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Figure 3


Fig. 3. Macropinocytosis of catenins in conjunction with E-cadherin. MCF-7 cells were treated with EGF for 10 minutes, fixed and immunolabeled for E-cadherin (green) and nuclei (DAPI; blue), and for either (a) p120ctn (red) or (b) ß-catenin (red). Note localization of a pool of p120ctn and ß-catenin to E-cadherin-positive macropinosomes (arrows). Second, third and fourth panels are magnifications of boxed areas shown in respective first panels. Bars, 20 µm for all first panels; 2 µm for all other panels.





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