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Figure 4


Fig. 4. MDCK cells expressing ADAMTS12 fail to form tubular structures in a 3D collagen matrix. Selected clones expressing ADAMTS12, TS12-4 and TS12-22 were grown within a collagen gel for seven days. Morphological changes such as long extensions (arrows) from the cysts are clearly observed in cMDCK and MT1-MDCK clones. Bar, 50 µm.





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