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Fig. 1. Effect of RGD peptide on cellular responses. (A) Histogram shows the effect of the RGD and ESP peptides (0.1 mM) on TSP-induced chemotaxis of quiescent (serum-deprived) cells. Each bar represents the mean±s.e.m. of three separate cell strains. Data are expressed as a percentage of the stimulated response (449±112 cells), which was taken to be 100%. (B) Histogram shows the effect of the RGD peptide (0.1 mM) on TSP-1 and PDGF-induced chemotaxis of cells through collagen-coated filters. Each bar represents the mean±s.e.m. of 3-5 separate cell strains. Data are expressed as a percentage of the stimulated response (TSP-1, 343±123 cells; PDGF-BB, 767±98 cells n=3), which was taken to be 100%.





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