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Figure 3


Fig. 3. Association of Ptc with the Hh complex is independent of Sxl. (A-F) Male salivary gland cells with the SmoD16 deletion allele (and PKAH2). Ci and Ptc colocalize at the plasma membrane and vesicular network (C and F colocalized pixels only). (G) Adult male and female extracts treated with anti-Ci and Cos2 show that Cos2 immunoprecipitates ~16% of the Ptc in males, ~22% in females; Ci immunoprecipitates ~1% of the Ptc in males and ~16% in females.





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