A Rab4-like GTPase in Dictyostelium discoideum colocalizes with V-H(+)-ATPases in reticular membranes of the contractile vacuole complex and in lysosomes

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Aubry, L., Klein, G., Martiel, J. and Satre, M (1993). Kinetics of endosomal pH evolution in Dictyostelium discoideum amoebae. J. Cell Sci 105, 861-866.[Abstract]

Bourne, H. R., Sanders, D. A. and McCormick, F (1990). The GTPase superfamily: a conserved switch for diverse cell functions. Nature 348, 125-132.[Medline]

Bourne, H. R., Sanders, D. A. and McCormick, F (1991). The GTPase superfamily: conserved structure and molecular mechanism. Nature 349, 117-127.[Medline]

Bucci, C., Parton, R., Mather, I., Stunnenberg, H., Simons, K., Hoflack, B. and Zerial, M (1992). The GTPase Rab 5 functions as a regulatory factor in the early endocytic pathway. Cell 70, 715-728.[Medline]

Bush, J. and Cardelli, J (1989). Processing, transport, and secretion of acid phosphatase in Dictyostelium discoideum. J. Biol. Chem 264, 7630-7636.[Abstract/Free Full Text]

Bush, J. and Cardelli, J (1993). Molecular cloning and DNA sequence of a Dictyostelium cDNA encoding a Ran/TC4 related GTP binding protein belonging to the ras superfamily. Nucl. Acids Res 21, 1675-.[Free Full Text]

Bush, J., Franek, K. and Cardelli, J (1993). Cloning and characterization of seven novel Dictyostelium discoideum rac-related genes belonging to the rho family of GTPases. Gene 136, 61-68.[Medline]

Bush, J., Franek, K., Daniel, J., Speigelman, G., Weeks, G. and Cardelli, J. A (1993). Cloning and characterization of five novel Dictyostelium discoideum rab-related genes. Gene 136, 55-60.[Medline]

Cardelli, J. A., Golumbeski, G. S. and Dimond, R. L (1986). Lysosomal enzymes in Dictyostelium discoideum are transported at distinctly different rates. J. Cell Biol 102, 1264-1270.[Abstract/Free Full Text]

Cardelli, J. A., Richardson, J. M. and Miears, D (1989). Role of acidic intracellular compartments in the biosynthesis of Dictyostelium lysosomal enzymes: the weak bases ammonium chloride and chloroquine differentially affect proteolytic processing and sorting. J. Biol. Chem 264, 3454-3463.[Abstract/Free Full Text]

Cardelli, J. A., Bush, J. M and Freeze, H. H (1990). Sulfate on N-linked oligosaccharides affect secretion but is not essential for the transport, proteolytic processing, and sorting of lysosomal enzymes in Dictyostelium discoideum. J. Biol. Chem 265, 8847-8853.[Abstract/Free Full Text]

Cardelli, J. A., Schatzle, J., Bush, J. M., Richardson, J. M., Ebert, D. L. and Freeze, H. H (1990). Biochemical and genetic analysis of the biosynthesis, sorting and secretion of Dictyostelium lysosomal enzymes. Dev. Genet 11, 454-462.[Medline]

Chavrier, P., Parton, R. G., Hauri, H. P., Simons, K. and Zerial, M (1990). Localization of low molecular weight GTP-binding proteins to exocytic and endocytic compartments. Cell 62, 317-329.[Medline]

Ebert, D. L., Freeze, H. H., Richardson, J. M., Dimond, R. L. and Cardelli, J. A (1989). A Dictyostelium discodieum mutant that missorts andoversecretes lysosomal enzyme precursors is defective in endocytosis. J. Cell Biol 109, 1445-1456.[Abstract/Free Full Text]

Daniels, J., Bush, J., Cardelli, J., Spiegelman, G. and Weeks, G (1993). Characterization of two novel ras genes that are maximally expressed during aggregation of Dictyostelium discoideum. Oncogene 9, 501-509.

Fok, A., Clarke, M., Ma, L. and Allen, R (1994). Vacuolar H+-ATPase of Dictyostelium discoideum : a monoclonal antibody study. J. Cell Sci 106, 1103-1113.[Abstract]

Free, S. and Loomis, W (1974). Isolations of mutations in Dictyostelium discoideum affecting-mannosidase. Biochimie 56, 1525-1528.[Medline]

Freeze, H. H (1986). Modifications of lysosomal enzymes in Dictyostelium discoideum. Mol. Cell. Biochem 72, 47-65.[Medline]

Goud, B. and McCaffrey, M (1991). Small GTP-binding proteins and their role in transport. Curr. Opin. Cell Biol 3, 626-633.[Medline]

Heuser, J.. Zhu, Q. and Clarke, M (1993). Proton pumps populate the contractile vacuoles of Dictyostelium discoideum. J. Cell Biol 121, 1311-1327.[Abstract/Free Full Text]

Lombardi, D., Soldati, T., Riederer, N., Goda, Y., Zerial, M. and Pfeffer, S (1993). Rab9 functions in transport between late endosomes and the trans Golgi network. EMBO J 12, 677-682.[Medline]

Mierendorf, R. C., Cardelli, J. A. and Dimond, R. L (1985). Pathways involved in targeting and secretion of a lysosomal enzyme in Dictyostelium discoideum. J. Cell Biol 100, 1777-1787.[Abstract/Free Full Text]

Nolta, K. V., Padh, H. and Steck, T (1991). Acidosomes from Dictyostelium: initial biochemical characterization. J. Biol. Chem 266, 18318-18323.[Abstract/Free Full Text]

Nolta, K. V., Padh, H. and Steck, T. L (1993). An immunochemical analysis of the vacuolar proton pump in Dictyostelium discoideum. J. Cell Sci 105, 849-859.[Abstract]

Nolta, K. V. and Steck, T. L (1994). Isolation and initial characterization of the bipartite contractile vacuole complex from Dictyostelium discoideum. J. Biol. Chem 269, 2225-2233.[Abstract/Free Full Text]

O'Halloran, T. J. and Anderson, R. G (1992). Clathrin heavy chain is required for pinocytosis, the presence of large vacuoles, and development in Dictyostelium. J. Cell Biol 118, 1371-1377.[Abstract/Free Full Text]

Padh, H., Lavasa, M. and Steck, T. L (1991). Endosomes are acidified by association with discrete proton-pumping vacuoles in Dictyostelium. J. Biol. Chem 266, 5514-5520.[Abstract/Free Full Text]

Padh, H., Lavasa, M. and Steck, T. L (1991). Reconstitution of the association of endocytic vacuoles and acidosomes from Dictyostelium. J. Biol. Chem 266, 12123-12126.[Abstract/Free Full Text]

Padh, H., Ha, J., Lavasa, M. and Steck, T. L (1993). A post-lysosomal compartment in Dictyostelium discoideum. J. Biol. Chem 268, 6742-6747.[Abstract/Free Full Text]

Pryer, N. K., Wuestehube, L. J. and Schekman, R (1992). Vesicle mediated protein sorting. Annu. Rev. Biochem 61, 471-516.[Medline]

Reymond, C. D., Gomer, R. H., Mehdy, M. C. and Firtel, R. A (1984). Developmental regulation of a Dictyostelium gene encoding a protein homologous to mammalian Ras protein. Cell 39, 141-148.[Medline]

Richardson, J. R., Woychik, N. A., Ebert, D. L., Dimond, R. L. and Cardelli, J. A (1988). Inhibition of early but not late proteolytic processing events induces the missorting and oversecretion of precursor forms of lysosomal enzymes in Dictysotelium discoideum. J. Cell Biol 107, 2097-2107.[Abstract/Free Full Text]

Robbins, S. M., Williams, J. G., Jermyn, K. A., Spiegelman, G. B. and Weeks, G (1989). Growing and developing Dictyostelium cells express different ras genes. Proc. Nat. Acad. Sci. USA 86, 938-942.[Abstract/Free Full Text]

Robbins, S. M., Suttorp, V. V, Weeks, G. and Spiegelman, G. B (1990). A ras-related gene from the lower eukaryote Dictyostelium that is highly conserved relative to the human rap genes. Nucl. Acids Res 18, 5265-5269.[Abstract/Free Full Text]

Rodriguez-Paris, J. M., Nolta, K. V. and Steck, T. L (1993). Characterization of lysosomes isolated from Dictyostelium discoideum by magnetic fractionation. J. Biol. Chem 268, 9110-9116.[Abstract/Free Full Text]

Rothman, J. and Orci, L (1992). Molecular dissection of the secretory pathway. Nature 355, 409-415.[Medline]

Saxe, S. and Kimmel, A. R (1990). SAS1 and SAS2, GTP-binding protein genes in Dictyostelium discoideum with sequence similarities to essential genes in Saccharomyces cerevisiae. Mol. Cell. Biol 10, 2367-2378.[Abstract/Free Full Text]

Schatzle, J., Rathi, A., Clarke, M. and Cardelli, J (1991). Developmental regulation of the-mannosidase gene in Dictyostelium: control is at the level of transcription and is affected by cell density. Mol. Cell. Biol 11, 3339-3347.[Abstract/Free Full Text]

Schatzle, J. Bush, J. and Cardelli, J (1992). Molecular cloning and characterization of the structural gene coding for the developmentally regulated lysosomal enzyme-mannosidase in Dictyostelium discoideum. J. Biol. Chem 252, 4000-4007.

Tisdale, E. J., Bourne, J. R., Khosravi-far, R., Der, C. J. and Balch, W. E (1992). GTP binding mutants of Rab1 and Rab2 are potent inhibitors of vesicular transport from the ER to the Golgi complex. J. Cell Biol 119, 749-761.[Abstract/Free Full Text]

Valencia, A., Chardin, P., Wittinghofer, A. and Sander, C (1991). The Ras protein family: evolutionary tree and role of conserved amino acids. Biochemistry 30, 4637-4648.[Medline]

van der Sluijs, P., Hull, M., Zahraoui, A., Tavitian, A., Goud, B. and Mellman, I (1991). The small GTP binding protein Rab4 is associated with early endosomes. Proc. Nat. Acad. Sci. USA 88, 6313-6317.[Abstract/Free Full Text]

van der Sluijs, P., Hull, M., Webster, P., Male, P., Goud, B. and Mellman, I (1992). The small GTP-binding protein Rab4 controls an early sorting event on the endocytic pathway. Cell 70, 729-740.[Medline]

Wichmann, H., Hengst, L and Gallwitz, D (1992). Endocytosis in yeast: evidence for the involvement of a small GTP binding protein (Ypt7p). Cell 71, 1131-1142.[Medline]

Wood, L. and Kaplan, A (1985). Transit of-mannosidase during its maturation in Dictyostelium discoideum. J. Cell Biol 101, 2063-2069.[Abstract/Free Full Text]

Zahraoui, A., Touchot, N., Chardin, P. and Tavitian, A (1989). The human rab genes encode a family of GTP-binding proteins related to yeast Ypt1 and Sec4 products involved in secretion. J. Biol. Chem 264, 12394-12401.[Abstract/Free Full Text]

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				L. Temesvari, J. Rodriguez-Paris, J. Bush, L Zhang, and J. Cardelli Involvement of the vacuolar proton-translocating ATPase in multiple steps of the endo-lysosomal system and in the contractile vacuole system of Dictyostelium discoideum J. Cell Sci., January 6, 1996; 109(6): 1479 - 1495. [Abstract] [PDF]

				T Liu and M Clarke The vacuolar proton pump of Dictyostelium discoideum: molecular cloning and analysis of the 100 kDa subunit J. Cell Sci., January 5, 1996; 109(5): 1041 - 1051. [Abstract] [PDF]

				M Ishida, A. Fok, M. Aihara, and R. Allen Hyperosmotic stress leads to reversible dissociation of the proton pump-bearing tubules from the contractile vacuole complex in Paramecium J. Cell Sci., January 1, 1996; 109(1): 229 - 237. [Abstract] [PDF]