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Fig. 5. Asymmetric cytokinesis. (A,B) Time-lapse images of svkA-knockout cells dividing on a plastic surface. The increasingly asymmetric cleavage furrow inhibits complete separation of the daughter cells (bars, 20 µm). (C) Time-lapse series of projections calculated from stacks of confocal images with GFP-cortexillin I expressed in svkA-knockout cells. The dividing cell shows an asymmetric cleavage furrow and a remaining cytoplasmic bridge that eventually ruptures
8 minutes after the onset of cytokinesis (bar, 5 µm).