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Figure 1


Fig. 1. Schematic of ADAM22 variant 1 full length protein and cytoplasmic tail. The cytoplasmic tail has two RSNS 14-3-3 protein consensus binding sites (black boxes in sequence below). Both 14-3-3 binding sites overlie or are adjacent to RXR motifs (underlined in sequence). C-termini are shown of variant 4 (bullet) and variant 1 as well as of the {Delta} C-terminal mutant ({blacktriangleup}).





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