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Figure 6


Fig. 6. In vivo effect of YWK-II antibody on sperm count and apoptotic activity of mouse testis. (A) Adult BALB/c mice were injected with YWK-II antibody (Ab; 40 µg/ml) or control IgG as described in the Materials an Methods and cauda sperm were recovered 48 hours later and sperm count was analyzed by computer-assisted sperm analysis. The data are the mean number of sperm per testis from nine mice (*P<0.05, n=9). (B) In vivo effect of YWK-II antibody on expression level of nuclear p53 and cleaved caspase-3 in mouse testis, demonstrated by western blot analysis.





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