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Fig. 11. SEM images of cells cultured on patterns with 400 nm pitch. (A) Cell
aligned along nanostructured substrate. (B) Cross-sectional image of cell
patterned substrate. (C) Filopodia extend along the top of ridges and bottom
of grooves. Lamellipodia protrude into the grooves at the cell edge along the
topographic patterns (bottom left) but bridge the grooves at the leading edge
of the cell.
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