Identification of a molecular chaperone in the eukaryotic flagellum and its localization to the site of microtubule assembly

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Ahmad, S., Ahuja, R., Venner, T. and Gupta, R (1990). Identification of a protein altered in mutants resistant to microtubule inhibitors as a member of the major heat shock protein (hsp70) family. Mol. Cell. Biol 10, 5160-5165.[Abstract/Free Full Text]

Beckman, R., Mizzen, L. and Welch, W (1990). Interaction of Hsp70 with newly synthesized proteins: implications for protein folding and assembly. Science 248, 850-854.[Abstract/Free Full Text]

Binder, L., Dentler, W. and Rosenbaum, J (1975). Assembly of chick brain tubulin onto flagellar microtubules from Chlamydomonas and sea urchin sperm. Proc. Nat. Acad. Sci. USA 72, 1122-1126.[Abstract/Free Full Text]

Burrows, J., Liggit, P. and Baker, E (1994). Heat shock and deflagellation induce a short-lived HSP70 mRNA in Chlamydomonas. Mol. Biol. Cell 5, 218-.

Clarke, C., Cheng, K., Frey, A., Stein, R., Hinds, P. and Levine, A (1988). Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP. Mol. Cell. Biol 8, 1206-1215.[Abstract/Free Full Text]

Craig, E (1989). Essential roles of 70kDa heat inducible proteins. BioEssays 11, 48-52.[Medline]

Craig, E., Gambill, B. and Nelson, R (1993). Heat shock proteins: molecular chaperones of protein biogenesis. Microbiol. Rev 57, 402-414.[Abstract/Free Full Text]

Dentler, W. and Rosenbaum, J (1977). Flagellar elongation and shortening in Chlamydomonas: III. Structures attached to the tips of flagellar microtubules and their relationship to the directionality of flagellar microtubule assembly. J. Cell Biol 74, 747-759.[Abstract/Free Full Text]

Fox, L., Sawin, K. and Sale, W (1994). Kinesin-related proteins in eukaryotic flagellum. J. Cell Sci 107, 1545-1550.[Abstract]

Gao, Y., Thomas, J., Chow, R., Lee, G.-H. and Cowan, N (1992). A cytoplasmic chaperonin that catalyzes B-actin folding. Cell 69, 1043-1050.[Medline]

Gao, Y., Vainberg, I., Chow, R. and Cowan, N (1993). Two cofactors and cytoplasmic chaperonin are required for the folding of alpha-and beta-tubulin. Mol. Cell. Biol 13, 2478-2485.[Abstract/Free Full Text]

Georgopoulos, C. and Welch, W (1993). Role of the major heat shock proteins as molecular chaperones. Annu. Rev. Cell Biol 9, 601-634.

Green, L. and Liem, R (1989). Beta-internexin is a microtubule-asociated protein identical to the 70-kDa heat-shock cognate protein and the clathrin uncoating ATPase. J. Biol. Chem 264, 15210-15215.[Abstract/Free Full Text]

Gromoff, E., Treier, U. and Beck, C (1989). Three light-inducible heat shock genes of Chlamydomonas reinhardtii. Mol. Cell. Biol 9, 3911-3918.[Abstract/Free Full Text]

Gupta, R (1983). Podophyllotoxin-resistant mutants of Chinese hamster ovary cells: cross-resistance studies with various microtubule inhibitors and podophyllotoxin analogues. Cancer Res 43, 505-512.[Abstract/Free Full Text]

Guttman, S., Glover, C., Allis, C. and Gorovsky, M (1980). Heat shock, decilliation and release from anoxia induce the synthesis of the same set of polypeptides in starved T. pyriformis. Cell 22, 299-307.[Medline]

Johnson, K. and Rosenbaum, J (1992). Polarity of flagellar assembly in Chlamydomonas. J. Cell Biol 119, 1605-1611.[Abstract/Free Full Text]

Kozminski, K., Johnson, K., Forscher, P. and Rosenbaum, J (1993). A motility in the eukaryotic flagellum unrelated to flagellar beating. Proc. Nat. Acad. Sci. USA 90, 5519-5523.[Abstract/Free Full Text]

Kurtz, S., Rossi, J., Peteko, L. and Lindquist, S (1986). An ancient developmental induction: heat shock proteins induced in sporulation and oogenesis. Science 231, 1154-1157.[Abstract/Free Full Text]

LeDizet, M. and Piperno, G (1986). Cytoplasmic microtubules containing acetylated alpha-tubulin in Chlamydomonas reinhardtii : spatial arrangement and properties. J. Cell Biol 103, 13-22.[Abstract/Free Full Text]

Lewis, M. and Pelham, H (1985). Involvement of ATP in the nuclear and nucleolar functions of the 70 kd heat shock protein. EMBO J 4, 3137-3143.[Medline]

Lewis, V., Hynes, G., Zheng, D., Saibil, H. and Willison, K (1992). T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol. Nature 358, 249-252.[Medline]

Marchesi, V. and Ngo, N (1993). In vitro assembly of multiprotein complexes containing alpha, beta and gamma tubulin, heat shock protein hsp70, and elongation factor 1 alpha. Proc. Nat. Acad. Sci.USA 90, 3028-3032.[Abstract/Free Full Text]

May, G. and Rosenbaum, J (1980). Induction and synthesis of heat shock proteins in Chlamydomonas reinhardtii. J. Cell Biol 87, 272-.

Perret, E., Moudjou, M., Geraud, M., Derancourt, J., Soyer-Gobillard, M.-O. and Bornens, M (1995). Identification of an HSP70-related protein associated with the centrosome from dinoflagellates to human cells. J. Cell Sci 108, 711-725.[Abstract]

Rattner, J (1991). Hsp70 is localized to the centrosome of dividing HeLa cells. Exp. Cell Res 195, 110-113.[Medline]

Rose, M., Misra, L. and Vogel, J (1989). Kar2, a karyogamy gene, is the yeast homolog of the mammalian BiP/GRP78 gene. Cell 57, 1211-1221.[Medline]

Sanchez, C., Padilla, R., Paciucci, R., Zabala, J. and Avila, J (1994). Binding of heat-shock protein (hsp70) to tubulin. Arch. Biochem. Biophys 310, 428-432.[Medline]

Suprenant, K. and Dentler, W (1988). Release of intact microtubule-capping structures from Tetrahymena cilia. J. Cell Biol 107, 2259-2269.[Abstract/Free Full Text]

Ungewickell, E (1985). The 70-kd mammalian heat shock proteins are structurally and functionally related to the uncoating protein that releases clathrin triskelia from coated vesicles. EMBO J 4, 3385-3391.[Medline]

Ursic, D. and Culbertson, M (1991). The yeast homologue to mouse TCP-1 affects microtubule mediated processes. Mol. Cell. Biol 11, 2629-2640.[Abstract/Free Full Text]

Ursic, D., Sedbrook, J., Himmel, K. and Culbertson,M (1994). The essential yeast TCP-1 protein affects actin and microtubules. Mol. Biol. Cell 5, 1065-1080.[Abstract]

Wang, W., Suprenant, K. and Dentler, W (1993). Reversible association of a 97-kDa protein complex found at the tips of ciliary microtubules with in vitro assembled microtubules. J. Biol. Chem 268, 24796-24807.[Abstract/Free Full Text]

Watanabe, T. and Flavin, M (1976). Nucleotide-metabolizing enzymes in Chlamydomonas flagella. J. Biol. Chem 251, 182-192.[Abstract/Free Full Text]

Witman, G (1975). The site of in vivo assembly of flagellar microtubules. Ann. NY Acad. Sci 253, 178-191.[Medline]

Witman, G (1986). Isolation of Chlamydomonas flagella and flagellar axonemes. Meth. Enzymol 134, 280-290.[Medline]

Witman, G., Carlson, K., Berliner, J. and Rosenbaum, J (1972). Chlamydomonas flagella: isolation and electrophoretic analysis of microtubules, matrix, membranes, and mastigonemes. J. Cell Biol 54, 507-539.[Abstract/Free Full Text]

Yaffe, M., Farr, G., Miklos, D., Horwich, A., Sternlicht, M. and Sternlicht, H (1992). TCP1 complex is a molecular chaperone in tubulin biogenesis. Nature 358, 245-248.[Medline]

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Articles by Bloch, M. A.

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				E. Takaki, M. Fujimoto, T. Nakahari, S. Yonemura, Y. Miyata, N. Hayashida, K. Yamamoto, R. B. Vallee, T. Mikuriya, K. Sugahara, et al. Heat Shock Transcription Factor 1 Is Required for Maintenance of Ciliary Beating in Mice J. Biol. Chem., December 21, 2007; 282(51): 37285 - 37292. [Abstract] [Full Text] [PDF]

				P. Yang, D. R. Diener, C. Yang, T. Kohno, G. J. Pazour, J. M. Dienes, N. S. Agrin, S. M. King, W. S. Sale, R. Kamiya, et al. Radial spoke proteins of Chlamydomonas flagella J. Cell Sci., March 15, 2006; 119(6): 1165 - 1174. [Abstract] [Full Text] [PDF]

				H. R. Dawe, H. Farr, N. Portman, M. K. Shaw, and K. Gull The Parkin co-regulated gene product, PACRG, is an evolutionarily conserved axonemal protein that functions in outer-doublet microtubule morphogenesis J. Cell Sci., December 1, 2005; 118(23): 5421 - 5430. [Abstract] [Full Text] [PDF]

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				J. Shapiro, J. Ingram, and K. A. Johnson Characterization of a Molecular Chaperone Present in the Eukaryotic Flagellum Eukaryot. Cell, September 1, 2005; 4(9): 1591 - 1594. [Abstract] [Full Text] [PDF]

				Y. Satouh, P. Padma, T. Toda, N. Satoh, H. Ide, and K. Inaba Molecular Characterization of Radial Spoke Subcomplex Containing Radial Spoke Protein 3 and Heat Shock Protein 40 in Sperm Flagella of the Ascidian Ciona intestinalis Mol. Biol. Cell, February 1, 2005; 16(2): 626 - 636. [Abstract] [Full Text] [PDF]

				C. Yang, M. M. Compton, and P. Yang Dimeric Novel HSP40 Is Incorporated into the Radial Spoke Complex during the Assembly Process in Flagella Mol. Biol. Cell, February 1, 2005; 16(2): 637 - 648. [Abstract] [Full Text] [PDF]

				L. S. Jones, B. Yazzie, and C. R. Middaugh Polyanions and the Proteome Mol. Cell. Proteomics, August 1, 2004; 3(8): 746 - 769. [Abstract] [Full Text] [PDF]

				C. Casano, F. Gianguzza, M. C. Roccheri, R. Di Giorgi, L. Maenza, and M. A. Ragusa Hsp40 Is Involved in Cilia Regeneration in Sea Urchin Embryos J. Histochem. Cytochem., December 1, 2003; 51(12): 1581 - 1587. [Abstract] [Full Text] [PDF]

				K Ersfeld and K Gull Targeting of cytoskeletal proteins to the flagellum of Trypanosoma brucei J. Cell Sci., January 1, 2001; 114(1): 141 - 148. [Abstract] [PDF]

				P. Bastin, T. H. MacRae, S. B. Francis, K. R. Matthews, and K. Gull Flagellar Morphogenesis: Protein Targeting and Assembly in the Paraflagellar Rod of Trypanosomes Mol. Cell. Biol., December 1, 1999; 19(12): 8191 - 8200. [Abstract] [Full Text] [PDF]

				A. Roobol, Z. P. Sahyoun, and M. J. Carden Selected Subunits of the Cytosolic Chaperonin Associate with Microtubules Assembled in Vitro J. Biol. Chem., January 22, 1999; 274(4): 2408 - 2415. [Abstract] [Full Text] [PDF]

				S. Miller and D. Kirk glsA, a Volvox gene required for asymmetric division and germ cell specification, encodes a chaperone-like protein Development, January 2, 1999; 126(4): 649 - 658. [Abstract] [PDF]

				M. Oka, M. Nakai, T. Endo, C. R. Lim, Y. Kimata, and K. Kohno Loss of Hsp70-Hsp40 Chaperone Activity Causes Abnormal Nuclear Distribution and Aberrant Microtubule Formation in M-phase of Saccharomyces cerevisiae J. Biol. Chem., November 6, 1998; 273(45): 29727 - 29737. [Abstract] [Full Text] [PDF]

				G. J. Pazour, C. G. Wilkerson, and G. B. Witman A Dynein Light Chain Is Essential for the Retrograde Particle Movement of Intraflagellar Transport (IFT) J. Cell Biol., May 18, 1998; 141(4): 979 - 992. [Abstract] [Full Text] [PDF]

				R. E. Stephens Synthesis and Turnover of Embryonic Sea Urchin Ciliary Proteins during Selective Inhibition of Tubulin Synthesis and Assembly Mol. Biol. Cell, November 1, 1997; 8(11): 2187 - 2198. [Abstract] [Full Text]

				G. Piperno and K. Mead Transport of a novel complex in the cytoplasmic matrix of Chlamydomonas�flagella PNAS, April 29, 1997; 94(9): 4457 - 4462. [Abstract] [Full Text] [PDF]

				P Liang and T. MacRae Molecular chaperones and the cytoskeleton J. Cell Sci., January 7, 1997; 110(13): 1431 - 1440. [Abstract] [PDF]

				N. Williams and E. Nelsen HSP70 and HSP90 homologs are associated with tubulin in hetero-oligomeric complexes, cilia and the cortex of Tetrahymena J. Cell Sci., January 7, 1997; 110(14): 1665 - 1672. [Abstract] [PDF]