
Fig. 8. Binding of Fn and 42 kDa Fn fragment to the surfaces of WI-38 fibroblasts
is stimulated by TGFß. (A) Binding of [125I]42 kDa fragment to
untreated or TGFß-treated cells in suspension. (B) Binding of
[125I]Fn to untreated or TGFß-treated cells in suspension.
Nonspecific binding in the presence of excess unlabeled 42 kDa fragment or Fn
was subtracted. Where indicated, cells were incubated with 20 µg/ml
anti-tTG antibody. The results are representative of three independent
experiments (mean±s.e.m.).