Molecular motors implicated in the axonal transport of tau and -synuclein

JCS02558 Supplementary Material

Files in this Data Supplement:

• Movie 1 - Movie 1. Tau-EGFP-containing particles moving within a rat cortical neuron transfected with 0N4R-tau-EGFP. The corresponding stills are shown in Fig. 2A. The movie shows time lapse of 50 images, taken over 75 seconds. The movie displays the images at approximately 33 actual velocity, approximately 1.7 frames/second.

• Movie 2 - Movie 2. Tau-EGFP-containing particles moving within a rat cortical neuron transfected with 0N4R-tau-EGFP. The corresponding stills are shown in Fig. 2B. The movie shows time lapse of 41 images, taken over 100 seconds. The movie displays the images at approximately 33 actual velocity, approximately 1.3 frames/ second.

• Movie 3 - Movie 3. a-Synuclein-EGFP-containing particles moving within a rat cortical neuron transfected with a-synuclein-EGFP. The corresponding stills are shown in Fig. 2C. The movie shows time lapse of 61 images, taken over 153 seconds. The movie displays the images at approximately 33 actual velocity, approximately 1.2 frames/second.

• Movie 4 - Movie 4. a-Synuclein-EGFP-containing particles moving within a rat cortical neuron transfected with a-synuclein-EGFP. The corresponding stills are shown in Fig. 2D. The movie shows time lapse of 61 images, taken over 162 seconds. The movie displays the images at approximately 33 actual velocity, approximately 1.2 frames/second.