Fig. 4. Effect of RGD peptides on TSP-1-induced cellular signals. (A) Histograms show the effect of RGD peptide (0.1 mM) on the TSP-1-induced tyrosine phosphorylation of signalling molecules as determined by densitometric analysis of western blots. Each bar represents the mean±s.e.m. of four separate cell strains. Data are expressed as a percentage of the TSP-1-stimulated response, which was taken to be 100% Representative western blots depicting tyrosine phosphorylation of FAK, p85PI3K and Erk2 are shown above the relevant bar on the histogram.

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