spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bayly, A. C.
Right arrow Articles by Roberts, R. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bayly, A. C.
Right arrow Articles by Roberts, R. A.
Arends, M.J., Morris, R.G. and Wyllie, A.H (1990). Apoptosis: the role of the endonuclease. Amer. J. Pathol 136, 593-608.[Abstract]

Ashby, J. and Tenant, R.W (1991). Definitive relationships among chemical structure, carcinogenicity and mutagenicity for 301 chemicals tested by the U.S. NTP. Mutat. Res 257, 229-306.[Medline]

Bars, R.G., Mitchell, A.M., Wolf, R. and Elcombe C.R (1989). Induction of cytochrome P-450 in cultured rat hepatocytes. Biochem. J 262, 151-158.[Medline]

Bieri, F., Bentley, P., Waechter F., and Staubli, W (1984). Use of primary cultures of adult rat hepatocytes to investigate mechanisms of action of nafenopin, a hepatocarcinogenic peroxisome proliferator. Carcinogenesis 5, 1033-1039.[Abstract/Free Full Text]

Bains, S.K., Gardiner, S.M., Manweiler, K., Gillett, D. and Gibson, G.G (1985). Immunocytochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachadonic acid. Biochem. Pharmacol 34, 3221-3229.[Medline]

Bursch, W., Dusterberg, B. and Schulte-Hermann, R (1986). Growth, regression and cell death in rat liver as related to tissue levels of the hepatomitogen cyproterone acetate. Arch. Toxicol 59, 221-227.[Medline]

Bursch, W., Lauer, B., Timmerman-Trosiener, I., Barthel, G., Schuppler, J. and Schulte-Hermann, R (1984). Controlled death (apoptosis) of normal and putative preneoplastc cells in rat liver following withdrawal of tumour promoters. Carcinogenesis 5, 453-458.[Abstract/Free Full Text]

Bursch, W., Paffe, S., Putz, B., Barthel, G. and Schulte-Hermann, R (1990). Determination of the length of the histological stages of apoptosis in normal liver and in altered hepatic foci of rats. Carcinogenesis 11, 847-853.[Abstract/Free Full Text]

Bursch, W., Oberhammer, F. and Schulte-Hermann, R (1992). Cell death by apoptosis and its protective role against disease. Trends Pharmacol. Sci 13, 245-251.[Medline]

Dive, C., Gregory, C.D., Phipps, D.J., Evans D.L., Milner, A.E. and Wyllie, A.H (1992). Analysis and discrimination of necrosis and apoptosis (programmed cell death) by multiparameter flow cytometry. Biochim. Biophys. Acta 1133, 275-285.[Medline]

Green, S (1991). The search for the molecular mechanisms of non-genotoxic carcinogens. Mutat. Res 248, 371-374.[Medline]

Issemann, I. and Green, S (1990). Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 347, 645-650.[Medline]

Kasai, H., Okada, Y., Nishimura, S., Rao, M.S. and Reddy, J.K (1989). Formation of 8-hydroxydeoxyguanosine in liver DNA of rats followinglong-term exposure to a peroxisome proliferator. Cancer Res 49, 2603-2605.[Abstract/Free Full Text]

Kraupp-Grasl, B., Huber, W., Taper, H. and Schulte-Hermann, R (1991). Increased susceptibility of aged rats to hepatocarcinogenesis by the peroxisome proliferator nafenopin and the possible involvement of altered liver foci occurring spontaneously. Cancer Res 51, 2-.[Abstract/Free Full Text]

Laemmli, U. K. and Favre, M (1973). Maturation of the head of bacteriophage T4. I. DNA packaging events. J. Mol. Biol 80, 575-599.[Medline]

Lake, B.G., Gray, T.J.B., Smith, A.G. and Evans, J.G (1990). Hepatic peroxisome proliferation and oxidative stress. Biochem. Soc. Trans 18, 94-97.[Medline]

Lazarow, P.B. and de Duve, C (1976). A fatty acyl-CoA oxidizing system in rat liver peroxisomes: enhancement by clofibrate, a hypolipidemic drug. Proc. Nat. Acad. Sci. USA 73, 2043-2046.[Abstract/Free Full Text]

Manson, M.M., Legg, R.F., Watson, J.V., Green, J.A. and Neal, G.E (1981). An examination of the relative resistances to aflatoxin B1 and susceptibilities to gamma-glutamyl p -phenylene diamine mustard of gamma-glutamyl transferase negative and positive cell lines. Carcinogenesis 2, 661-670.[Abstract/Free Full Text]

Marsmann, D.S., Cattley, R.C., Conway, J.G. and Popp, J.A (1988). Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats. Cancer Res 48, 6739-6744.[Abstract/Free Full Text]

McConkey, D.J., Hartzell, P., Nicotera, P. Wyllie, A.H. and Orrenius, S (1988). Stimulation of endogenous endonuclease activity in hepatocytes exposed to oxidative stress. Toxicol. Lett 42, 123-130.[Medline]

Moody, D.E., Reddy, J.K., Lake, B.G., Popp, J.A. and Reese, D.H (1991). Peroxisome proliferation and non-genotoxic carcinogenesis: commentary on a symposium. Fund. Appl. Toxicol 16, 223-248.

Muakkassah-Kelly, S.F., Bieri, F., Waechter, F., Bentley, P. and Staubli, W (1987). Long-term maintenence of hepatocytes in primary culture in the presence of DMSO: further characterisation and effect of nafenopin, a peroxisome proliferator. Exp. Cell Res 171, 37-51.[Medline]

Orton, T.C. and Parker, G.L (1982). The effect of hypolipidemic agents on the hepatic microsomal drug-metabolizing enzyme system of the rat. Drug Metab. Dispos 10, 110-115.[Abstract]

Osumi, T., Yokota, S. and Hashimoto, T (1990). Proliferation of peroxisomes and induction of peroxisomal beta-oxidation enzymes in rat hepatoma H4IIEC3 by ciprofibrate. J. Biochem. (Tokyo) 108, 4-.[Abstract/Free Full Text]

Reddy, J.K., Azarnoff, D.L. and Hignite, C.L (1980). Hypolipidemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature 283, 397-398.[Medline]

Reddy, J.K. and Lalwani, N.D (1983). Carcinogenesis by hepatic peroxisome proliferators: evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. Crit. Rev. Toxicol 12, 1-58.[Medline]

Reddy, J.K. and Rao, M.S (1989). Oxidative damage caused by persistent peroxisome proliferation: its role in hepatocarcinogenesis. Mutat. Res 214, 63-68.[Medline]

Richardson, U.I., Tashjian, A.H. Jr. and Levine, L (1969). Establishment of a clonal strain of hepatoma cells which secrete albumin. J. Cell Biol 40, 236-247.[Abstract/Free Full Text]

Schulte-Hermann, R., Bursch, W, and Parzefall, W (1991). Mitogenesis and programmed cell death as determinants of carcinogenicity of non-genotoxic compounds. Prog. Clin. Biol. Res 369, 237-44.[Medline]

Shinagawa, T., Yoshioko, K., Kakumu, S., Wakita, T., Ishikawa, T., Itoh, Y. and Takayanagi, M (1991). Apoptosis in cultured rat hepatocytes: the effects of TNFa and interferon gamma. J. Pathol 165, 247-253.[Medline]

Snodgrass, P.J. and Lin, R.C (1987). Differing effects of arginine deficiency on the urea cycle enzymes of rat liver, cultured hepatocytes and hepatoma cells. J. Nutr 117, 1827-1837.

Spydevold, O. and Bremer, J (1989). Induction of peroxisomal-oxidation in 7800C 1Morris hepatoma cells in steady state by fatty acids and fatty acid analogues. Biochim. Biophys. Acta 1003, 72-79.[Medline]

Staubli, W., Schweizer, W., Suter, J. and Weibel, E.R (1977). TheA. C. Bayly and others315Hepatocarcinogenesis in vitroproliferative response of hepatic peroxisomes of neonatal rats to treatment with SU-13 437 (nafenopin). J. Cell Biol 74, 665-689.[Abstract/Free Full Text]

Thompson, E.B., Tomkins, G.M. and Curran, J.F (1966). Induction of tyrosine a-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line. Proc. Nat. Acad. Sci. USA 56, 296-303.[Free Full Text]

Towbin, H., Staehlin, T. and Gordon, J (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Nat. Acad. Sci. USA 76, 4350-4354.[Abstract/Free Full Text]

Tugwood, J.D., Issemann, I., Anderson, R.G., Bundell, K.R., McPheat, W.L. and Green, S (1992). The mouse peroxisome proliferator activated receptor recognises a response element in the 5flanking sequence of the rat acyl-CoA oxidase gene. EMBO J 11, 433-439.[Medline]

Warren, J.F., Simmon, V.F. and Reddy, J.K (1980). Properties ofhypolipidemic peroxisome proliferators in the lymphocyte [3 H]thymidine and Salmonella mutagenesis assay. Cancer Res 40, 36-41.[Abstract/Free Full Text]

Wiebel, F.J., Park, S.S., Kiefer, F. and Gelboin, H.V (1984). Expression of cytochromes P-450 in rat hepatoma cells. Eur. J. Biochem 145, 455-462.[Medline]

Wyllie, A.H (1980). Glucocorticoid-induced apoptosis is associated with endogenous endonuclease activation. Nature 4, 555-556.

Yeldandi, A.V., Milano, M, Subbarao, V., Reddy, J.K. and Rao, M.S (1989). Evaluation of liver cell proliferation during ciprofibrate-induced hepatocarcinogenesis. Cancer Lett 47, 21-27.[Medline]




This article has been cited by other articles:


Home page
Toxicol SciHome page
H. P. Glauert, A. Eyigor, J. C. Tharappel, S. Cooper, E. Y. Lee, and B. T. Spear
Inhibition of Hepatocarcinogenesis by the Deletion of the p50 Subunit of NF-{kappa}B in Mice Administered the Peroxisome Proliferator Wy-14,643
Toxicol. Sci., April 1, 2006; 90(2): 331 - 336.
[Abstract] [Full Text] [PDF]


Home page
Toxicol SciHome page
J. M. Shipley, C. H. Hurst, S. S. Tanaka, F. L. DeRoos, J. L. Butenhoff, A. M. Seacat, and D. J. Waxman
trans-Activation of PPAR{alpha} and Induction of PPAR{alpha} Target Genes by Perfluorooctane-Based Chemicals
Toxicol. Sci., July 1, 2004; 80(1): 151 - 160.
[Abstract] [Full Text] [PDF]


Home page
Toxicol SciHome page
J. C. Tharappel, A. Nalca, A. B. Owens, L. Ghabrial, E. C. Konz, H. P. Glauert, and B. T. Spear
Cell Proliferation and Apoptosis Are Altered in Mice Deficient in the NF-{kappa}B p50 Subunit after Treatment with the Peroxisome Proliferator Ciprofibrate
Toxicol. Sci., October 1, 2003; 75(2): 300 - 308.
[Abstract] [Full Text] [PDF]


Home page
Hum Exp ToxicolHome page
V Goll, C Viollon-Abadie, L Nicod, and L Richert
Peroxisome proliferators induce apoptosis and decrease DNA synthesis in hepatoma cell lines
Human and Experimental Toxicology, March 1, 2000; 19(3): 193 - 202.
[Abstract] [PDF]


Home page
J. Lipid Res.Home page
S. Y. Moya-Camarena, J. P. V. Heuvel, S. G. Blanchard, L. A. Leesnitzer, and M. A. Belury
Conjugated linoleic acid is a potent naturally occurring ligand and activator of PPAR{alpha}
J. Lipid Res., August 1, 1999; 40(8): 1426 - 1433.
[Abstract] [Full Text]


Home page
CarcinogenesisHome page
S. Chevalier and R.A. Roberts
G1-arrested FaO cells re-enter the cell cycle upon stimulation with the rodent non-genotoxic hepatocarcinogen nafenopin
Carcinogenesis, July 1, 1999; 20(7): 1209 - 1213.
[Abstract] [Full Text] [PDF]


Home page
EndocrinologyHome page
K.-I. Ohtani, H. Shimizu, N. Sato, and M. Mori
Troglitazone (CS-045) Inhibits {beta}-Cell Proliferation Rate Following Stimulation of Insulin Secretion in HIT-T 15 Cells
Endocrinology, January 1, 1998; 139(1): 172 - 178.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
B. J. Ledwith, C. J. Pauley, L. K. Wagner, C. L. Rokos, D. W. Alberts, and S. Manam
Induction of Cyclooxygenase-2 Expression by Peroxisome Proliferators and Non-tetradecanoylphorbol 12,13-Myristate-type Tumor Promoters in Immortalized Mouse Liver Cells
J. Biol. Chem., February 7, 1997; 272(6): 3707 - 3714.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
S. Pullan, J. Wilson, A. Metcalfe, G. M. Edwards, N. Goberdhan, J. Tilly, J. A. Hickman, C. Dive, and C. H. Streuli
Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium
J. Cell Sci., March 1, 1996; 109(3): 631 - 642.
[Abstract] [PDF]


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bayly, A. C.
Right arrow Articles by Roberts, R. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bayly, A. C.
Right arrow Articles by Roberts, R. A.