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Fig. 2. A model of asymmetric cell division based upon ttk69 translational regulation. (A) In the IIb precursor, MSI (red) prevents ttk69 mRNA (purple) from being translated into protein, whereas in the IIa precursor (non-neuronal cell; pink) TTK69 protein is translated. Why MSI does not function in the IIa precursor remains to be elucidated.

(B) In the absence of MSI protein in the msi1 mutant, the IIb precursor is transformed into a IIa precursor, thus causing the `double bristle' phenotype.





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