Heterogeneity of thymic stromal cells and thymocyte differentiation: a cell culture approach

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Screpanti, I.
	Articles by Gulino, A.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Screpanti, I.
	Articles by Gulino, A.

Auerbach, R (1960). Morphogenetic interactions in the development of the mouse thymus gland. Dev. Biol 2, 271-279.

Benoist, C. and Mathis, D (1989). Positive selection of the T-cell repertoire: where and when does it occur?. Cell 58, 1027-1033.[Medline]

Bluestone, J. A., Pardoll, D., Sharrow, S. O. and Fowlkes, B. J (1987). Characterization of murine thymocytes with CD3-associated T-cell receptor structures. Nature 326, 82-85.[Medline]

Bockman, D. E. and Kirby, M. L (1984). Dependence of thymus development on derivatives of the neural crest. Science 223, 498-500.[Abstract/Free Full Text]

Born, W., McDuffie, M., Roehm, N., Kshnir, E., White, J., Thorpe D., Stefano, J., Kappler, J. and Marrack, P (1987). Expression and role of the T cell receptor in early thymocyte differentiation in vitro. J. Immunol 138, 999-1008.[Abstract/Free Full Text]

Boyd, R. L. and Hugo, P (1991). Towards an integrated view of thymopoiesis. Immunol. Today 12, 71-79.[Medline]

Brekelmans, P. and Van Ewjik, W (1990). Phenotypic characterization of murine thymic microenvironments. Sem. Immunol 2, 13-24.[Medline]

Calvo, C. F., Chavanel, G. and Senik, A (1992). Substance P enhances IL-2 expression in activated human T cells. J. Immunol 148, 3498-3504.[Abstract]

Carlow, D. A., Van Oers, N. C. S., Teh, S.-J and Teh, H.-S (1992). Deletion of antigen-specific immature thymocytes by dendritic cells requires LFA-1/ICAM interactions. J. Immunol 148, 1595-1603.[Abstract]

Ceredig, R (1988). Differentiation potential of 14-day fetal mouse thymocytes in organ culture. Analysis of CD4/CD8-defined single-positive and double-negative cells. J. Immunol 141, 355-362.[Abstract]

Ceredig, L., Dialynas, D. P., Fitch, F. W. and MacDonald, H. R (1983). Precursors of T cell growth factor producing cells in the thymus: ontogeny, frequency and quantitative recovery in a subpopulation of phenotypically mature thymocytes defined by monoclonal antibody GK-1. 5. J. Exp. Med 158, 1654-1671.[Abstract/Free Full Text]

Cosgrove, D., Gray, D., Dierich, A., Kaufman, J., Lemeur, M., Benoist, C. and Mathis, D (1991). Mice lacking MHC class II molecules. Cell 66, 1051-1066.[Medline]

Denning, S. M., Tuck, D. T., Vollger, L. W., Springer, T. A., Singer, K. H. and Haynes, B. F (1987). Monoclonal antibodies to CD2 and lymphocyte associated antigen 3 inhibit human thymic epithelial cell dependent mature thymocyte activation. J. Immunol 139, 2573-2577.[Abstract]

Duyvestyn, A. M., Kohler, Y. G. and Hoefsmit, E. C. M (1982). Interdigitating cells and macrophages in the acute involuting rat thymus. An electronmicroscopic study on phagocytic activity and population development. Cell Tiss. Res 224, 291-301.[Medline]

Ericson, A., Geenen, V., Robert, F., Legross, J. J., Urindts-Gevaert, Y., Franchimont, P., Brem, S. and Persson, H (1990). Expression of pre-protachykinin-A and neuropeptide-Y messenger RNA in the thymus. Mol. Endocrinol 4, 1211-1218.[Medline]

Ferrick, D. A., Ohashi, P. S., Wallace, V., Schilham, M. and Mak, T. W (1989). Thymic ontogeny and selection ofand cells. Immunol. Today 10, 403-407.[Medline]

Fine, J. S. and Kruisbeek, A. M (1991). The role of LFA-1/ICAM-1 interactions during murine T lymphocyte development. J. Immunol 147, 2854-2859.

Fuller, P. J. and Verity, K (1989). Somatostatin gene expression in the thymus gland. J. Immunol 143, 1015-1017.[Abstract]

Geenen, V., Legross, J. J., Franchimont, P., Baudrihaye, M., Defresne, M. P. and Boniver, J (1986). The neuroendocrine thymus: coexistence of oxytocin and neurophysin in the human thymus. Science 232, 508-511.[Abstract/Free Full Text]

Geenen, V., Robert, F., Fatemi, M., Martens, H., Defresne, M. P., Boniver, J., Legross, J. J. and Franchimont, P (1989). Neuroendocrine-immune interactions in T-cell ontogeny. Thymus 13, 131-140.[Medline]

Gutierrez, J. C. and Palacios, R (1991). Heterogeneity of thymic epithelial cells in promoting T-lymphocyte differentiation in vivo. Proc. Nat. Acad. Sci. USA 88, 642-646.[Abstract/Free Full Text]

Hall, A. K. and Rao, M. S (1992). Cytokines and neurokines: related ligands and related receptors. Trends Neurosci 15, 35-37.[Medline]

Hattori, M., Sudo, T., Izawa, H., Kano, S. and Minato, N (1989). Developmental regulation of the extrathymic differentiation potential of the progenitor cells for T-cell lineage. Int. Immunol 1, 151-159.[Abstract/Free Full Text]

Hawran, W. L. and Allison, J. P (1988). Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors. Nature 335, 443-445.[Medline]

Ip, N. Y., Nye, S. H., Boulton, T. G., Davis, S., Taga T., Li, Y., Birren, S. D., Yasukawa, K., Kishimoto, T., Anderson, D. J., Stahl, N. and Yancopoulos, G. D (1992). CNTF and LIF act on neuronal cells via shared signalling pathways that involve the IL-6 signal transducing receptor component gp130. Cell 69, 1121-1132.[Medline]

Iwabuchi, K., Nakayama, K.-I., McCoy, R. L. Wang, F., Nishimura, T., Habu, S., Murphy, K. M. and Loh, D. Y (1992). Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes. Proc. Nat. Acad. Sci. USA 89, 9000-9004.[Abstract/Free Full Text]

Jenkinson, E. J., Franchi, L. L., Jenkinson, R. and Owen, J. J. T (1982). Effect of deoxyguanosine on lymphopoiesis in the developing thymus rudiment in vitro: application in the production of chimeric thymic rudiments. Eur. J. Immunol 12, 583-588.[Medline]

Jenkinson, E. J., Van Ewijk, W. and Owen, J. J. T (1981). Major histocompatibility complex antigen expression on the epithelium of the developing thymus in normal and nude mice. J. Exp. Med 153, 280-292.[Abstract/Free Full Text]

Jordan, R. K., Robinson, J. H. and Waggott, E (1979). A qualitative and quantitative study of macrophages in the developping mouse thymus. J. Anat 129, 871-880.

Kampinga, J., Berger, S., Boyd, R., Brekelmans, P., Colic, M., Van Ewijk, W., Kendall, M., Ladyman, H., Nienwenhuis, P., Ritter, M., Schurman, H. J. and Tournefier, A (1989). Thymic epithelial antibodies: immunohistological analysis and introduction of CTES nomenclature. Thymus 13, 165-173.[Medline]

Kosaka, H., Matsubara, H., Sogoh, S., Ogata, M., Hamaoka, T. and Fujiwara, H (1990). An in vitro model for Cyclosporin A-induced interference of intrathymic clonal elimination. J. Exp. Med 172, 395-398.[Abstract/Free Full Text]

Kosaka, H., Ogata, M., Hikita, I., Maruo, S., Sugihara, S., Matsubara, H., Takai, Y., Hamaoka, T. and Fujiwara, H (1989). Model for clonal elimination in the thymus. Proc. Nat. Acad. Sci. USA 86, 3773-3777.[Abstract/Free Full Text]

Kraal, G., Avis, L., Wijffels, J., Hoeben K. and ter Hart, H (1990). Different epitopes on the dendritic cell-associated NLDC-45 molecule during ontogeny. Immunobiology 181, 388-397.[Medline]

Kuhn, R., Rajewsky, K. and Muller W (1991). Generation and analysis of interleukin-4 deficient mice. Science 254, 707-710.[Abstract/Free Full Text]

Kyewski, B. A., Fathman, C. G. and Kaplan, H. S (1984). Intrathymic presentation of circulating non-major histocompatibility complex antigens. Nature 308, 196-199.[Medline]

Kyewski, B. A., Rouse, R. V. and Kaplan, H. S (1982). Thymocyte rosettes: multicellular complexes of lymphocytes and bone marrow-derived stromal cells in the mouse thymus. Proc. Nat. Acad. Sci. USA 79, 5646-5650.[Abstract/Free Full Text]

Le Lievre C. S. and Le Douarin, N. M (1975). Mesenchymal derivatives of the neural crest: analysis of chimeric quail and chick embryos. J. Embryol. Exp. Morphol 31, 453-477.

Le, P. T., Lazorick, S., Whichard, L. P., Haynes, B. F. and Singer, K. H (1991). Regulation of cytokine production in the human thymus: epidermal growth factor and transforming growth factorregulate mRNA levels of interleukin 1 (IL-1), IL-1 and IL-6 in human thymic epithelial cells at a post-transcriptional level. J. Exp. Med 174, 1147-1157.[Abstract/Free Full Text]

Le, P. T., Lazorick, Z. S., Whichard, L. P., Yang, Y. C., Clark, S. C.,606Haynes, B. F. and Singer, K. H (1990). Human thymic epithelial cells produce IL-6, granulocyte-monocyte-CSF and leukemia inibitory factor. J. Immunol 145, 3310-3315.[Abstract]

Le, P. T., Wollger, L. W., Haynes, B. F. and Singer, K. H (1990). Ligand binding to the LFA-3 cell adhesion molecule induces IL-1 production by human thymic epithelial cells. J. Immunol 144, 4541-4547.[Abstract]

Lobach, D. F. and Haynes, B. F (1987). Ontogeny of the human thymus during fetal development. J. Clin. Immunol 7, 81-97.[Medline]

Matsumoto, K., Yoshikai, Y., Moroi, Y., Asano, T., Ando, T. and Nomoto, K (1991). Two differential pathways from double-negative to double-positive thymocytes. Immunol 72, 20-26.[Medline]

Nakamura, H. and Ayer-Le Lievre, C (1986). Neural crest and thymic myoid cells. Curr. Top. Dev. Biol 20, 111-115.[Medline]

Nishimura, T., Takeuchi, Y. n Ichimura, Y., Gao; X., Akatsuka, A. Tamaoki, N., Yagita, H., Okumura, K. and Habu, S (1990). Thymic stromal cell clone with nursing activity supports the growth and differentiation of murine CD4+8+ thymocytes in vitro. J. Immunol 145, 4012-4017.[Abstract]

Owen, J. J. T. and Ritter, M (1969). Tissue interaction in the development of thymus lymphocytes. J. Exp. Med 129, 431-434.[Abstract]

Palacios, R., Studer, S., Samaridis, J. and Pelkonen, J (1989). Thymic epithelial cells induce in vitro differentiation of pro-T lymphocyte clones into TCR, /T3+ and TCR/T3 +cells. EMBO J 8, 4053-4063.[Medline]

Papiernik, M. and El Rouby, S (1988). Control of helper T-cell proliferation by recognition of Ia and Mac-1 antigens on phagocytic cells of the thymic reticulum. Cell. Immunol 113, 95-106.[Medline]

Pardoll, D. and Carrera, A (1992). Thymic selection. Curr. Opin. Immunol 4, 162-165.[Medline]

Penit, C (1986). In vivo thymocyte maturation. BUdR labeling of cycling thymocytes and phenotype analysis of their progeny support the single lineage model. J. Immunol 137, 2115-2124.[Abstract]

Penit, C. and Vasseur, F (1988). Sequential events in thymocyte differentiation and thymus regeneration revealed by a combination of bromodeoxyuridine DNA labeling and antimitotic drug treatment. J. Immunol 140, 3315-3323.[Abstract]

Petrie, H. T., Hugo, P., Scollay, R. and Shortman, K (1990). Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4 and CD8 acquisition in vivo and in vitro. J. Exp. Med 172, 1583-1588.[Abstract/Free Full Text]

Richman, D. P. and Arnason, B. C. W (1979). Nicotinic acetylcholine receptor: evidence for a functionally distinct receptor on human lymphocytes. Proc. Nat. Acad. Sci. USA 76, 4632-4635.[Abstract/Free Full Text]

Rocha, B., Vassalli, P. and Guy-Grand, D (1992). The extrathymic T-cell development pathway. Immunol. Today 13, 449-454.[Medline]

Roehm, N., Herron, L., Cambier, J., Di Guisto, D., Haskins, K., Kappler, J. and Marrack, P (1984). The major histocompatibility complex-restricted antigen receptor on T cells: distribution on thymus and peripheral T cells. Cell 38, 577-582.[Medline]

Rouse, R. V., Bolin, L. M., Bender, J. R. and Kyewski, B. A (1988). Monoclonal antibodies reactive with subsets of mouse and human thymic epithelial cells. J. Histochem. Cytochem 36, 1511-1517.[Abstract]

Sakata, T., Iwagami, S., Tsuruta, Y., Yamaguchi, M., Michishita, M.,Nagata, K., Takai, Y., Ogata, M., Teraoka, H. and Fujiwara, H (1992). Constitutive expression of leukemia inibitory factor (LIF) mRNA and production of LIF by a cloned murine thymic stromal cell line. Thymus 19, 89-95.[Medline]

Sano, H., Ishimura, K., Fujita, H., Hamaoka, T. and Fujiwara, H (1989). Capacities of a newly established thymic stromal cell clone to express Ia antigens and to produce interleukin-6, colony-stimulating factor, and thymic stroma-derived T-cell growth factor. J. Leukocyte Biol 45, 69-78.[Abstract]

Sawada, M., Nagamine, J., Takeda, K., Utsumi, K., Kosugi, A., Tatsumi, Y., Hamaoka, T., Miyake, K., Nakajima, K., Watanabe, T., Sakakibara, S. and Fujiwara, H (1992). Expression of VLA-4 on thymocytes. Maturation stage-associated transition and its correlation with their capacity to adhere to thymic stromal cells. J. Immunol 149, 3517-3524.[Abstract]

Schorle, H., Holtsche, T., Hunig, T., Schimpl, A. and Horak, I (1991). Development and function of T-cells in mice rendered interleukin-2 deficient by gene targeting. Nature 352, 621-626.[Medline]

Screpanti, I., Meco, D., Scarpa, S., Morrone, S., Frati, L., Gulino, A. and Modesti, A (1992). Neuromodulatory loop mediated by nerve growth factor and interleukin 6 in thymic stromal cell cultures. Proc. Nat. Acad. Sci. USA 89, 3209-3212.[Abstract/Free Full Text]

Sen-Majundar, A., Lieberman, M., Alpert, S., Weissman, I. L. and Small, M (1992). Differentiation of CD34 8thymocytes in short-term thymic stromal cell culture. J. Exp. Med 176, 543-551.[Abstract/Free Full Text]

Shortman, K (1992). Cellular aspects of early T-cell development. Curr. Opin. Immunol 4, 140-146.[Medline]

Singh, U., Millson, D. S., Smith, P. A. and Owen, J. J. T (1979). Identification of-adrenoreceptors during thymocyte ontogeny in mice. Eur. J. Immunol 9, 31-35.[Medline]

Sprent, J., Lo, D., Gao, E. K. and Ron, Y (1988). T cell selection in the thymus. Immunol. Rev 101, 173-190.[Medline]

Tatsumi, Y., Kumanogoh, A., Saitoh, M., Mizushima, Y., Kimura, K., Suzuki, S., Yagi, H., Horiuchi, A., Ogata, M., Hamaoka, T. and Fujiwara, H (1990). Differentiation of thymocytes from CD3CD4 CD8through CD3 CD4CD8 +into more mature stages induced by a thymic stromal cell clone. Proc. Nat. Acad. Sci. USA 87, 2750-2754.[Abstract/Free Full Text]

Utsumi, K., Sawada, M., Naruniya, S., Nagamine, J., Sakata, T., Iwagami, S., Kita, Y., Teraoka, H., Hirano, H., Ogata, M., Hamaoka, T. and Fujiwara, H (1991). Adhesion of immature thymocytes to thymic stromal cells through fibronectin molecules and its significance for the induction of thymocyte differentiation. Proc. Nat. Acad. Sci. USA 88, 5685-5689.[Abstract/Free Full Text]

Van de Wijngaert, F. P., Kendall, M. D., Schurman, H.-J., Rademakers, L. H. P. M. and Kater, L (1984). Heterogeneity of epithelial cells in the human thymus. An ultrastructural study. Cell Tiss. Res 237, 227-237.[Medline]

Van Vliet, E., Jenkinson, E. J., Kingston, R., Owen, J. J. T. and Van Ewijk, W (1985). Stromal cell types in the developing thymus of the normal and nude mouse embryo. Eur. J. Immunol 15, 675-681.[Medline]

Von Boehmer, H (1990). Developmental biology of T cells in T cell receptor transgenic mice. Annu. Rev. Immunol 8, 531-556.[Medline]

Von Boehmer, H (1992). Thymic selection: a matter of life and death. Immunol. Today 13, 454-458.[Medline]

Vukmanovic, S., Grandea III, A. G., Faas, S. J., Knowles, B. B. and Bevan, M. J (1992). Positive selection of T-lymphocytes induced by intrathymic injection of a thymic epithelial cell line. Nature 359, 729-732.[Medline]

This article has been cited by other articles:

M. P. Felli, M. Maroder, T. A. Mitsiadis, A. F. Campese, D. Bellavia, A. Vacca, R. S. Mann, L. Frati, U. Lendahl, A. Gulino, et al.
Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand�receptor interactions in intrathymic T cell development
Int. Immunol., July 1, 1999; 11(7): 1017 - 1025.
[Abstract] [Full Text] [PDF]

J. E. Staples, F. G. Murante, N. C. Fiore, T. A. Gasiewicz, and A. E. Silverstone
Thymic Alterations Induced by 2,3,7,8-Tetrachlorodibenzo- p-Dioxin Are Strictly Dependent on Aryl Hydrocarbon Receptor Activation in Hemopoietic Cells
J. Immunol., April 15, 1998; 160(8): 3844 - 3854.
[Abstract] [Full Text] [PDF]

This Article

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Screpanti, I.

Articles by Gulino, A.

Search for Related Content

PubMed

PubMed Citation

Articles by Screpanti, I.

Articles by Gulino, A.

				J. E. Staples, F. G. Murante, N. C. Fiore, T. A. Gasiewicz, and A. E. Silverstone Thymic Alterations Induced by 2,3,7,8-Tetrachlorodibenzo- p-Dioxin Are Strictly Dependent on Aryl Hydrocarbon Receptor Activation in Hemopoietic Cells J. Immunol., April 15, 1998; 160(8): 3844 - 3854. [Abstract] [Full Text] [PDF]