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Fig. 5. Recently imported snRNPs are unable to accumulate in speckles. Repeated activation of a region (circled) containing a CB results in rapid accumulation of signal in distant CBs (arrows). No accumulation in speckles can be detected. The left-hand image shows the cell before any laser activation, the central image is immediately after the first activation event and the right-hand image is immediately after the tenth activation event. Bar, 22 µm.