Membrane association of cathepsin B can be induced by transfection of human breast epithelial cells with c-Ha-ras oncogene

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Achkar, C., Gong, Q., Frankfater, A. and Bajkowski, A. S (1990). Differences in targeting and secretion of cathepsins B and L by BALB/3T3 fibroblasts and Moloney murine sarcoma virus transformed BALB/3T3 fibroblasts. J. Biol. Chem 265, 13650-13654.[Abstract/Free Full Text]

Baron, R (1989). Molecular mechanisms of bone resorption by the osteoclast. Anat. Rec 224, 317-324.[Medline]

Basolo, F., Elliot, J., Tait, L., Chen, Q. C., Maloney, T. M., Russo, I. H., Pauley, R., Momiki, S., Caamano, J., Klein-Szanto, A. J. P., Koszalka, M. and Russo, J (1991). Transformation of human breast epithelial cells by c-Ha-ras oncogene. Mol. Carcinogen 4, 25-35.[Medline]

Casciola-Rosen, L., Renfrew, C. A. and Hubbard, A. L (1992). Lumenal labeling of rat hepatocyte endocytic compartments. Distribution of several acid hydrolases and membrane receptors. J. Biol. Chem 267, 11856-11864.[Abstract/Free Full Text]

Chambers, A. F., Colella, R., Denhardt, D. and Wilson S. M (1992). Increased expression of cathepsin-L and cathepsin-B and decreased activity of their inhibitors in metastatic, ras- transformed NIH-3T3 cells. Mol. Carcinogen 5, 238-245.[Medline]

Downs, T. R. and Wilfinger, W. W (1983). Fluorometric quantitation of DNA in cells and tissues. Anal. Biochem 131, 538-547.[Medline]

Erickson, A. H (1989). Biosynthesis of lysosomal endopeptidases. J. Cell. Biochem 40, 31-41.[Medline]

Gong, Q., Chan, S. J., Bajkowski, A. S., Steiner, D. F. and Frankfater, A (1993). Characterization of the cathepsin B gene and multiple mRNAs in human tissues: evidence for alternative splicing of cathepsin B pre-mRNA. DNA Cell Biol 12, 299-309.[Medline]

Guagliardi, L. E., Koppelman, B., Blum, J. S., Marks, M. S., Cresswell, P. and Brodsky, F. M (1990). Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment. Nature 343, 133-139.[Medline]

Hanewinkel, H., Glossl, J. and Kresse, H (1987). Biosynthesis of cathepsin B in cultured normal and I-cell fibroblasts. J. Biol. Chem 262, 12351-12355.[Abstract/Free Full Text]

Heuser, J (1989). Changes in lysosomal shape and distribution correlated with changes in cytoplasmic pH. J. Cell Biol 108, 855-864.[Abstract/Free Full Text]

Kane, S. E. and Gottesman, M. M (1990). The role of cathepsin L in malignant transformation. Semin. Cancer Biol 1, 127-136.[Medline]

Lehrach, H., Diamond, D., Wozney, J. M. and Boedtker, H (1977). RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination. Biochemistry 16, 4743-4751.[Medline]

Lombardi, D., Soldati, T., Riederer, M. A., Goda, Y., Zerial, M. and Pfeffer, S. R (1993). Rab9 functions in transport between late endosomes and the trans Golgi network. EMBO J 12, 677-682.[Medline]

Maciewicz, R. A., Wardale, R. J., Etherington, D. J. and Paraskeva, C (1989). Immunodetection of cathepsins B and L present in and secreted from human pre-malignant and malignant colorectal tumour cell lines. Int. J. Cancer 43, 478-486.[Medline]

Miller, F. R., Soule, H. D., Tait, L., Pauley, R. J., Wolman, S. R., Dawson, P. J. and Heppner, G. H (1993). Xenograft model of human proliferative breast disease. J. Nat. Cancer Inst 85, 1725-1732.[Abstract/Free Full Text]

Moin, K., Rozhin, J., McKernan, T. B., Sanders, V. J., Fong, D., Honn, K. V. and Sloane, B. F (1989). Enhanced levels of cathepsin B mRNA in murine tumors. FEBS Lett 244, 61-64.[Medline]

Moin, K., Day, N. A., Sameni, M., Hasnain, S., Hirama, T. and Sloane, B. F (1992). Human tumour cathepsin B: comparison with normal human liver cathepsin B. Biochem. J 285, 427-434.

Mort, J. S., Leduc, M. and Recklies, A (1981). A latent thiol proteinase from ascitic fluid of patients with neoplasia. Biochim. Biophys. Acta 662, 173-180.[Medline]

Murnane, M. J., Sheahan, K., Ozdemirli, M. and Shuja, S (1991). Stage-specific increases in cathepsin B messenger RNA content in human colorectal carcinoma. Cancer Res 51, 1137-1142.[Abstract/Free Full Text]

Ochieng, J., Basolo, F., Albini, A., Melchiori, A., Watanabe, H., Elliott, J., Raz, A., Parodi, S. and Russo, J (1991). Increased invasive, chemotactic and locomotive abilities of c-Ha-ras-transformed human breast epithelial cells. Invasion Metast 11, 38-47.[Medline]

Parton, R. G., Dotti, C. G., Bacallao, R., Kurtz, I., Simons, K and Prydz, K (1991). pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells. J. Cell Biol 113, 261-274.[Abstract/Free Full Text]

Pelham, H. R. B (1991). Multiple targets for brefeldin A. Cell 67, 449-451.[Medline]

Poole, A. R., Tiltman, K. J., Recklies, A. D. and Stoker, T. A. M (1980). Differences in the secretion of the proteinase cathepsin B at the edges of human breast carcinomas and fibroadenomas. Nature 273, 545-547.

Qian, F., Bajkowski, A. S., Steiner, D. F., Chan, S. J. and Frankfater, A (1989). Expression of five cathepsins in murine melanomas of varying metastatic potential and normal tissues. Cancer Res 49, 4870-4875.[Abstract/Free Full Text]

Recklies, A. D., Tiltman, K. J., Stoker, T. A. M. and Poole, A. R (1980). Secretion of proteinases from malignant and nonmalignant human breast tissue. Cancer Res 40, 550-556.[Abstract/Free Full Text]

Recklies, A. D., Poole, A. R. and Mort, J. S (1982). A cysteine proteinase secreted from human breast tumors is immunologically related to cathepsin B. Biochem. J 207, 633-636.[Medline]

Reilly, J. J., Mason, R. W., Chen, P., Joseph, L. J., Sukhatme, V. P., Yee, R. and Chapman, H. A (1989). Synthesis and processing of cathepsin L, an elastase, by human alveolar macrophages. Biochem. J 257, 493-498.[Medline]

Ridley, A. J. and Hall, A (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.[Medline]

Ridley, A. J., Paterson, H. F., Johnston, C. L., Diekmann, D. and Hall, A (1992). The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70, 401-410.[Medline]

Rijnboutt, S., Stoorvogel, W., Geuze, H. J. and Strous, G. J (1992). Identification of subcellular compartments involved in biosynthetic processing of cathepsin D. J. Biol. Chem 267, 15665-15672.[Abstract/Free Full Text]

Rochefort, H (1990). Biological and clinical significance of cathepsin D in breast cancer. Semin. Cancer Biol 1, 153-160.[Medline]

Rochefort, H., Capony, F. and Garcia, M (1990). Cathepsin D: a protease involved in breast cancer metastasis. Cancer Metast. Rev 9, 321-331.[Medline]

Rodman, J. S., Levy, M. A., Diment, S. and Stahl, P. D (1990). Immunolocalization of endosomal cathepsin D in rabbit alveolar macrophages. J. Leuk. Biol 48, 116-122.[Abstract]

Roederer, M., Bowser, R. and Murphy, R. F (1987). Kinetics and temperature dependence of exposure of endocytosed material to proteolyticenzymes and low pH: evidence for a maturation model for the formation of lysosomes. J. Cell. Physiol 131, 200-209.[Medline]

Rowan, A. D., Mason, P., Mach, L. and Mort, J. S (1992). Rat procathepsin B. Proteolytic processing to the mature form in vitro. J. Biol. Chem 267, 15993-15999.[Abstract/Free Full Text]

Rozhin, J., Robinson, D., Stevens, M. A., Lah, T. T., Honn, K. V., Ryan, R. E. and Sloane, B. F (1987). Properties of a plasma membrane-associated cathepsin B-like cysteine proteinase in metastatic melanoma variants. Cancer Res 47, 6620-6628.

Silver, I. A., Murrills, R. J. and Etherington, D. J (1988). Microelectrode studies on the acid microenvironment beneath adherent macrophages and osteoclasts. Exp. Cell Res 175, 266-276.[Medline]

Skudlarek, M. D. and Swank, R. T (1981). Turnover of two lysosomal enzymes in macrophages. J. Biol. Chem 256, 10137-10144.[Free Full Text]

Sloane, B. F (1990). Cathepsin B and cystatins: evidence for a role in cancer progression. Semin. Cancer Biol 1, 137-152.[Medline]

Sloane, B. F., Moin, K., Krepela, E. and Rozhin, J (1990). Cathepsin B and its endogenous inhibitors: role in tumor malignancy. Cancer Metas. Rev 9, 333-352.[Medline]

Sloane, B. F., Rozhin, J., Krepela, E., Ziegler, G. and Sameni, M (1991). The malignant phenotype and cysteine proteinases. Biomed. Biochim. Acta 50, 549-554.[Medline]

Soule, H., Maloney, T. M., Wolman, S. R., Peterson, Jr. W. D., Brenz, R., McGrath, C. M., Russo, J., Pauley, R. J., Jones, R. F. and Brooks, S. C (1990). Isolation and characterization of a spontaneously immortalized human breast epithelial cell line MCF-10. Cancer Res 50, 6075-6086.[Abstract/Free Full Text]

Tait, L., Soule, H. and Russo, J (1990). Ultrastructural and immunocytochemical characterization of an immortalized human breast epithelial cell line MCF-10. Cancer Res 50, 6087-6094.[Abstract/Free Full Text]

Tapper, H. and Sundler, R (1990). Role of lysosomal and cytosolic pH in the regulation of macrophage lysosomal enzyme secretion. Biochem. J 272, 407-414.[Medline]

Tardieux, I., Webster, P., Ravesloot, J., Boron, W., Lunn, J. A., Heuser, J. E. and Andrews, N. W (1992). Lysosome recruitment and fusion are early events required for trypanosome invasion of mammalian cells. Cell 71, 1117-1130.[Medline]

Tomoda, H., Kishimoto, Y. and Lee, Y. C (1989). Temperature effect on endocytosis and exocytosis by rabbit alveolar macrophages. J. Biol. Chem 264, 15445-15450.[Abstract/Free Full Text]

Willingham, M. C (1990). Immunocytochemical methods: useful and informative tools for screening hybridomas and evaluating antigen expression. Focus 12, 62-67.

Zhang, J.-Y. and Schultz, R. M (1992). Fibroblasts transformed by different ras oncogenes show dissimilar patterns of protease gene expression and regulation. Cancer Res 52, 6682-6689.[Abstract/Free Full Text]

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				O. Goldshmidt, E. Zcharia, R. Abramovitch, S. Metzger, H. Aingorn, Y. Friedmann, V. Schirrmacher, E. Mitrani, and I. Vlodavsky Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis PNAS, July 23, 2002; 99(15): 10031 - 10036. [Abstract] [Full Text] [PDF]

				A. M. Szpaderska and A. Frankfater An Intracellular Form of Cathepsin B Contributes to Invasiveness in Cancer Cancer Res., April 1, 2001; 61(8): 3493 - 3500. [Abstract] [Full Text]

				K. Lorenzo, P. Ton, J. L. Clark, S. Coulibaly, and L. Mach Invasive Properties of Murine Squamous Carcinoma Cells: Secretion of Matrix-degrading Cathepsins Is Attributable to a Deficiency in the Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Cancer Res., August 1, 2000; 60(15): 4070 - 4076. [Abstract] [Full Text]

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				C. C. Calkins, M. Sameni, J. Koblinski, B. F. Sloane, and K. Moin Differential Localization of Cysteine Protease Inhibitors and a Target Cysteine Protease, Cathepsin B, by Immuno-Confocal Microscopy J. Histochem. Cytochem., June 1, 1998; 46(6): 745 - 752. [Abstract] [Full Text]

				S. Mehtani, Q. Gong, J. Panella, S. Subbiah, D. M. Peffley, and A. Frankfater In Vivo Expression of an Alternatively Spliced Human Tumor Message That Encodes a Truncated Form of Cathepsin B. SUBCELLULAR DISTRIBUTION OF THE TRUNCATED ENZYME IN COS CELLS J. Biol. Chem., May 22, 1998; 273(21): 13236 - 13244. [Abstract] [Full Text] [PDF]

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				A.-R. Strohmaier, T. Porwol, H. Acker, and E. Spiess Tomography of Cells by Confocal Laser Scanning Microscopy and Computer-assisted Three-dimensional Image Reconstruction: Localization of Cathepsin B in Tumor Cells Penetrating Collagen Gels In Vitro J. Histochem. Cytochem., July 1, 1997; 45(7): 975 - 984. [Abstract] [Full Text]