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Fig. 2. Western blot analysis of p38 MAPK. (A) Western blot analysis showing that H2O2 increased phosphorylation of p38 MAPK in astrocytes in a dose-dependent manner (P<0.02). (B) SB203580 suppresses H2O2-induced phosphorylation of p38 MAPK (P<0.05). For each sample, the relative intensity of phosphorylated p38 MAPK was normalized to the total p38 MAPK. Values are the mean of three experiments.