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Fig. 9. Effect of 14,15-EEZE on hypoxia-induced angiogenesis in vivo in the chick chorioallantoic membrane. Methylcellulose discs containing solvent (0.03% DMSO) or 14,15-EEZE (30 µmol/l) were placed on 9-day-old CAMs. After 3 days of incubation under normoxic or hypoxic (14% O2) conditions vessels were stained and photographed and the vessel density calculated. The dashed line on the representative images marks the border of the discs. The bar graph summarizes the results (mean±s.e.m.) obtained from eight eggs per group; **P<0.01 vs the level in solvent-treated eggs (Sol) maintained in hypoxia; *P<0.05 vs the level in solvent-treated eggs maintained in normoxia.





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