spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 4. Model of Munc13-1 activation by DAG. See text for details. Note that only one mechanism of DAG synthesis (i.e. PI-PLCß) is depicted here. Other PI-PLC activities are likely to also activate Munc13s. Indeed, PI-PLC{delta} may be responsible for activation of Munc13-1 during high-frequency stimulation and intrasynaptic accumulation of Ca2+.





Right arrow Return to article