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Fig. 6. Demonstration of functional nuclear localization signal within the
N-terminus of p120ctn. Both expression constructs, N1 and N3, localized in the
nucleus (A-D), whereas the C-terminally deleted N1
A (see
Fig. 4) demonstrated diffuse
staining throughout the cell (E,F). Transiently transfected 1205-Lu cells were
detected with MAb M2 (A,C,E) and the nuclei demonstrated with DAPI (B,D,F).
Bar, 50 µm.
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