Fig. 7. NBD-TMA transfer is reduced in aortic endothelium of connexin-deficient mice. The fluorescent tracer NBD-TMA was injected into endothelial cells of wild-type (A), Cx37^–/– (B), Cx40^–/– (C) or Cx37^+/–Cx40^–/– (D) thoracic aorta from 8-12-week-old animals. NBD-TMA transfer was reduced in Cx40^–/– endothelium compared with wild-type, but not in Cx37^–/– endothelium. NBD-TMA transfer was further reduced in Cx37^+/–Cx40^–/– endothelium. Injected cells are marked with an asterisk. Quantification is presented in Table 2. Bar, 50 µm.

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