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Fig. 3. Frames from the simulation movie showing the progression of the MSP cytoskeleton as the cell moves forward. The same time interval elapses between successive shaded cell ‘shadows’. Bottom, simulation of translocation with ‘normal’ substrate friction. Top, simulation with the cell body friction increased four-fold over the normal run. Note that the cell body moves much more slowly, but the lamellipod shape changes very little.





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