Fig. 2. Quantification of the number of neurites per cell (A, excluding cells not bearing neurites), the percent of neurite-bearing cells (B), the total neurite length per cell (C) and the number of branch points per neurite (D) from SH-SY5Y cells cultured on endogenous matrix. Wild-type (WT-Rit) and/or constitutively active (CA-Rit) Rit increases neurite initiation (A,B), elongation (C) and branching (D) in comparison with both uninfected cells (Control) and cells infected with adenovirus expressing only green fluorescent protein (GFP). Results are means±s.e.m. across experiments for four separate experiments. Asterisks (*) indicate significant difference compared with Control or GFP only cultures at P<0.05 (ANOVA with Least Significant Difference post hoc test).

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