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Figure 8


Fig. 8. The ergosterol biosynthetic pathway in budding yeast. Only the ergosterol-specific part of the pathway is shown. Large arrows indicate major regulatory steps. The role of Erg4, Ncp1 and Cbr1, which were isolated in the screen, in the pathway is illustrated. Proteins that depend on Ncp1 and/or Cbr1 are enclosed in a rectangle. Furthermore, it is highlighted whether these reactions depend on Ncp1 and Cbr1 or on Cbr1 alone. The oval denotes Erg4.





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