E. Schneeberger
Claudin-8 Expression in Madin-Darby Canine Kidney Cells Augments the Paracellular Barrier to Cation Permeation
J. Biol. Chem., May 2, 2003; 278(19): 17350 - 17359.
[Abstract] [Full Text] [PDF]

W.-Y. Lui, D. Mruk, W. M Lee, and C. Y. Cheng
Sertoli Cell Tight Junction Dynamics: Their Regulation During Spermatogenesis
Biol Reprod, April 1, 2003; 68(4): 1087 - 1097.
[Abstract] [Full Text] [PDF]

S. Amasheh, N. Meiri, A. H. Gitter, T. Schoneberg, J. Mankertz, J. D. Schulzke, and M. Fromm
Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells
J. Cell Sci., March 14, 2003; 115(24): 4969 - 4976.
[Abstract] [Full Text] [PDF]

J Berkes, V K Viswanathan, S D Savkovic, and G Hecht
Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation
Gut, March 1, 2003; 52(3): 439 - 451.
[Abstract] [Full Text] [PDF]

S. Peng, C. Rahner, and L. J. Rizzolo
Apical and Basal Regulation of the Permeability of the Retinal Pigment Epithelium
Invest. Ophthalmol. Vis. Sci., February 1, 2003; 44(2): 808 - 817.
[Abstract] [Full Text] [PDF]

L. L. Mitic, V. M. Unger, and J. M. Anderson
Expression, solubilization, and biochemical characterization of the tight junction transmembrane protein claudin-4
Protein Sci., February 1, 2003; 12(2): 218 - 227.
[Abstract] [Full Text] [PDF]

S. Poliak, S. Matlis, C. Ullmer, S. S. Scherer, and E. Peles
Distinct claudins and associated PDZ proteins form different autotypic tight junctions in myelinating Schwann cells
J. Cell Biol., October 28, 2002; 159(2): 361 - 372.
[Abstract] [Full Text] [PDF]

J. D. Huber, V. S. Hau, L. Borg, C. R. Campos, R. D. Egleton, and T. P. Davis
Blood-brain barrier tight junctions are altered during a 72-h exposure to lambda -carrageenan-induced inflammatory pain
Am J Physiol Heart Circ Physiol, October 1, 2002; 283(4): H1531 - H1537.
[Abstract] [Full Text] [PDF]

R. Quigley and M. Baum
Developmental changes in rabbit proximal straight tubule paracellular permeability
Am J Physiol Renal Physiol, September 1, 2002; 283(3): F525 - F531.
[Abstract] [Full Text] [PDF]

M. Jin, E. Barron, S. He, S. J. Ryan, and D. R. Hinton
Regulation of RPE Intercellular Junction Integrity and Function by Hepatocyte Growth Factor
Invest. Ophthalmol. Vis. Sci., August 1, 2002; 43(8): 2782 - 2790.
[Abstract] [Full Text] [PDF]

Y.-H. Chen, Q. Lu, D. A. Goodenough, and B. Jeansonne
Nonreceptor Tyrosine Kinase c-Yes Interacts with Occludin during Tight Junction Formation in Canine Kidney Epithelial Cells
Mol. Biol. Cell, April 1, 2002; 13(4): 1227 - 1237.
[Abstract] [Full Text] [PDF]

M. Furuse, M. Hata, K. Furuse, Y. Yoshida, A. Haratake, Y. Sugitani, T. Noda, A. Kubo, and S. Tsukita
Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1-deficient mice
J. Cell Biol., March 18, 2002; 156(6): 1099 - 1111.
[Abstract] [Full Text] [PDF]

				B. E. Phillips, L. Cancel, J. M. Tarbell, and D. A. Antonetti Occludin Independently Regulates Permeability under Hydrostatic Pressure and Cell Division in Retinal Pigment Epithelial Cells Invest. Ophthalmol. Vis. Sci., June 1, 2008; 49(6): 2568 - 2576. [Abstract] [Full Text] [PDF]

				H. Chasiotis and S. P. Kelly Occludin immunolocalization and protein expression in goldfish J. Exp. Biol., May 15, 2008; 211(10): 1524 - 1534. [Abstract] [Full Text] [PDF]

				V. K. Sidhaye, K. S. Schweitzer, M. J. Caterina, L. Shimoda, and L. S. King Shear stress regulates aquaporin-5 and airway epithelial barrier function PNAS, March 4, 2008; 105(9): 3345 - 3350. [Abstract] [Full Text] [PDF]

				K. Dokladny, D. Ye, J. C. Kennedy, P. L. Moseley, and T. Y. Ma Cellular and Molecular Mechanisms of Heat Stress-Induced Up-Regulation of Occludin Protein Expression: Regulatory Role of Heat Shock Factor-1 Am. J. Pathol., March 1, 2008; 172(3): 659 - 670. [Abstract] [Full Text] [PDF]

				X. Sun, H. Yang, K. Nose, S. Nose, E. Q. Haxhija, H. Koga, Y. Feng, and D. H. Teitelbaum Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition Am J Physiol Gastrointest Liver Physiol, January 1, 2008; 294(1): G139 - G147. [Abstract] [Full Text] [PDF]

				L. A. Moser, M. Carter, and S. Schultz-Cherry Astrovirus Increases Epithelial Barrier Permeability Independently of Viral Replication J. Virol., November 1, 2007; 81(21): 11937 - 11945. [Abstract] [Full Text] [PDF]

				Y. Tokunaga, T. Kojima, M. Osanai, M. Murata, H. Chiba, H. Tobioka, and N. Sawada A Novel Monoclonal Antibody Against the Second Extracellular Loop of Occludin Disrupts Epithelial Cell Polarity J. Histochem. Cytochem., July 1, 2007; 55(7): 735 - 744. [Abstract] [Full Text] [PDF]

				G. I. Gorodeski Estrogen Decrease in Tight Junctional Resistance Involves Matrix-Metalloproteinase-7-Mediated Remodeling of Occludin Endocrinology, January 1, 2007; 148(1): 218 - 231. [Abstract] [Full Text] [PDF]

				G. Abuazza, A. Becker, S. S. Williams, S. Chakravarty, H.-T. Truong, F. Lin, and M. Baum Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins Am J Physiol Renal Physiol, December 1, 2006; 291(6): F1132 - F1141. [Abstract] [Full Text] [PDF]

				C. Forster, J. Waschke, M. Burek, J. Leers, and D. Drenckhahn Glucocorticoid effects on mouse microvascular endothelial barrier permeability are brain specific J. Physiol., June 1, 2006; 573(2): 413 - 425. [Abstract] [Full Text] [PDF]

				L. Shen, E. D. Black, E. D. Witkowski, W. I. Lencer, V. Guerriero, E. E. Schneeberger, and J. R. Turner Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure J. Cell Sci., May 15, 2006; 119(10): 2095 - 2106. [Abstract] [Full Text] [PDF]

				K. Dokladny, P. L. Moseley, and T. Y. Ma Physiologically relevant increase in temperature causes an increase in intestinal epithelial tight junction permeability Am J Physiol Gastrointest Liver Physiol, February 1, 2006; 290(2): G204 - G212. [Abstract] [Full Text] [PDF]

				R. S. Everett, M. K. Vanhook, N. Barozzi, I. Toth, and L. G. Johnson Specific Modulation of Airway Epithelial Tight Junctions by Apical Application of an Occludin Peptide Mol. Pharmacol., February 1, 2006; 69(2): 492 - 500. [Abstract] [Full Text] [PDF]

				L. DeMaio, M. Rouhanizadeh, S. Reddy, A. Sevanian, J. Hwang, and T. K. Hsiai Oxidized phospholipids mediate occludin expression and phosphorylation in vascular endothelial cells Am J Physiol Heart Circ Physiol, February 1, 2006; 290(2): H674 - H683. [Abstract] [Full Text] [PDF]

				J. M. Mullin, J. M. Leatherman, M. C. Valenzano, E. R. Huerta, J. Verrechio, D. M. Smith, K. Snetselaar, M. Liu, M. K. Francis, and C. Sell Ras Mutation Impairs Epithelial Barrier Function to a Wide Range of Nonelectrolytes Mol. Biol. Cell, December 1, 2005; 16(12): 5538 - 5550. [Abstract] [Full Text] [PDF]

				M. E. Osler, M. S. Chang, and D. M. Bader Bves modulates epithelial integrity through an interaction at the tight junction J. Cell Sci., October 15, 2005; 118(20): 4667 - 4678. [Abstract] [Full Text] [PDF]

				F. Carrozzino, P. Soulie, D. Huber, N. Mensi, L. Orci, A. Cano, E. Feraille, and R. Montesano Inducible expression of Snail selectively increases paracellular ion permeability and differentially modulates tight junction proteins Am J Physiol Cell Physiol, October 1, 2005; 289(4): C1002 - C1014. [Abstract] [Full Text] [PDF]

				L. Shen and J. R. Turner Actin Depolymerization Disrupts Tight Junctions via Caveolae-mediated Endocytosis Mol. Biol. Cell, September 1, 2005; 16(9): 3919 - 3936. [Abstract] [Full Text] [PDF]

				M. M. Walsh-Reitz, E. F. Huang, M. W. Musch, E. B. Chang, T. E. Martin, S. Kartha, and F. G. Toback AMP-18 protects barrier function of colonic epithelial cells: role of tight junction proteins Am J Physiol Gastrointest Liver Physiol, July 1, 2005; 289(1): G163 - G171. [Abstract] [Full Text] [PDF]

				B. T. Hawkins and T. P. Davis The Blood-Brain Barrier/Neurovascular Unit in Health and Disease Pharmacol. Rev., June 1, 2005; 57(2): 173 - 185. [Abstract] [Full Text] [PDF]

				X. Guo, J. N. Rao, L. Liu, T. Zou, K. M. Keledjian, D. Boneva, B. S. Marasa, and J.-Y. Wang Polyamines are necessary for synthesis and stability of occludin protein in intestinal epithelial cells Am J Physiol Gastrointest Liver Physiol, June 1, 2005; 288(6): G1159 - G1169. [Abstract] [Full Text] [PDF]

				A. S. L. Yu, K. M. McCarthy, S. A. Francis, J. M. McCormack, J. Lai, R. A. Rogers, R. D. Lynch, and E. E. Schneeberger Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells Am J Physiol Cell Physiol, June 1, 2005; 288(6): C1231 - C1241. [Abstract] [Full Text] [PDF]

				M. Kondoh, A. Masuyama, A. Takahashi, N. Asano, H. Mizuguchi, N. Koizumi, M. Fujii, T. Hayakawa, Y. Horiguchi, and Y. Watanbe A Novel Strategy for the Enhancement of Drug Absorption Using a Claudin Modulator Mol. Pharmacol., March 1, 2005; 67(3): 749 - 756. [Abstract] [Full Text] [PDF]

				K. J. Roux, S. A. Amici, B. S. Fletcher, and L. Notterpek Modulation of Epithelial Morphology, Monolayer Permeability, and Cell Migration by Growth Arrest Specific 3/Peripheral Myelin Protein 22 Mol. Biol. Cell, March 1, 2005; 16(3): 1142 - 1151. [Abstract] [Full Text] [PDF]

				R. Zeng, X. Li, and G. I. Gorodeski Estrogen Abrogates Transcervical Tight Junctional Resistance by Acceleration of Occludin Modulation J. Clin. Endocrinol. Metab., October 1, 2004; 89(10): 5145 - 5155. [Abstract] [Full Text] [PDF]

				D. D. Mruk and C. Y. Cheng Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their Significance in Germ Cell Movement in the Seminiferous Epithelium during Spermatogenesis Endocr. Rev., October 1, 2004; 25(5): 747 - 806. [Abstract] [Full Text] [PDF]

				M. Cereijido, R. G. Contreras, and L. Shoshani Cell Adhesion, Polarity, and Epithelia in the Dawn of Metazoans Physiol Rev, October 1, 2004; 84(4): 1229 - 1262. [Abstract] [Full Text] [PDF]

				S. Roig-Perez, F. Guardiola, M. Moreto, and R. Ferrer Lipid peroxidation induced by DHA enrichment modifies paracellular permeability in Caco-2 cells: protective role of taurine J. Lipid Res., August 1, 2004; 45(8): 1418 - 1428. [Abstract] [Full Text] [PDF]

				D. Talavera, A. M. Castillo, M. C. Dominguez, A. E. Gutierrez, and I. Meza IL8 release, tight junction and cytoskeleton dynamic reorganization conducive to permeability increase are induced by dengue virus infection of microvascular endothelial monolayers J. Gen. Virol., July 1, 2004; 85(7): 1801 - 1813. [Abstract] [Full Text] [PDF]

				Y. Zhu, J. Maric, M. Nilsson, M. Brannstrom, P.-O. Janson, and K. Sundfeldt Formation and Barrier Function of Tight Junctions in Human Ovarian Surface Epithelium Biol Reprod, July 1, 2004; 71(1): 53 - 59. [Abstract] [Full Text] [PDF]