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Figure 4


Fig. 4. RNAi-mediated suppression of SNX5 induces fragmentation of the Golgi complex. Suppression of SNX5 alone or SNX5 and SNX6 together leads to morphological changes of the trans-Golgi (stained with TGN46) and the cis-Golgi (stained with GM130), whereas single suppression of SNX1 or SNX6 alone does not appear to have a major effect on TGN organization. Compare also with Fig. 5A for these changes of the TGN morphology. Bars, 20 µm.





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