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Fig. 4. Association frequencies of the centromere-near with the telomere-near
region in haploid strains (see Fig.
1B), monitored by adjacent FISH probes (probes 1 and 2, see
Fig. 1C). Only in the presence
of both the non-allelic tetO repeats and the TetR protein is the
association high. With tetO only, or after inhibition of TetR binding
to tetO by addition of tetracycline, association is as low as in the
wildtype. The experiments were repeated five times and 50 nuclei were
evaluated in each.
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