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Fig. 6. PEDF triggered differentiation in neuroblastoma tumors in vivo. A total of 2 ug PEDF/day for 4 days were injected into subcutaneous SK-N-BE(2) tumors raised in nude mice. Tumors were excised, fixed and stained for neurofilament protein. Vehicle treated tumors (A,B) and rPEDF treated tumors (C,D) are shown at low power (A,C) and high power (B,D). The asterisk indicates an injection site.





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