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Movie 1
NIH 3T3 cells stably transfected with pcDNA were grown on glass coverslips, serum-starved for 4 days and then stimulated with PDGF. Cells were videotaped from minute 5 to minute 10 after stimulation at 2-second intervals. Motile dorsal ruffles are observed.
Movie 2
NIH 3T3 cells stably transfected with pcDNA-WIP were grown on glass coverslips, serum-starved for 4 days and then stimulated with PDGF. Cells were videotaped from minute 5 to minute 10 after stimulation at 2-second intervals. An increase in number and motility of dorsal ruffles compared to control cells is observed.
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